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    KRT81 keratin 81 [ Homo sapiens (human) ]

    Gene ID: 3887, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity.

    Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity.
    Kang DS, Moriarty A, Wang YJ, Thomas A, Hao J, Unger BA, Klotz R, Ahmmed S, Amzaleg Y, Martin S, Vanapalli S, Xu K, Smith A, Shen K, Yu M., Free PMC Article

    02/7/2024
    KRT81 Knockdown Inhibits Malignant Progression of Melanoma Through Regulating Interleukin-8.

    KRT81 Knockdown Inhibits Malignant Progression of Melanoma Through Regulating Interleukin-8.
    Zhang K, Liang Y, Zhang W, Zeng N, Tang S, Tian R.

    10/23/2021
    A Polymorphism at the microRNA Binding Site in the 3' Untranslated Region of KRT81 Is Associated with Breast Cancer.

    A Polymorphism at the microRNA Binding Site in the 3' Untranslated Region of KRT81 Is Associated with Breast Cancer.
    Sha Z, Lai R, Zhang X, Zhao Y, Wu J, Geng C, Guo Z.

    10/24/2020
    analysis of KRT81 and HNF1A expression by IHC is a reliable way to identify biologically relevant subtypes of PDAC that could easily be integrated into common pathologic practice.

    Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response.
    Muckenhuber A, Berger AK, Schlitter AM, Steiger K, Konukiewitz B, Trumpp A, Eils R, Werner J, Friess H, Esposito I, Klöppel G, Ceyhan GO, Jesinghaus M, Denkert C, Bahra M, Stenzinger A, Sprick MR, Jäger D, Springfeld C, Weichert W.

    07/27/2019
    Results show that full size KRT81 is expressed in normal breast epithelial cells and breast cancer cells, and indicate that KRT81 contributes to the migration and invasion of breast cancer cells.

    Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.
    Nanashima N, Horie K, Yamada T, Shimizu T, Tsuchida S.

    05/13/2017
    The analysis of the KRT81rs3660G>C polymorphism may be useful to identify non-small cell lung cancer patients at high risk of a poor disease outcome.

    A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.
    Lee SY, Choi JE, Jeon HS, Hong MJ, Choi YY, Kang HG, Yoo SS, Lee EB, Jeong JY, Lee WK, Lee J, Cha SI, Kim CH, Kim YT, Jheon S, Son JW, Park JY.

    05/14/2016
    Novel mutations causing monilethrix are reported in KRT81, KRT83, and KRT86.

    Novel KRT83 and KRT86 mutations associated with monilethrix.
    van Steensel M, Vreeburg M, Urbina MT, López P, Morice-Picard F, van Geel M.

    12/5/2015
    MiRNA-related single nucleotide polymorphism sites of KRT81 is associated with non-Hodgkin's lymphoma.

    A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.
    Xie Y, Diao L, Zhang L, Liu C, Xu Z, Liu S.

    05/10/2014
    Overall survival was significantly longer in multiple myeloma patients with KRT81 rs3660 C/C variant

    Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation.
    de Larrea CF, Navarro A, Tejero R, Tovar N, Díaz T, Cibeira MT, Rosiñol L, Ferrer G, Rovira M, Rozman M, Monzó M, Bladé J.

    10/27/2012
    KRT81 has emerged as a promising immunohistochemical marker for the identification of squamous cell lung carcinoma

    A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma.
    Campayo M, Navarro A, Viñolas N, Tejero R, Muñoz C, Diaz T, Marrades R, Cabanas ML, Gimferrer JM, Gascon P, Ramirez J, Monzo M., Free PMC Article

    12/10/2011
    Transfected p65 induces transcriptional activation of Hb1.

    Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA.
    Gilon M, Sher N, Cohen S, Gat U.

    01/21/2010
    EBV-dependent upregulation of hHb1-DeltaN in gastric carcinoma cell lines

    Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).
    Nishikawa J, Kiss C, Imai S, Takada K, Okita K, Klein G, Szekely L.

    01/21/2010
    The KRTHB1 expression uniformly occurred in the midcortex region.

    Keratins of the human hair follicle.
    Langbein L, Schweizer J.

    01/21/2010
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