| KRT10 plays an important role in the release of viral genome from endosomes during H9N2 subtype AIV replication in HeLa cells. | KRT10 plays an important role in the release of viral genome from endosomes during H9N2 subtype AIV replication in HeLa cells.
Huang X, Yin G, Zhou B, Cai Y, Hu J, Huang J, Chen Z, Liu Q, Feng X. | 09/6/2023 |
| Effect of mutations on the hydrophobic interactions of the hierarchical molecular structure and mechanical properties of epithelial keratin 1/10. | Effect of mutations on the hydrophobic interactions of the hierarchical molecular structure and mechanical properties of epithelial keratin 1/10.
Huang TL, Chou CC. | 06/25/2022 |
| Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus. | Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus.
Caporali S, Didona B, Paradisi M, Mauriello A, Campione E, Falconi M, Iacovelli F, Minieri M, Pieri M, Bernardini S, Terrinoni A., Free PMC Article | 07/31/2021 |
| Recurrent KRT10 Variant in Ichthyosis with Confetti. | Recurrent KRT10 Variant in Ichthyosis with Confetti.
Takeichi T, Suga Y, Mizuno T, Okuno Y, Ichikawa D, Kono M, Lee JYW, McGrath JA, Akiyama M., Free PMC Article | 06/26/2021 |
| Discovery of heterozygous KRT10 alterations in MAUIE cases underlines the importance of regular skin cancer screening in ichthyosis with confetti. | Discovery of heterozygous KRT10 alterations in MAUIE cases underlines the importance of regular skin cancer screening in ichthyosis with confetti.
Burger B, Ghosh A, Ng CKY, Piscuoglio S, Spoerri I, Itin PH, Greer K, Elbaum D. | 06/12/2021 |
| Ozone therapy promotes the differentiation of basal keratinocytes via increasing Tp63-mediated transcription of KRT10 to improve psoriasis. | Ozone therapy promotes the differentiation of basal keratinocytes via increasing Tp63-mediated transcription of KRT10 to improve psoriasis.
Gao L, Dou J, Zhang B, Zeng J, Cheng Q, Lei L, Tan L, Zeng Q, Ding S, Guo A, Cheng H, Yang C, Luo Z, Lu J., Free PMC Article | 05/1/2021 |
| Ichthyosis with confetti caused by new and recurrent mutations in KRT10 associated with varying degrees of keratin 10 mis-localization. | Ichthyosis with confetti caused by new and recurrent mutations in KRT10 associated with varying degrees of keratin 10 mis-localization.
Pan Y, Feng C, Wang H, Lee M, Tang Z, Lin Z. | 04/3/2021 |
| Mutations in KRT10 in epidermolytic acanthoma. | Mutations in KRT10 in epidermolytic acanthoma.
Cheraghlou S, Atzmony L, Roy SF, McNiff JM, Choate KA., Free PMC Article | 03/6/2021 |
| Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes. | Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes.
Aldehlawi H, Usman S, Lalli A, Ahmad F, Williams G, Teh MT, Waseem A., Free PMC Article | 12/12/2020 |
| The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells. | The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells.
Kim J, Villadsen R., Free PMC Article | 12/12/2020 |
| Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti. | Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti.
Renz P, Imahorn E, Spoerri I, Aushev M, March OP, Wariwoda H, Von Arb S, Volz A, Itin PH, Reichelt J, Burger B., Free PMC Article | 09/26/2020 |
| The Keratin 1-keratin 10-1B knob/pocket mechanism is conserved across keratins and many non-keratin intermediate filaments.Light scattering and circular dichroism measurements demonstrated enhanced aggregation of K1(S233L)/K10-1B in solution without affecting secondary structure. The K1(S233L)/K10-1B octamer structure revealed S233L(K1) causes aberrant hydrophobic interactions between 1B tetramers. | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Eldirany SA, Ho M, Hinbest AJ, Lomakin IB, Bunick CG., Free PMC Article | 01/11/2020 |
| These findings indicate that alpha112:alpha556 (IV) network, which is the only network that includes the alpha6(IV) chain, is one regulator of KRT10 expression in keratinization of oral mucosal epithelium. | Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.
Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Kimura-Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T., Free PMC Article | 08/24/2019 |
| Results showed identical expression pattern for KRT1 and KRT10, their expression was higher in pediatric cases than in adults, especially in pediatric recurrent samples. | Analysis of KRT1, KRT10, KRT19, TP53 and MMP9 expression in pediatric and adult cholesteatoma.
