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    LCN2 lipocalin 2 [ Homo sapiens (human) ]

    Gene ID: 3934, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Lipocalin-2-mediated intestinal epithelial cells pyroptosis via NF-kappaB/NLRP3/GSDMD signaling axis adversely affects inflammation in colitis.

    Lipocalin-2-mediated intestinal epithelial cells pyroptosis via NF-κB/NLRP3/GSDMD signaling axis adversely affects inflammation in colitis.
    Yang Y, Li S, Liu K, Zhang Y, Zhu F, Ben T, Chen Z, Zhi F.

    08/22/2024
    Emerging insights into Lipocalin-2: Unraveling its role in Parkinson's Disease.

    Emerging insights into Lipocalin-2: Unraveling its role in Parkinson's Disease.
    Qiu R, Cai Y, Su Y, Fan K, Sun Z, Zhang Y.

    08/13/2024
    Neutrophil Gelatinase-Associated Lipocalin for the Differentiation of Mucinous Pancreatic Cystic Lesions.

    Neutrophil Gelatinase-Associated Lipocalin for the Differentiation of Mucinous Pancreatic Cystic Lesions.
    Olar MP, Iacobescu M, Bolboacă SD, Pojoga C, Moșteanu O, Seicean R, Rusu I, Banc O, Iuga CA, Seicean A., Free PMC Article

    04/2/2024
    Serum Lipocalin-2 Levels as a Biomarker in Pre- and Post-Pubertal Klinefelter Syndrome Patients: A Pilot Study.

    Serum Lipocalin-2 Levels as a Biomarker in Pre- and Post-Pubertal Klinefelter Syndrome Patients: A Pilot Study.
    Paparella R, Ferraguti G, Fiore M, Menghi M, Micangeli G, Tarani F, Ligotino A, Messina MP, Ceccanti M, Minni A, Barbato C, Lucarelli M, Tarani L, Petrella C., Free PMC Article

    03/13/2024
    Lipocalin 2 (LCN2) confers acquired resistance to almonertinib in NSCLC through LCN2-MMP-9 signaling pathway.

    Lipocalin 2 (LCN2) confers acquired resistance to almonertinib in NSCLC through LCN2-MMP-9 signaling pathway.
    Shi C, Wang C, Fu Z, Liu J, Zhou Y, Cheng B, Zhang C, Li S, Zhang Y.

    03/5/2024
    LCN2 Promotes Proliferation and Glycolysis by Activating the JAK2/STAT3 Signaling Pathway in Hepatocellular Carcinoma.

    LCN2 Promotes Proliferation and Glycolysis by Activating the JAK2/STAT3 Signaling Pathway in Hepatocellular Carcinoma.
    Han B, An Z, Gong T, Pu Y, Liu K.

    02/21/2024
    LCN2: Versatile players in breast cancer.

    LCN2: Versatile players in breast cancer.
    Bao Y, Yan Z, Shi N, Tian X, Li J, Li T, Cheng X, Lv J.

    02/9/2024
    Quantitative Proteomics of Tissue-Infiltrating T Cells From CRC Patients Identified Lipocalin-2 Induces T-Cell Apoptosis and Promotes Tumor Cell Proliferation by Iron Efflux.

    Quantitative Proteomics of Tissue-Infiltrating T Cells From CRC Patients Identified Lipocalin-2 Induces T-Cell Apoptosis and Promotes Tumor Cell Proliferation by Iron Efflux.
    Che R, Wang Q, Li M, Shen J, Ji J., Free PMC Article

    02/1/2024
    Relationship between methylenetetrahydrofolate reductase C677T gene polymorphism and neutrophil gelatinase-associated lipocalin in early renal injury in H-type hypertension.

    Relationship between methylenetetrahydrofolate reductase C677T gene polymorphism and neutrophil gelatinase-associated lipocalin in early renal injury in H-type hypertension.
    Zhang C, Xin QP, Xie YB, Guo XY, Xing EH, Dou ZJ, Zhao C., Free PMC Article

    01/31/2024
    Neutrophil gelatinase-associated lipocalin (NGAL) and inflammatory markers in schizophrenia: A comparative analysis of drug-naive schizophrenia patients, remitted patients, and healthy controls.

    Neutrophil gelatinase-associated lipocalin (NGAL) and inflammatory markers in schizophrenia: A comparative analysis of drug-naive schizophrenia patients, remitted patients, and healthy controls.
    Çiftci H, Aşut G, Kaya H, Çakmak IB, Aydıner Yılmaz M, Çöpür A, Çalcı E, Fırat Oğuz E, Turhan T, Göka E.

    01/27/2024
    Serum lipocalin-2 levels are decreased in patients with leprosy.

    Serum lipocalin-2 levels are decreased in patients with leprosy.
    Bazid HAS, Shoeib MA, Shoeib MM, Sharaf REA, Mosatafa MI, Abd El Gayed EM.

    01/27/2024
    Urinary neutrophil gelatinase-associated lipocalin (uNGAL) and kidney injury molecule-1 (uKIM-1) as markers of active lupus nephritis.

