Eg5 UFMylation promotes spindle organization during mitosis. | Eg5 UFMylation promotes spindle organization during mitosis. Li G, Huang Y, Han W, Wei L, Huang H, Zhu Y, Xiao Q, Wang Z, Huang W, Duan R., Free PMC Article | 09/10/2024 |
Mitotic Functions and Characters of KIF11 in Cancers. | Mitotic Functions and Characters of KIF11 in Cancers. Gao W, Lu J, Yang Z, Li E, Cao Y, Xie L., Free PMC Article | 05/11/2024 |
Human kinesin-5 KIF11 drives the helical motion of anti-parallel and parallel microtubules around each other. | Human kinesin-5 KIF11 drives the helical motion of anti-parallel and parallel microtubules around each other. Meißner L, Niese L, Schüring I, Mitra A, Diez S., Free PMC Article | 04/5/2024 |
KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia. | KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia. Zhu L, Chen C, Kang M, Ma X, Sun X, Xue Y, Fang Y., Free PMC Article | 11/6/2023 |
UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination. | UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination. Qi X, Liu Y, Peng Y, Fu Y, Fu Y, Yin L, Li X., Free PMC Article | 09/21/2023 |
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11. | ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11. Fang Q, Li Q, Qi Y, Pan Z, Feng T, Xin W. | 06/16/2023 |
Whole exome sequencing revealed novel pathogenic variants in Vietnamese patients with FEVR. | Whole exome sequencing revealed novel pathogenic variants in Vietnamese patients with FEVR. Trang DT, Phu NM, Hung DM, Nhung VP, Ha NN, Thuong MTH, Ngoc TTB, Hiep NX, Ton ND, Hai NV, Ha NH., Free PMC Article | 05/5/2023 |
KIF11 As a Potential Pan-Cancer Immunological Biomarker Encompassing the Disease Staging, Prognoses, Tumor Microenvironment, and Therapeutic Responses. | KIF11 As a Potential Pan-Cancer Immunological Biomarker Encompassing the Disease Staging, Prognoses, Tumor Microenvironment, and Therapeutic Responses. Guo X, Zhou L, Wu Y, Li J., Free PMC Article | 02/9/2023 |
A non-mitotic role for Eg5 in regulating cilium formation and sonic hedgehog signaling. | A non-mitotic role for Eg5 in regulating cilium formation and sonic hedgehog signaling. Ran J, Li H, Zhang Y, Yu F, Yang Y, Nie C, Yang S, Li D, Zhou J, Liu M. | 01/28/2023 |
Overexpression of kif11 is a poor prognostic factor in clear cell renal cell carcinoma. | Overexpression of kif11 is a poor prognostic factor in clear cell renal cell carcinoma. Kowalewski A, Jaworski D, Antosik P, Smolińska M, Ligmanowska J, Grzanka D, Szylberg Ł. | 11/19/2022 |
KIF11 manipulates SREBP2-dependent mevalonate cross talk to promote tumor progression in pancreatic ductal adenocarcinoma. | KIF11 manipulates SREBP2-dependent mevalonate cross talk to promote tumor progression in pancreatic ductal adenocarcinoma. Gu X, Zhu Q, Tian G, Song W, Wang T, Wang A, Chen X, Qin S., Free PMC Article | 10/1/2022 |
Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability. | Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability. Dale KL, Armond JW, Hynds RE, Vladimirou E., Free PMC Article | 09/3/2022 |
Coarse grained modelling highlights the binding differences in the two different allosteric sites of the Human Kinesin EG5 and its implications in inhibitor design. | Coarse grained modelling highlights the binding differences in the two different allosteric sites of the Human Kinesin EG5 and its implications in inhibitor design. Alexandar SP, Yennamalli RM, Ulaganathan V. | 08/13/2022 |
Upregulation of KIF11 in TP53 Mutant Glioma Promotes Tumor Stemness and Drug Resistance. | Upregulation of KIF11 in TP53 Mutant Glioma Promotes Tumor Stemness and Drug Resistance. Liu B, Zhang G, Cui S, Du G. | 06/11/2022 |
Update on the Phenotypic and Genotypic Spectrum of KIF11-Related Retinopathy. | Update on the Phenotypic and Genotypic Spectrum of KIF11-Related Retinopathy. Wang Y, Zhang Z, Huang L, Sun L, Li S, Zhang T, Ding X., Free PMC Article | 04/30/2022 |
Severe Exudative Vitreoretinopathy as a Common Feature for CTNNB1, KIF11 and NDP Variants Plus Sector Degeneration for KIF11. | Severe Exudative Vitreoretinopathy as a Common Feature for CTNNB1, KIF11 and NDP Variants Plus Sector Degeneration for KIF11. Yang J, Xiao X, Li S, Mai G, Jia X, Wang P, Sun W, Zhang Q. | 04/16/2022 |
KIF11 as a potential cancer prognostic marker promotes tumorigenesis in children with Wilms tumor. | KIF11 as a potential cancer prognostic marker promotes tumorigenesis in children with Wilms tumor. Luo Y, Liu W, Zhu Y, Tian Y, Wu K, Ji L, Ding L, Zhang W, Gao T, Liu X, Zhao J. | 03/19/2022 |
The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models. | The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models. Masanas M, Masiá N, Suárez-Cabrera L, Olivan M, Soriano A, Majem B, Devis-Jauregui L, Burgos-Panadero R, Jiménez C, Rodriguez-Sodupe P, Boloix A, Toledano I, Guillén G, Navarro A, Llobet-Navas D, Villanueva A, Sánchez de Toledo J, Roma J, Noguera R, Moreno L, Krauss R, Gallego S, Santamaria A, Segura MF., Free PMC Article | 02/26/2022 |
High KIF11 expression is associated with poor outcome of NSCLC. | High KIF11 expression is associated with poor outcome of NSCLC. Liu J, Tian Y, Yi L, Gao Z, Lou M, Yuan K. | 02/19/2022 |
KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer. | KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer. Ling J, Wang Y, Ma L, Zheng Y, Tang H, Meng L, Zhang L. | 02/12/2022 |
Five novel copy number variations detected in patients with familial exudative vitreoretinopathy. | Five novel copy number variations detected in patients with familial exudative vitreoretinopathy. Luo J, Li J, Zhang X, Li JK, Chen HJ, Zhao PQ, Fei P., Free PMC Article | 01/22/2022 |
KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer. | KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer. Wei D, Rui B, Qingquan F, Chen C, Ping HY, Xiaoling S, Hao W, Jun G., Free PMC Article | 01/15/2022 |
Identification of a novel mutation in KIF11 with functional analysis in a cohort of 516 familial patients with exudative vitreoretinopathy. | Identification of a novel mutation in KIF11 with functional analysis in a cohort of 516 familial patients with exudative vitreoretinopathy. Wang K, Zhang X, Tian T, Zhao P., Free PMC Article | 01/1/2022 |
Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers. | Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers. Murase Y, Ono H, Ogawa K, Yoshioka R, Ishikawa Y, Ueda H, Akahoshi K, Ban D, Kudo A, Tanaka S, Tanabe M., Free PMC Article | 11/27/2021 |
Prognostic Impact and Functional Annotations of KIF11 and KIF14 Expression in Patients with Colorectal Cancer. | Prognostic Impact and Functional Annotations of KIF11 and KIF14 Expression in Patients with Colorectal Cancer. Neska-Długosz I, Buchholz K, Durślewicz J, Gagat M, Grzanka D, Tojek K, Klimaszewska-Wiśniewska A., Free PMC Article | 10/30/2021 |