| HIF-1alpha-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experiments. | HIF-1α-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experiments.
Bai J, Zhao Y, Shi K, Fan Y, Ha Y, Chen Y, Luo B, Lu Y, Jie W, Shen Z., Free PMC Article | 05/8/2024 |
| Circ_0124208 Promotes the Progression of Hepatocellular Carcinoma by Regulating the miR-338-3p/LAMC1 Axis. | Circ_0124208 Promotes the Progression of Hepatocellular Carcinoma by Regulating the miR-338-3p/LAMC1 Axis.
Chen J, Liu Z, Zhong Y, Chen H, Xie L. | 09/27/2023 |
| NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1. | NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1.
Jonnakuti VS, Ji P, Gao Y, Lin A, Chu Y, Elrod N, Huang KL, Li W, Yalamanchili HK, Wagner EJ. | 08/4/2023 |
| Hsa_circ_0005085 may suppress cutaneous squamous cell carcinoma growth and metastasis through targeting the miR-186-5p/LAMC1 axis. | Hsa_circ_0005085 may suppress cutaneous squamous cell carcinoma growth and metastasis through targeting the miR-186-5p/LAMC1 axis.
Wang L, Liu Y, Gao Q, Hu R., Free PMC Article | 06/29/2023 |
| Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral reflux. | Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral reflux.
Bartik ZI, Sillén U, Djos A, Lindholm A, Fransson S., Free PMC Article | 12/3/2022 |
| Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity. | Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity.
Gholami M, Zoughi M, Behboo R, Taslimi R, Kazemeini A, Bastami M, Hasani-Ranjbar S, Larijani B, Amoli MM., Free PMC Article | 11/12/2022 |
| A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn's Disease and DSS Colitis. | A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn's Disease and DSS Colitis.
Lindholm M, Di Sabatino A, Manon-Jensen T, Mazza G, Madsen GI, Giuffrida P, Pinzani M, Krag A, Karsdal MA, Kjeldsen J, Mortensen JH. | 07/23/2022 |
| LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis. | LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
Fang Y, Dou R, Huang S, Han L, Fu H, Yang C, Song J, Zheng J, Zhang X, Liu K, Xiang Z, Zhang X, Wang S, Xiong B., Free PMC Article | 05/14/2022 |
| LAMC1 upregulation via TGFbeta induces inflammatory cancer-associated fibroblasts in esophageal squamous cell carcinoma via NF-kappaB-CXCL1-STAT3. | LAMC1 upregulation via TGFβ induces inflammatory cancer-associated fibroblasts in esophageal squamous cell carcinoma via NF-κB-CXCL1-STAT3.
Fang L, Che Y, Zhang C, Huang J, Lei Y, Lu Z, Sun N, He J., Free PMC Article | 04/16/2022 |
| Fuchs Endothelial Corneal Dystrophy associated risk variant, rs3768617 in LAMC1 shows allele specific binding of GFI1B. | Fuchs Endothelial Corneal Dystrophy associated risk variant, rs3768617 in LAMC1 shows allele specific binding of GFI1B.
Chakraborty M, Das RK, Samal S, Das S, Alone DP. | 02/26/2022 |
| A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study. | A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study.
Yu Y, Mao L, Cheng Z, Zhu X, Cui J, Fu X, Cheng J, Zhou Y, Qiu A, Dong Y, Zhuang X, Lu Y, Lian Y, Tian T, Wu S, Chu M. | 02/12/2022 |
| Integrin subunit beta1 and laminin gamma1 chain expression: a potential prognostic biomarker in cervical cancer. | Integrin subunit β1 and laminin γ1 chain expression: a potential prognostic biomarker in cervical cancer.
Zacapala-Gómez AE, C Alarcón-Romero LD, Mendoza-Catalán MA, Salmerón-Bárcenas EG, I Zubillaga-Guerrero M, Torres-Rojas FI, Illades-Aguiar B. | 10/23/2021 |
| LAMC1 is related to the poor prognosis of patients with gastric cancer and facilitates cancer cell malignancies. | LAMC1 is related to the poor prognosis of patients with gastric cancer and facilitates cancer cell malignancies.
Han ZR, Jiang XL, Fan WC. | 08/14/2021 |
| Common variants in LAMC1 confer risk for pelvic organ prolapse in Chinese population. | Common variants in LAMC1 confer risk for pelvic organ prolapse in Chinese population.
Chen J, Li L, Lang J, Zhu L., Free PMC Article | 06/5/2021 |
| LAMC1 is a prognostic factor and a potential therapeutic target in endometrial cancer. | LAMC1 is a prognostic factor and a potential therapeutic target in endometrial cancer.
Kunitomi H, Kobayashi Y, Wu RC, Takeda T, Tominaga E, Banno K, Aoki D., Free PMC Article | 04/24/2021 |
| Abnormal Endothelial Gene Expression Associated With Early Coronary Atherosclerosis. | Abnormal Endothelial Gene Expression Associated With Early Coronary Atherosclerosis.
