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    LAMC2 laminin subunit gamma 2 [ Homo sapiens (human) ]

    Gene ID: 3918, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Oncogenic Roles of Laminin Subunit Gamma-2 in Intrahepatic Cholangiocarcinoma via Promoting EGFR Translation.

    Oncogenic Roles of Laminin Subunit Gamma-2 in Intrahepatic Cholangiocarcinoma via Promoting EGFR Translation.
    Zhang J, Ji F, Tan Y, Zhao L, Zhao Y, Liu J, Shao L, Shi J, Ye M, He X, Jin J, Zhao B, Huang J, Roessler S, Zheng X, Ji J., Free PMC Article

    10/22/2024
    Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway.

    Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway.
    Wang D, Keyoumu K, Yu R, Wen D, Jiang H, Liu X, Di X, Zhang S., Free PMC Article

    05/21/2024
    LAMC2 regulates the proliferation, invasion, and metastasis of gastric cancer via PI3K/Akt signaling pathway.

    LAMC2 regulates the proliferation, invasion, and metastasis of gastric cancer via PI3K/Akt signaling pathway.
    Cheng L, Li X, Dong W, Yang J, Li P, Qiang X, Yin J, Guo L., Free PMC Article

    05/9/2024
    LncRNAs-Regulated High Expression of LAMC2 Reveals a Prognostic and Immunological Value in Pancreatic Adenocarcinoma.

    LncRNAs-Regulated High Expression of LAMC2 Reveals a Prognostic and Immunological Value in Pancreatic Adenocarcinoma.
    Liu J, Wang M, Wang M, Wang F, Zhang B.

    03/4/2024
    LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer.

    LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer.
    Tong D, Wang X, Liu L, Wen T, Chen Q, Huang C., Free PMC Article

    02/16/2024
    LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.

    LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.
    Erice O, Narayanan S, Feliu I, Entrialgo-Cadierno R, Malinova A, Vicentini C, Guruceaga E, Delfino P, Trajkovic-Arsic M, Moreno H, Valencia K, Blanco E, Macaya I, Öhlund D, Khatri P, Lecanda F, Scarpa A, Siveke JT, Corbo V, Ponz-Sarvise M, Vicent S.

    03/16/2023
    LncRNA T376626 is a promising serum biomarker and promotes proliferation, migration, and invasion via binding to LAMC2 in triple-negative breast cancer.

    LncRNA T376626 is a promising serum biomarker and promotes proliferation, migration, and invasion via binding to LAMC2 in triple-negative breast cancer.
    He Y, Xiao B, Lei T, Xuan J, Zhu Y, Kuang Z, Liu J, He J, Li L, Sun Z.

    02/27/2023
    LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis.

    LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis.
    Fu T, Liu JX, Xie J, Gao Z, Yang Z., Free PMC Article

    11/26/2022
    LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer.

    LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer.
    Cave DD, Buonaiuto S, Sainz B Jr, Fantuz M, Mangini M, Carrer A, Di Domenico A, Iavazzo TT, Andolfi G, Cortina C, Sevillano M, Heeschen C, Colonna V, Corona M, Cucciardi A, Di Guida M, Batlle E, De Luca A, Lonardo E., Free PMC Article

    11/5/2022
    Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade.

    Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade.
    Kirtonia A, Pandey AK, Ramachandran B, Mishra DP, Dawson DW, Sethi G, Ganesan TS, Koeffler HP, Garg M., Free PMC Article

    07/2/2022
    [Correlation between Serum G-CSF Level and Immune Function in Children with Aplastic Anemia].

    [Correlation between Serum G-CSF Level and Immune Function in Children with Aplastic Anemia].
    Ren R, Han J.

    06/18/2022
    Long non-coding RNA BBOX1-antisense RNA 1 enhances cell proliferation and migration and suppresses apoptosis in oral squamous cell carcinoma via the miR-3940-3p/laminin subunit gamma 2 axis.

    Long non-coding RNA BBOX1-antisense RNA 1 enhances cell proliferation and migration and suppresses apoptosis in oral squamous cell carcinoma via the miR-3940-3p/laminin subunit gamma 2 axis.
    Zhao C, Shi W, Chen M., Free PMC Article

    05/21/2022
    Orchestrated expression of vasculogenic mimicry and laminin-5gamma2 is an independent prognostic marker in oral squamous cell carcinoma.

    Orchestrated expression of vasculogenic mimicry and laminin-5γ2 is an independent prognostic marker in oral squamous cell carcinoma.
    Saha D, Mitra D, Alam N, Sen S, Mitra Mustafi S, Mandal S, Majumder B, Murmu N., Free PMC Article

    04/16/2022
    Long non-coding RNA CASC9 promotes tumor progression in oral squamous cell carcinoma by regulating microRNA-545-3p/laminin subunit gamma 2.

