| CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma. | CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma.
Hong P, Xu T, Xu J, Chen W, Hu H, Chen J, Li L, Zheng C, Li B, Liu J, Dai W, Li E, Zhang F, Xu W. | 06/27/2024 |
| ARF6 promotes Streptococcus suis suilysin induced apoptosis in HBMECs. | ARF6 promotes Streptococcus suis suilysin induced apoptosis in HBMECs.
Jiang C, Zhou P, Zhang X, Ma N, Hu Y, Zhang M, Ghonaim AH, Li H, Dong L, Zeng W, Li C, Lang Y, Sun Y, He Q, Li W. | 06/11/2024 |
| HUNK inhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6. | HUNK inhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6.
Jiang S, Han X, Liu T, He Y, Zhao Z, Liu T, Cheng S, Zhang J, Duan L, Liu Y, Cheng T, Liu Y, Ye Q, Gao S. | 01/16/2024 |
| Enterovirus 71 enters human brain microvascular endothelial cells through an ARF6-mediated endocytic pathway. | Enterovirus 71 enters human brain microvascular endothelial cells through an ARF6-mediated endocytic pathway.
Zhu Y, Wang X, He Z, Zhao P, Ren H, Qi Z. | 07/12/2023 |
| ARF6 is a host factor for SARS-CoV-2 infection in vitro. | ARF6 is a host factor for SARS-CoV-2 infection in vitro.
Mirabelli C, Bragazzi Cunha J, Wotring JW, Sherman EJ, El Saghir J, Harder J, Kretzler M, Sexton JZ, Emmer BT, Wobus CE., Free PMC Article | 06/26/2023 |
| Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes. | Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes.
Dou D, Smith EM, Evans CS, Boecker CA, Holzbaur ELF., Free PMC Article | 06/7/2023 |
| KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion. | KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion.
Sabe H., Free PMC Article | 05/15/2023 |
| Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion. | Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion.
Harms J, Lüttgenau SM, Emming C, Guske J, Weber K, Wagner T, Schowe L, Nedvetsky P, Krahn MP., Free PMC Article | 03/19/2023 |
| A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression. | A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression.
Xiao B, Zhang Y, Lu Z, Chen W, An Y, Zu G, Xu X, Wu D, Yang H, Qin Y, Chen X., Free PMC Article | 12/31/2022 |
| LncRNA FOXD3-AS1 promotes breast cancer progression by mediating ARF6. | LncRNA FOXD3-AS1 promotes breast cancer progression by mediating ARF6.
Zhang X, Zhao X, Chang L, Liu F, Li C, Ge P. | 08/27/2022 |
| [Arf6 regulates endometriotic epithelial-mesenchymal transition and mitochondrial distribution]. | [Arf6 regulates endometriotic epithelial-mesenchymal transition and mitochondrial distribution].
Chen YC, Wang QM, Chen L, Zhu MH, Zhang J. | 07/16/2022 |
| Activation of the GTPase ARF6 regulates invasion of human vascular smooth muscle cells by stimulating MMP14 activity. | Activation of the GTPase ARF6 regulates invasion of human vascular smooth muscle cells by stimulating MMP14 activity.
Fiola-Masson E, Artigalas J, Campbell S, Claing A., Free PMC Article | 06/18/2022 |
| DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6. | DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6.
Zhang X, Hu Y, Pan Y, Xiong Y, Zhang Y, Han M, Dong K, Song J, Liang H, Ding Z, Zhang X, Zhu H, Liu Q, Lu X, Feng Y, Chen X, Zhang Z, Zhang B., Free PMC Article | 05/7/2022 |
| Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6. | Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6.
Lüttgenau SM, Emming C, Wagner T, Harms J, Guske J, Weber K, Neugebauer U, Schröter R, Panichkina O, Pethő Z, Weber F, Schwab A, Wege AK, Nedvetsky P, Krahn MP., Free PMC Article | 01/15/2022 |
| ADP Ribosylation Factor 6 Promotes Contraction and Proliferation, Suppresses Apoptosis and Is Specifically Inhibited by NAV2729 in Prostate Stromal Cells. | ADP Ribosylation Factor 6 Promotes Contraction and Proliferation, Suppresses Apoptosis and Is Specifically Inhibited by NAV2729 in Prostate Stromal Cells.
