| Toxoplasma gondii infection regulates apoptosis of host cells via miR-185/ARAF axis. | Toxoplasma gondii infection regulates apoptosis of host cells via miR-185/ARAF axis.
Su D, Zhu S, Hou Z, Hao F, Xu K, Xu F, Zhu Y, Liu D, Xu J, Tao J., Free PMC Article | 11/1/2023 |
| MiR-185-5p regulates the development of myocardial fibrosis. | MiR-185-5p regulates the development of myocardial fibrosis.
Lin R, Rahtu-Korpela L, Szabo Z, Kemppi A, Skarp S, Kiviniemi AM, Lepojärvi ES, Halmetoja E, Kilpiö T, Porvari K, Pakanen L, Tolva J, Paakkanen R, Segersvärd H, Tikkanen I, Laine M, Sinisalo J, Lakkisto P, Huikuri H, Magga J, Junttila J, Kerkelä R. | 05/14/2022 |
| MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1. | MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1.
Zhang J, Wang X, Jiang H, Yang F, Du Y, Wang L, Hong B. | 05/14/2022 |
| Study on the Effect and Mechanism of miR-185 on Lower Extremity Deep Venous Thrombosis. | Study on the Effect and Mechanism of miR-185 on Lower Extremity Deep Venous Thrombosis.
Lu R, Zhu W, Sun H, Zhang L, Yu Z, Nie Z, Gao Y. | 04/2/2022 |
| Silencing of circHIPK3 Inhibits Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction by Sponging miR-185-3p. | Silencing of circHIPK3 Inhibits Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction by Sponging miR-185-3p.
Xu X, Wang J, Wang X., Free PMC Article | 09/25/2021 |
| MicroRNA-185-5p inhibits hepatic gluconeogenesis and reduces fasting blood glucose levels by suppressing G6Pase. | MicroRNA-185-5p inhibits hepatic gluconeogenesis and reduces fasting blood glucose levels by suppressing G6Pase.
Zheng H, Wan J, Shan Y, Song X, Jin J, Su Q, Chen S, Lu X, Yang J, Li Q, Song Y, Li B., Free PMC Article | 08/28/2021 |
| MiR-185-3p downregulates advanced glycosylation end product receptor expression and improves renal function in diabetic nephropathy mice. | MiR-185-3p downregulates advanced glycosylation end product receptor expression and improves renal function in diabetic nephropathy mice.
Xue XX, Lei HQ, Zhao L, Wang XY, Wang Z, Xie LY, Jia JH. | 04/3/2021 |
| MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6. | MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Yuan Q, Xu T, Chen Y, Qu W, Sun D, Liu X, Sun L. | 02/6/2021 |
| Blocking miR-185 expression increases bone formation during osteoporosis, which may partly occur through the regulation of Bgn expression and BMP/Smad signaling. | Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Cui Q, Xing J, Yu M, Wang Y, Xu J, Gu Y, Nan X, Ma W, Liu H, Zhao H., Free PMC Article | 04/25/2020 |
| In mesangial cells from diabetic mice, circRNA_15698/miR-185/TGF-beta1 promoted extracellular matrix-related protein synthesis. | Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR-185/TGF-β1.
Hu W, Han Q, Zhao L, Wang L. | 12/14/2019 |
| suppression of miR-185 targeting PTH could promote osteoblast growth and proliferation during fracture healing through activating Wnt/beta -catenin axis | MicroRNA-185 inhibits the growth and proliferation of osteoblasts in fracture healing by targeting PTH gene through down-regulating Wnt/β -catenin axis: In an animal experiment.
Yao CJ, Lv Y, Zhang CJ, Jin JX, Xu LH, Jiang J, Geng B, Li H, Xia YY, Wu M. | 10/13/2018 |
| Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis. | Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis.
Chang H, Wang Y, Liu H, Nan X, Wong S, Peng S, Gu Y, Zhao H, Feng H., Free PMC Article | 07/28/2018 |
| androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of clear cell renal cell carcinoma through differential regulation of the VEGF-A vs. VEGF-C via miR-185-5p | Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma.
Huang Q, Sun Y, Ma X, Gao Y, Li X, Niu Y, Zhang X, Chang C., Free PMC Article | 02/10/2018 |
| miR-185 controls cholesterol homeostasis as a key posttranscriptional LDLR modulator in hepatic cells, providing novel insight into the regulatory mechanism for LDLR expression and the anti-atherosclerosis effect of miR-185-inhibitor. | microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator.
Jiang H, Zhang J, Du Y, Jia X, Yang F, Si S, Wang L, Hong B. | 09/17/2016 |
| miR-185 has an anti-hypertrophic role in the heart | miR-185 plays an anti-hypertrophic role in the heart via multiple targets in the calcium-signaling pathways.
Kim JO, Song DW, Kwon EJ, Hong SE, Song HK, Min CK, Kim DH., Free PMC Article | 01/30/2016 |
| miR-185 plays an important role in regulating fatty-acid metabolism and cholesterol homeostasis in hepatocytes, as well as in improving insulin sensitivity, both in vitro and in vivo. | MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease.
Wang XC, Zhan XR, Li XY, Yu JJ, Liu XM., Free PMC Article | 09/12/2015 |
| Study determined miR-185 expression in embryonic and adult mouse brains, common and rare variants at this locus were then investigated using a human genetics approach | Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia.
Forstner AJ, Basmanav FB, Mattheisen M, Böhmer AC, Hollegaard MV, Janson E, Strengman E, Priebe L, Degenhardt F, Hoffmann P, Herms S, Maier W, Mössner R, Rujescu D, Ophoff RA, Moebus S, Mortensen PB, Børglum AD, Hougaard DM, Frank J, Witt SH, Rietschel M, Zimmer A, Nöthen MM, Miró X, Cichon S., Free PMC Article | 08/8/2015 |
| a novel axis regulating cholesterol homeostasis exists that exploits miR-185-dependent regulation of SREBP-2 and requires SREBP-1c for function | Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake.
Yang M, Liu W, Pellicane C, Sahyoun C, Joseph BK, Gallo-Ebert C, Donigan M, Pandya D, Giordano C, Bata A, Nickels JT Jr., Free PMC Article | 10/4/2014 |
| miR-185 plays a role in the fine tuned regulation of CRY1 protein expression by controlling the rhythmicity of Cry1 mRNA translation. | MicroRNA-185 oscillation controls circadian amplitude of mouse Cryptochrome 1 via translational regulation.
Lee KH, Kim SH, Lee HR, Kim W, Kim DY, Shin JC, Yoo SH, Kim KT., Free PMC Article | 02/8/2014 |
| miR-185 regulates T cell development through its targeting of several mRNAs including Mzb1. | Transgenic expression of microRNA-185 causes a developmental arrest of T cells by targeting multiple genes including Mzb1.
Belkaya S, Murray SE, Eitson JL, de la Morena MT, Forman JA, van Oers NSC., Free PMC Article | 01/4/2014 |
| Study shows a drastic reduction of miR-185, which resides within the 22q11.2 locus, to levels more than expected by a hemizygous deletion, and demonstrates that this reduction alters dendritic and spine development. | Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion.
Xu B, Hsu PK, Stark KL, Karayiorgou M, Gogos JA., Free PMC Article | 03/23/2013 |