| Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis. | Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis.
Moye AL, Dost AF, Ietswaart R, Sengupta S, Ya V, Aluya C, Fahey CG, Louie SM, Paschini M, Kim CF., Free PMC Article | 08/13/2024 |
| Molecular Mechanism of Phosphorylation-Mediated Impacts on the Conformation Dynamics of GTP-Bound KRAS Probed by GaMD Trajectory-Based Deep Learning. | Molecular Mechanism of Phosphorylation-Mediated Impacts on the Conformation Dynamics of GTP-Bound KRAS Probed by GaMD Trajectory-Based Deep Learning.
Chen J, Wang J, Yang W, Zhao L, Zhao J, Hu G., Free PMC Article | 08/13/2024 |
| KRAS and BRAF genetic alterations in lung cancer: A case - control study. | KRAS and BRAF genetic alterations in lung cancer: A case - control study.
Sawal HA, Shah SI, Malik SS, Mehmood S, Baig M, Rasool E, Masood N. | 08/5/2024 |
| KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways. | KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways.
Mondal K, Posa MK, Shenoy RP, Roychoudhury S., Free PMC Article | 08/1/2024 |
| Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. | Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex.
Damianou A, Liang Z, Lassen F, Vendrell I, Vere G, Hester S, Charles PD, Pinto-Fernandez A, Santos A, Fischer R, Kessler BM., Free PMC Article | 08/1/2024 |
| KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis. | KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME., Free PMC Article | 07/31/2024 |
| Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells. | Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells.
Hindul NL, Abbott LR, Adan SMD, Straatman KR, Fry AM, Hirota K, Tanaka K., Free PMC Article | 07/24/2024 |
| The correlation between KRAS and TP53 gene mutations and early growth of pulmonary nodules. | The correlation between KRAS and TP53 gene mutations and early growth of pulmonary nodules.
Zhao B, Li B, Guo H, Zhao Q, Zhang X, Zhao H, Xue W, Li W, Duan G, Xu S., Free PMC Article | 07/16/2024 |
| An Updated Review on KRAS Mutation in Lung Cancer (NSCLC) and Its Effects on Human Health. | An Updated Review on KRAS Mutation in Lung Cancer (NSCLC) and Its Effects on Human Health.
Ghosh S, Bhuniya T, Dey A, Koley M, Roy P, Bera A, Gol D, Chowdhury A, Chowdhury R, Sen S. | 07/15/2024 |
| Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer. | Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer.
Wang R, Khatpe AS, Kumar B, Mang HE, Batic K, Adebayo AK, Nakshatri H., Free PMC Article | 07/15/2024 |
| Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. | Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes.
Alanazi M, Weng T, McLeod L, Gearing LJ, Smith JA, Kumar B, Saad MI, Jenkins BJ., Free PMC Article | 07/8/2024 |
| KRAS, NRAS and BRAF Mutational Profile of Colorectal Cancer in a Series of Moroccan Patients. | KRAS, NRAS and BRAF Mutational Profile of Colorectal Cancer in a Series of Moroccan Patients.
El Zaitouni S, Laraqui A, Ghaouti M, Benzekri A, Kettani F, Bajjou T, Sekhsokh Y, Benmokhtar S, Jafari M, Baba W, Oukabli M, El Annaz H, Abi R, Tagajdid MR, El Kochri S, Lahlou IA, Ameziane El Hassani R, Ennibi K., Free PMC Article | 06/28/2024 |
| Deep neural network for the prediction of KRAS, NRAS, and BRAF genotypes in left-sided colorectal cancer based on histopathologic images. | Deep neural network for the prediction of KRAS, NRAS, and BRAF genotypes in left-sided colorectal cancer based on histopathologic images.
Li X, Chi X, Huang P, Liang Q, Liu J. | 06/10/2024 |
| KRAS depletion suppresses ferroptosis and affects Hippo pathway in cataract. | KRAS depletion suppresses ferroptosis and affects Hippo pathway in cataract.
Jiang H, Yu Y, Yan Y. | 06/7/2024 |
| Genomic analysis of primary epithelial neoplasms of the seminal vesicle identifies a subset of mucinous cystic tumours driven by KRAS mutations. | Genomic analysis of primary epithelial neoplasms of the seminal vesicle identifies a subset of mucinous cystic tumours driven by KRAS mutations.
