| The interaction between S100A2 and KPNA2 mediates NFYA nuclear import and is a novel therapeutic target for colorectal cancer metastasis. | The interaction between S100A2 and KPNA2 mediates NFYA nuclear import and is a novel therapeutic target for colorectal cancer metastasis.
Han F, Zhang L, Liao S, Zhang Y, Qian L, Hou F, Gong J, Lai M, Zhang H. | 08/11/2024 |
| Mutational analysis of SARS-CoV-2 ORF6-KPNA2 binding interface and identification of potent small molecule inhibitors to recuse the host immune system. | Mutational analysis of SARS-CoV-2 ORF6-KPNA2 binding interface and identification of potent small molecule inhibitors to recuse the host immune system.
Suleman M, Said A, Khan H, Rehman SU, Alshammari A, Crovella S, Yassine HM., Free PMC Article | 03/1/2024 |
| Analysis of the effects of importin alpha1 on the nuclear translocation of IL-1alpha in HeLa cells. | Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells.
Yamada A, Wake K, Imaoka S, Motoyoshi M, Yamamoto T, Asano M., Free PMC Article | 02/16/2024 |
| Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression. | Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression.
Zeng Q, Feng K, Yu Y, Lv Y. | 11/22/2023 |
| MiR-101-3p targets KPNA2 to inhibit the progression of lung squamous cell carcinoma cell lines. | MiR-101-3p targets KPNA2 to inhibit the progression of lung squamous cell carcinoma cell lines.
Dong L, Jiang H, Qiu T, Xu Y, Chen E, Huang A, Ying K. | 11/6/2023 |
| ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. | ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling.
Chen Y, Li J, Ma J, Bao Y., Free PMC Article | 07/12/2023 |
| Novel roles of karyopherin subunit alpha 2 in hepatocellular carcinoma. | Novel roles of karyopherin subunit alpha 2 in hepatocellular carcinoma.
Yang X, Wang H, Zhang L, Yao S, Dai J, Wen G, An J, Jin H, Du Q, Hu Y, Zheng L, Chen X, Yi Z, Tuo B. | 06/1/2023 |
| KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation. | KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation.
Jia Y, Wang Q, Liang M, Huang K., Free PMC Article | 01/11/2023 |
| Long noncoding RNA TUG1 decreases bladder cancer chemo-sensitivity toward doxorubicin through elevating KPNA2 expression and activating the PI3K/AKT pathway via adsorbing miR-582-5p. | Long noncoding RNA TUG1 decreases bladder cancer chemo-sensitivity toward doxorubicin through elevating KPNA2 expression and activating the PI3K/AKT pathway via adsorbing miR-582-5p.
Lu P, Jiang Y, Xia Z. | 12/24/2022 |
| CREB1 regulates KPNA2 by inhibiting mir-495-3p transcription to control melanoma progression : The role of the CREB1/miR-495-3p/KPNA2 axis in melanoma progression. | CREB1 regulates KPNA2 by inhibiting mir-495-3p transcription to control melanoma progression : The role of the CREB1/miR-495-3p/KPNA2 axis in melanoma progression.
Geng X, Qiu X, Gao J, Gong Z, Zhou X, Liu C, Luo H., Free PMC Article | 12/24/2022 |
| Decreased Expression of Karyopherin-alpha 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. | Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells.
Jiang L, Li D, Wang C, Liao J, Liu J, Wei Q, Wang Y., Free PMC Article | 08/27/2022 |
| Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets. | Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets.
Alnoumas L, van den Driest L, Apczynski Z, Lannigan A, Johnson CH, Rattray NJW, Rattray Z., Free PMC Article | 08/27/2022 |
| Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein. | Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein.
Song Y, Zhang H, Wang Y, Guo J, Tang S, Wang L, Peng K, Dong CS. | 05/7/2022 |
| MiR-101-3p Suppresses Progression of Cervical Squamous Cell Carcinoma by Targeting and Down-Regulating KPNA2. | MiR-101-3p Suppresses Progression of Cervical Squamous Cell Carcinoma by Targeting and Down-Regulating KPNA2.
Wang H, Xiao R, Yang B., Free PMC Article | 03/12/2022 |
| KPNA2 promotes renal cell carcinoma proliferation and metastasis via NPM. | KPNA2 promotes renal cell carcinoma proliferation and metastasis via NPM.
Zheng S, Li X, Deng T, Liu R, Bai J, Zuo T, Guo Y, Chen J., Free PMC Article | 02/19/2022 |
| Oncogenic role of karyopherin alpha2 (KPNA2) in human tumors: A pan-cancer analysis. | Oncogenic role of karyopherin α2 (KPNA2) in human tumors: A pan-cancer analysis.
Sun Y, Li W, Li X, Zheng H, Qiu Y, Yang H. | 02/5/2022 |
| Nuclear accumulation of KPNA2 impacts radioresistance through positive regulation of the PLSCR1-STAT1 loop in lung adenocarcinoma. | Nuclear accumulation of KPNA2 impacts radioresistance through positive regulation of the PLSCR1-STAT1 loop in lung adenocarcinoma.
Liao WC, Lin TJ, Liu YC, Wei YS, Chen GY, Feng HP, Chang YF, Chang HT, Wang CL, Chi HC, Wang CI, Lin KH, Ou Yang WT, Yu CJ., Free PMC Article | 01/15/2022 |
| Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). | Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2).
Liang YC, Su Q, Liu YJ, Xiao H, Yin HZ. | 12/11/2021 |
| Increased expression of KPNA2 predicts unfavorable prognosis in ovarian cancer patients, possibly by targeting KIF4A signaling. | Increased expression of KPNA2 predicts unfavorable prognosis in ovarian cancer patients, possibly by targeting KIF4A signaling.
Cui X, Wang H, Wu X, Huo K, Jing X., Free PMC Article | 11/22/2021 |
| Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC. | Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC.
Zhou KX, Huang S, Hu LP, Zhang XL, Qin WT, Zhang YL, Yao LL, Yu Y, Zhou YQ, Zhu L, Ji J, Zhang ZG., Free PMC Article | 11/6/2021 |
| Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy. | Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy.
He J, Yang L, Chang P, Yang S, Lin S, Tang Q, Wang X, Zhang YJ., Free PMC Article | 10/2/2021 |
| KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway. | KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway.
Zeng F, Luo L, Li D, Guo J, Guo M., Free PMC Article | 08/28/2021 |
| High expression of KPNA2 promotes colorectal cancer development by activating the PI3K/AKT pathway. | High expression of KPNA2 promotes colorectal cancer development by activating the PI3K/AKT pathway.
Huang B, Luo H, Guo XB. | 02/13/2021 |
| USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2. | USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2.
Cai Z, Zhang MX, Tang Z, Zhang Q, Ye J, Xiong TC, Zhang ZD, Zhong B., Free PMC Article | 12/26/2020 |
| KPNA2/ERG Coexpression is Associated With Early Recurrence in Advanced Prostate Cancers. | KPNA2/ERG Coexpression is Associated With Early Recurrence in Advanced Prostate Cancers.
D'Antonio A, Caputo A, Fraggetta F, Pepe P, Insabato L, Barra E, Barresi V, Altieri V, Greco U, Savastano R, Zeppa P. | 11/28/2020 |