    Long non-coding RNA CASC9 promotes tumor progression in oral squamous cell carcinoma by regulating microRNA-545-3p/laminin subunit gamma 2.
    Ning B, Guo S, Mei Y., Free PMC Article

    02/26/2022
    Serum Laminin gamma2 Monomer as a Diagnostic and Predictive Biomarker for Hepatocellular Carcinoma.

    Serum Laminin γ2 Monomer as a Diagnostic and Predictive Biomarker for Hepatocellular Carcinoma.
    Yamashita T, Koshikawa N, Shimakami T, Terashima T, Nakagawa M, Nio K, Horii R, Iida N, Kawaguchi K, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kitao A, Kobayashi S, Takahara S, Imai Y, Yoshimura K, Murayama T, Nakamoto Y, Yoshida E, Yoshimura T, Seiki M, Kaneko S.

    01/8/2022
    Novel LAMC2 fusion protein has tumor-promoting properties in ovarian carcinoma.

    Novel LAMC2 fusion protein has tumor-promoting properties in ovarian carcinoma.
    Daisuke H, Kato H, Fukumura K, Mayeda A, Miyagi Y, Seiki M, Koshikawa N., Free PMC Article

    12/25/2021
    LAMC2 acts as a novel therapeutic target of cetuximab in laryngeal cancer.

    LAMC2 acts as a novel therapeutic target of cetuximab in laryngeal cancer.
    Wang QY, Liu YC, Zhou SH, Chen HH.

    12/18/2021
    ITGA2, LAMB3, and LAMC2 may be the potential therapeutic targets in pancreatic ductal adenocarcinoma: an integrated bioinformatics analysis.

    ITGA2, LAMB3, and LAMC2 may be the potential therapeutic targets in pancreatic ductal adenocarcinoma: an integrated bioinformatics analysis.
    Islam S, Kitagawa T, Baron B, Abiko Y, Chiba I, Kuramitsu Y., Free PMC Article

    11/13/2021
    hsamiR55803p inhibits oral cancer cell viability, proliferation and migration by suppressing LAMC2.

    hsa‑miR‑5580‑3p inhibits oral cancer cell viability, proliferation and migration by suppressing LAMC2.
    Fang R, Lu Q, Xu B., Free PMC Article

    10/23/2021
    Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing.

    Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing.
    Zheng R, Du M, Ge Y, Gao F, Xin J, Lv Q, Qin C, Zhu Y, Gu C, Wang M, Zhu Q, Guo Z, Ben S, Chu H, Ye D, Zhang Z, Wang M., Free PMC Article

    10/23/2021
    LAMC2 promotes cancer progression and gemcitabine resistance through modulation of EMT and ATP-binding cassette transporters in pancreatic ductal adenocarcinoma.

    LAMC2 promotes cancer progression and gemcitabine resistance through modulation of EMT and ATP-binding cassette transporters in pancreatic ductal adenocarcinoma.
    Okada Y, Takahashi N, Takayama T, Goel A., Free PMC Article

    10/2/2021
    Identification of laminin gamma2 as a prognostic and predictive biomarker for determining response to gemcitabine-based therapy in pancreatic ductal adenocarcinoma.

    Identification of laminin γ2 as a prognostic and predictive biomarker for determining response to gemcitabine-based therapy in pancreatic ductal adenocarcinoma.
    Okada Y, Nishiwada S, Yamamura K, Sho M, Baba H, Takayama T, Goel A., Free PMC Article

    10/2/2021
    A single-nucleotide polymorphism in lnc-LAMC2-1:1 interferes with its interaction with miR-128 to alter the expression of deleted in colorectal cancer and its effect on the survival rate of subjects with ovarian cancer.

    A single-nucleotide polymorphism in lnc-LAMC2-1:1 interferes with its interaction with miR-128 to alter the expression of deleted in colorectal cancer and its effect on the survival rate of subjects with ovarian cancer.
    Wang Q, Li XP, Zhou X, Yang CF, Zhu Z.

    07/17/2021
    MicroRNA-134 inhibits tumor stem cell migration and invasion in oral squamous cell carcinomas via downregulation of PI3K-Akt signaling pathway by inhibiting LAMC2 expression.

    MicroRNA-134 inhibits tumor stem cell migration and invasion in oral squamous cell carcinomas via downregulation of PI3K-Akt signaling pathway by inhibiting LAMC2 expression.
    Zhou YM, Yao YL, Liu W, Shen XM, Shi LJ, Wu L.

    06/12/2021
    Laminin332 mediates proliferation, apoptosis, invasion, migration and epithelialtomesenchymal transition in pancreatic ductal adenocarcinoma.

    Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.
    Huang C, Chen J., Free PMC Article

    05/1/2021
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