    Urinary neutrophil gelatinase-associated lipocalin (uNGAL) and kidney injury molecule-1 (uKIM-1) as markers of active lupus nephritis.
    Ibrahim WHM, Sabry AA, Abdelmoneim AR, Marzouk HFA, AbdelFattah RM., Free PMC Article

    01/15/2024
    Lipocalin-2 promotes neutrophilic inflammation in nasal polyps and its value as biomarker.

    Lipocalin-2 promotes neutrophilic inflammation in nasal polyps and its value as biomarker.
    Zhang C, Wang H, Hu L, Zhang Q, Chen J, Shi L, Song X, Liu J, Xue K, Wang J, Wang D, Sun X.

    01/9/2024
    Measurement of Neutrophil Gelatinase-Associated Lipocalin (Ngal) Following Neuroradiological Procedure/s in Patients with Aneurysmal Subarachnoid Hemorrhage: A Preliminary Study.

    Measurement of Neutrophil Gelatinase-Associated Lipocalin (Ngal) Following Neuroradiological Procedure/s in Patients with Aneurysmal Subarachnoid Hemorrhage: A Preliminary Study.
    Kaushal A, Chouhan RS, Bindra A, Gaikwad S, Subbiah V.

    01/8/2024
    Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.

    Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
    Pan Z, Li B, Lu P, Rong G, Wang X.

    01/5/2024
    SARS-CoV-2 infection induces expression and secretion of lipocalin-2 and regulates iron in a human lung cancer xenograft model.

    SARS-CoV-2 infection induces expression and secretion of lipocalin-2 and regulates iron in a human lung cancer xenograft model.
    Park S, Kim D, Kim J, Kwon HJ, Lee Y., Free PMC Article

    01/4/2024
    Tumor-associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin-2.

    Tumor-associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin-2.
    Li H, Liu Y, Liu Y, Xu L, Sun Z, Zheng D, Liu X, Song C, Zhang Y, Liang H, Yang B, Tian X, Luo J, Chang Q., Free PMC Article

    01/3/2024
    Plasma neutrophil gelatinase-associated lipocalin predicts renal tubulointerstitial injury in patients with IgA nephropathy.

    Plasma neutrophil gelatinase-associated lipocalin predicts renal tubulointerstitial injury in patients with IgA nephropathy.
    Zhao W, Jiang J, Chen W.

    12/27/2023
    Increasing expression of STING by ERalpha antagonizes LCN2 downregulation during chronic endometritis.

    Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis.
    Chu M, He S, Zhao H, Yin S, Liu Z, Zhang W, Liu X, Bao H.

    12/6/2023
    Role of LCN2 in a murine model of hindlimb ischemia and in peripheral artery disease patients, and its potential regulation by miR-138-5P.

    Role of LCN2 in a murine model of hindlimb ischemia and in peripheral artery disease patients, and its potential regulation by miR-138-5P.
    Saenz-Pipaon G, Jover E, van der Bent ML, Orbe J, Rodriguez JA, Fernández-Celis A, Quax PHA, Paramo JA, López-Andrés N, Martín-Ventura JL, Nossent AY, Roncal C.

    11/29/2023
    KIM-1, IL-18, and NGAL, in the Machine Learning Prediction of Kidney Injury among Children Undergoing Hematopoietic Stem Cell Transplantation-A Pilot Study.

    KIM-1, IL-18, and NGAL, in the Machine Learning Prediction of Kidney Injury among Children Undergoing Hematopoietic Stem Cell Transplantation-A Pilot Study.
    Musiał K, Stojanowski J, Miśkiewicz-Bujna J, Kałwak K, Ussowicz M., Free PMC Article

    11/16/2023
    Neutrophil gelatinase-associated lipocalin serum level: A potential noninvasive biomarker of endometriosis?

    Neutrophil gelatinase-associated lipocalin serum level: A potential noninvasive biomarker of endometriosis?
    Guney G, Taskin MI, Laganà AS, Tolu E, Aslan F, Hismiogullari AA, Kaya C., Free PMC Article

    11/7/2023
    The contribution of IL-17A-dependent low LCN2 levels to Helicobacter pylori infection: Insights from clinical and experimental studies.

    The contribution of IL-17A-dependent low LCN2 levels to Helicobacter pylori infection: Insights from clinical and experimental studies.
    Cheng M, Zheng Y, Fan Y, Yan P, Zhao W.

    11/6/2023
    Circulating lipocalin-2 and features of metabolic syndrome in community-dwelling older women: A cross-sectional study.

    Circulating lipocalin-2 and features of metabolic syndrome in community-dwelling older women: A cross-sectional study.
    Bauer C, Sim M, Prince RL, Zhu K, Lim EM, Byrnes E, Pavlos N, Lim WH, Wong G, Lewis JR, Levinger I.

    09/21/2023
    Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study.

    Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study.
    Wang Q, Lin Q, Wang H, Tang M, Fan K, Zhang Z, Huang E, Zhang W, Wang F, Ou Q, Liu X., Free PMC Article

    09/13/2023
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