Palkó E, Póliska S, Sziklai I, Penyige A., Free PMC Article | 01/26/2019 |
| The molecular diagnostics by the whole exome sequencing showed a novel de novo (c.1374-2A>C) mutation in the KRT10 gene responsible for the development of IWC (KRT10 defect was confirmed by immunofluorescent study). Concurrently, the m.14484T>C mutation in mitochondrial MTND6 gene (characteristic for Leber's hereditary optic neuropathy or LHON) was detected in patient, his mother and brother | Coexistence of mutations in keratin 10 (KRT10) and the mitochondrial genome in a patient with ichthyosis with confetti and Leber's hereditary optic neuropathy.
Kalinska-Bienias A, Pollak A, Kowalewski C, Lechowicz U, Stawinski P, Gergont A, Kosinska J, Pronicka E, Kowalski P, Wozniak K, Ploski R. | 06/9/2018 |
| Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions. | In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses.
Banerjee S, Wu Q, Ying Y, Li Y, Shirota M, Neculai D, Li C., Free PMC Article | 02/3/2018 |
| KRT10 gene mutation was present in all of the affected individuals, but absent in the five unaffected and 100 ethnically-matched healthy controls. | Ichthyosis hystrix Lambert type and Curth-Macklin type are a single entity with affected (KRT1 mutation) or unaffected (KRT10 mutation) palms and soles?
Wang WH, Zhang L, Li LF, Sun TT. | 06/24/2017 |
| Mutations in the highly conserved helix initiation motif of K10 were associated with mild or severe form of epidermolytic ichthyosis | S159P mutation of keratin 10 gene causes severe form of epidermolytic hyperkeratosis.
Chen PJ, Li CX, Wen J, Peng YS, Zeng K, Zhang SQ, Tian X, Zhang XB. | 04/22/2017 |
| Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis. | Extensive Post-zygotic Mosaicism of KRT1 or KRT10 Mutation Mimicking Classical Epider-molytic Ichthyosis.
Severino-Freire M, Jonca N, Pichery M, Tournier E, Chassaing N, Mazereeuw-Hautier J. | 03/25/2017 |
| Report genetic/clinical spectrum of KRT10 mutations in keratinopathic ichthyosis. | Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.
Hotz A, Oji V, Bourrat E, Jonca N, Mazereeuw-Hautier J, Betz RC, Blume-Peytavi U, Stieler K, Morice-Picard F, Schönbuchner I, Markus S, Schlipf N, Fischer J. | 01/28/2017 |
| We present an autosomal dominant pedigree with epidermolytic ichthyosis resulting from a new heterozygous missense mutation in keratin 10. | Intrafamilial phenotypic heterogeneity of epidermolytic ichthyosis associated with a new missense mutation in keratin 10.
Abdul-Wahab A, Takeichi T, Liu L, Stephens C, Akiyama M, McGrath JA. | 01/14/2017 |
| Complete structure of an epithelial keratin 1/keratin 10 dimer has been presented. | Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.
Bray DJ, Walsh TR, Noro MG, Notman R., Free PMC Article | 04/23/2016 |
| recombinant adenovirus-mediated overexpression of KRT10 and PTEN may improve the cisplatin resistance of ovarian cancer in vitro and in vivo | Recombinant adenovirus-mediated overexpression of PTEN and KRT10 improves cisplatin resistance of ovarian cancer in vitro and in vivo.
Wu H, Wang K, Liu W, Hao Q. | 03/26/2016 |
| findings provide structural insights into phenotypic variation in epidermolytic ichthyosis due to KRT10 mutations | Mutations Affecting Keratin 10 Surface-Exposed Residues Highlight the Structural Basis of Phenotypic Variation in Epidermolytic Ichthyosis.
Mirza H, Kumar A, Craiglow BG, Zhou J, Saraceni C, Torbeck R, Ragsdale B, Rehder P, Ranki A, Choate KA. | 03/5/2016 |
| The diagnosis of ichthyosis with confetti was confirmed by the identification of 2 previously unreported mutations in intron 6 and exon 7 of KRT10. | Early immunopathological diagnosis of ichthyosis with confetti in two sporadic cases with new mutations in keratin 10.
Diociaiuti A, Fortugno P, El Hachem M, Angelo C, Proto V, De Luca N, Martinelli D, Boldrini R, Castiglia D, Zambruno G. | 11/7/2015 |