Collins K, Galea LA, Foroughi F, Siegmund SE, Anderson WJ, Appu S, Idrees MT, Ulbright TM, Acosta AM. | 05/13/2024 |
| Identification of KRAS mutation-associated gut microbiota in colorectal cancer and construction of predictive machine learning model. | Identification of KRAS mutation-associated gut microbiota in colorectal cancer and construction of predictive machine learning model.
Huang Z, Huang X, Huang Y, Liang K, Chen L, Zhong C, Chen Y, Chen C, Wang Z, He F, Qin M, Long C, Tang B, Huang Y, Wu Y, Mo X, Weizhong T, Liu J., Free PMC Article | 05/7/2024 |
| KRAS mutations in pancreatic cancer: could we talk about a risk factor for the development of thromboembolic phenomena? | KRAS mutations in pancreatic cancer: could we talk about a risk factor for the development of thromboembolic phenomena?
Gutiérrez Pérez C, Blanco Abad C, Hontoria Bautista G, Saiz López P, Rodríguez Ledesma I, Espinosa Cabria N, Ramos Reguera I, López Muñoz AM. | 05/6/2024 |
| The Effect of RAS/BRAF Mutation Status on Prognosis and Relapse Pattern in Early Stage Colon Cancers. | The Effect of RAS/BRAF Mutation Status on Prognosis and Relapse Pattern in Early Stage Colon Cancers.
Kunt N, Araz M, Yildirim MS, Findik S, Kocak MZ, Eryilmaz MK, Artac M. | 04/18/2024 |
| Circular RNAs in the KRAS pathway: Emerging players in cancer progression. | Circular RNAs in the KRAS pathway: Emerging players in cancer progression.
Hussain MS, Moglad E, Afzal M, Bansal P, Kaur H, Deorari M, Ali H, Shahwan M, Hassan Almalki W, Kazmi I, Alzarea SI, Singh SK, Dua K, Gupta G. | 04/16/2024 |
| Impact of the STK11/KRAS co-mutation on the response to immunotherapy in a real-world pan-cancer cohort. | Impact of the STK11/KRAS co-mutation on the response to immunotherapy in a real-world pan-cancer cohort.
Olsen A, Lebedeva A, Nosova P, Nikulin V, Sharova M, Ignatova E, Mileyko V, Ivanov M. | 04/16/2024 |
| Epidemiological and clinicopathological features of KRAS, NRAS, BRAF mutations and MSI in Chinese patients with stage I-III colorectal cancer. | Epidemiological and clinicopathological features of KRAS, NRAS, BRAF mutations and MSI in Chinese patients with stage I-III colorectal cancer.
Wang W, Wang R, Han X, Zhang W, Zhu L, Gu Y., Free PMC Article | 04/16/2024 |
| STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer. | STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer.
D'Amico S, Kirillov V, Petrenko O, Reich NC., Free PMC Article | 04/12/2024 |
| KRAS mutations, autoimmunity and female sex in chronic myelomonocytic leukemia. | KRAS mutations, autoimmunity and female sex in chronic myelomonocytic leukemia.
Osman AEG, Rets A, Patel AB. | 03/21/2024 |
| Activation of KrasG12D in Subset of Alveolar Type II Cells Enhances Cellular Plasticity in Lung Adenocarcinoma. | Activation of KrasG12D in Subset of Alveolar Type II Cells Enhances Cellular Plasticity in Lung Adenocarcinoma.
Chaudhary P, Xu X, Wang G, Hoj JP, Rampersad RR, Asselin-Labat ML, Ting S, Kim W, Tamayo P, Pendergast AM, Onaitis MW., Free PMC Article | 03/15/2024 |
| Transcriptome sequencing analysis reveals miR-30c-5p promotes ferroptosis in cervical cancer and inhibits growth and metastasis of cervical cancer xenografts by targeting the METTL3/KRAS axis. | Transcriptome sequencing analysis reveals miR-30c-5p promotes ferroptosis in cervical cancer and inhibits growth and metastasis of cervical cancer xenografts by targeting the METTL3/KRAS axis.
Gong Y, Luo G, Zhang S, Chen Y, Hu Y. | 03/14/2024 |