Wang R, Schneider S, Keppler OT, Li B, Rutz B, Ciotkowska A, Stief CG, Hennenberg M. | 11/13/2021 |
| ARF6 and Rab11 as intrinsic regulators of axon regeneration. | ARF6 and Rab11 as intrinsic regulators of axon regeneration.
Nieuwenhuis B, Eva R., Free PMC Article | 07/17/2021 |
| ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1. | ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1.
Chan WWR, Li W, Chang RCC, Lau KF. | 04/24/2021 |
| Chlortetracycline, a Novel Arf Inhibitor That Decreases the Arf6-Dependent Invasive Properties of Breast Cancer Cells. | Chlortetracycline, a Novel Arf Inhibitor That Decreases the Arf6-Dependent Invasive Properties of Breast Cancer Cells.
Macia E, Vazquez-Rojas M, Robiolo A, Fayad R, Abélanet S, Mus-Veteau I, Fontaine-Vive F, Mehiri M, Luton F, Franco M., Free PMC Article | 04/13/2021 |
| The small GTPase ARF6 regulates GABAergic synapse development. | The small GTPase ARF6 regulates GABAergic synapse development.
Kim H, Jung H, Jung H, Kwon SK, Ko J, Um JW., Free PMC Article | 02/13/2021 |
| MicroRNA-145 suppresses cell migration and invasion in upper tract urothelial carcinoma by targeting ARF6. | MicroRNA-145 suppresses cell migration and invasion in upper tract urothelial carcinoma by targeting ARF6.
Hsu WC, Li WM, Lee YC, Huang AM, Chang LL, Lin HH, Wu WJ, Li CC, Liang PI, Ke HL. | 01/23/2021 |
| Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization. | Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization.
Ren C, Yuan Q, Jian X, Randazzo PA, Tang W, Wu D., Free PMC Article | 09/26/2020 |
| Depletion of Arf6 compromises cross-presentation of immune complexes but not of soluble, phagocytosed or mannose receptor-targeted antigen, suggesting a role of Fc receptor-regulated Arf6 trafficking in cross-presentation of immune complexes. | The role of MHC class I recycling and Arf6 in cross-presentation by murine dendritic cells.
Montealegre S, Abramova A, Manceau V, de Kanter AF, van Endert P., Free PMC Article | 07/25/2020 |
| Despite Iqsec2 normally acting to activate Arf6 substrate, authors demonstrate that mice modelling the loss of Iqsec2 function present with increased levels of activated Arf6. Authors contend that loss of Iqsec2 function leads to altered regulation of activated Arf6-mediated responses to synaptic signalling and immature synaptic networks. | Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females.
Jackson MR, Loring KE, Homan CC, Thai MH, Määttänen L, Arvio M, Jarvela I, Shaw M, Gardner A, Gecz J, Shoubridge C., Free PMC Article | 06/27/2020 |
| A novel redox-sensitive APE1-ARF6-MMP-14 signaling axis that mediates cellular invasion in esophageal adenocarcinoma.APE1 promotes ARF6 activity via interaction and redox function. | APE1 Upregulates MMP-14 via Redox-Sensitive ARF6-Mediated Recycling to Promote Cell Invasion of Esophageal Adenocarcinoma.
Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Yan J, Robbins DJ, Washington MK, Belkhiri A, El-Rifai W., Free PMC Article | 06/20/2020 |
| High glucose-induced cholesterol accumulation and cellular injury in podocytes may be related to the recycling disorder of ABCA1 caused by the downexpression of Arf6 in diabetic kidney disease. | Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
Hu J, Yang Q, Chen Z, Liang W, Feng J, Ding G. | 06/13/2020 |