Hebbel RP, Wei P, Milbauer L, Corban MT, Solovey A, Kiley J, Pattee J, Lerman LO, Pan W, Lerman A., Free PMC Article | 03/13/2021 |
| The present study provides first quantitative evidence that corneal edema (as measured by CPTR3.5) may specifically correlate with increased corneal endothelial expression of ECM components FN1 , LAMC1 and COL4A1. | Correlation of extracellular matrix-related gene expression with objective Fuchs endothelial corneal dystrophy severity.
Matthaei M, Leitl C, Cursiefen C, Heindl LM. | 08/1/2020 |
| High expression of LAMC1 and PKM2 was detected in tumors of hepatocellular carcinoma (HCC) patients. In HCC cells, LAMC1 down-regulation inhibited cell proliferation, reduced glucose consumption and lactate production, while LAMC1 up-regulation had the opposite effect. Authors speculated that LAMC1 was implicated in the progression of HCC probably by regulating PKM2 expression through PTEN/AKT pathway. | Lamc1 promotes the Warburg effect in hepatocellular carcinoma cells by regulating PKM2 expression through AKT pathway.
Ye G, Qin Y, Wang S, Pan D, Xu S, Wu C, Wang X, Wang J, Ye H, Shen H., Free PMC Article | 07/11/2020 |
| Polymorphism in the ERalpha gene is associated with an increased risk for advanced Pelvic Organ Prolapse. However, polymorphism in the LAMC1 gene does not seem to be associated with such risk. | Estrogen receptor and laminin genetic polymorphism among women with pelvic organ prolapse.
Nakad B, Fares F, Azzam N, Feiner B, Zilberlicht A, Abramov Y. | 08/4/2018 |
| We conclude that LAMC1 mRNA acts as a trans regulator to stimulate CD151 expression by competing for miR-124 binding in hepatocellular carcinoma cells. | LAMC1 mRNA promotes malignancy of hepatocellular carcinoma cells by competing for MicroRNA-124 binding with CD151.
Yang ZP, Ma HS, Wang SS, Wang L, Liu T. | 04/14/2018 |
| Further gene expression analyses demonstrated significantly higher expression of LAMC1 gene in colorectal cancer (CRC) tumor tissues than that in adjacent non-cancerous tissues (P = 0.0004). These findings strongly suggest that the functional SNP located at TFBSs, rs6695837 might contribute to CRC susceptibility, and the exact biological mechanism awaits further research. | A functional polymorphism located at transcription factor binding sites, rs6695837 near LAMC1 gene, confers risk of colorectal cancer in Chinese populations.
Lou J, Gong J, Ke J, Tian J, Zhang Y, Li J, Yang Y, Zhu Y, Gong Y, Li L, Chang J, Zhong R, Miao X. | 09/2/2017 |
| The rs780094 [1.34 (1.21-1.49); p = 8.57 x 10(-8) ] on chr 2 at the glucokinase regulatory protein (GCKR) locus was similarly significantly associated, while the rs10911205 [1.29 (1.16-1.44); p = 3.52 x 10(-6) ] on chr1 at the laminin subunit gamma-1 (LAMC1) locus showed suggestive association with disease. | A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.
Ram R, Wakil SM, Muiya NP, Andres E, Mazhar N, Hagos S, Alshahid M, Meyer BF, Morahan G, Dzimiri N. | 07/1/2017 |
| Our results show that miR-181a is down-regulated in glioblastoma multiforme (GBM) patients. The three target genes, ANGPT2, ARHGAP18 and LAMC1, are negatively correlated with the expression of miR-181a. Moreover, high expression of ANGPT2 or LAMC1 together with large size of GBM is correlated with a shorter median overall survival | The correlation of microRNA-181a and target genes with poor prognosis of glioblastoma patients.
Huang SX, Zhao ZY, Weng GH, He XY, Wu CJ, Fu CY, Sui ZY, Zhong XM, Liu T. | 04/1/2017 |
| miR-506 acts as a tumor suppressor and inhibits malignancy of colorectal cancer cells through directly targeting LAMC1. | MicroRNA-506 Inhibits Malignancy of Colorectal Carcinoma Cells by Targeting LAMC1.
Zu C, Liu T, Zhang G. | 01/14/2017 |
| Case Report: Anti-laminin-gamma 1 pemphigoid in patient with generalized pustular psoriasis and psoriasis vulgaris. | Anti-laminin-gamma 1 Pemphigoid with Generalized Pustular Psoriasis and Psoriasis Vulgaris.
Fujimura Y, Natsuga K, Hamade Y, Nomura Y, Kaku Y, Muramatsu R, Shimizu H. | 10/22/2016 |