Novel Germline KIT Variants in Families With Severe Piebaldism: Case Series and Literature Review. | Novel Germline KIT Variants in Families With Severe Piebaldism: Case Series and Literature Review. Zhang Y, Gao H, Zhang L, Zhao Y, Qiu C, Liu X., Free PMC Article | 08/5/2024 |
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. | KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Mühlenberg T, Falkenhorst J, Schulz T, Fletcher BS, Teuber A, Krzeciesa D, Klooster I, Lundberg M, Wilson L, Lategahn J, von Mehren M, Grunewald S, Tüns AI, Wardelmann E, Sicklick JK, Brahmi M, Serrano C, Schildhaus HU, Sievers S, Treckmann J, Heinrich MC, Raut CP, Ou WB, Marino-Enriquez A, George S, Rauh D, Fletcher JA, Bauer S., | 04/30/2024 |
Elevated c-kit expression in failed autologous arteriovenous fistulas in end-stage renal disease patients. | Elevated c-kit expression in failed autologous arteriovenous fistulas in end-stage renal disease patients. Du J, Li Y, Jia X, Kong X, Liang L, Wang D, Li A, Chen Q, Su H, Li W, Xu D. | 03/14/2024 |
Molecular and clinicopathological features of KIT/PDGFRA wild-type gastrointestinal stromal tumors. | Molecular and clinicopathological features of KIT/PDGFRA wild-type gastrointestinal stromal tumors. Nishida T, Naito Y, Takahashi T, Saito T, Hisamori S, Manaka D, Ogawa K, Hirota S, Ichikawa H., Free PMC Article | 03/13/2024 |
CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate. | CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate. Bal G, Schneikert J, Li Z, Franke K, Tripathi SR, Zuberbier T, Babina M., Free PMC Article | 01/16/2024 |
Novel somatic Missense Mutations in Exon 11 of the KIT Gene are Detected in Melanoma. | Novel somatic Missense Mutations in Exon 11 of the KIT Gene are Detected in Melanoma. Palkina N, Tyumentseva A, Ruksha T., Free PMC Article | 01/8/2024 |
KIT genetic alterations in breast cancer. | KIT genetic alterations in breast cancer. Vahdatinia M, Derakhshan F, Da Cruz Paula A, Dopeso H, Marra A, Gazzo AM, Brown D, Selenica P, Ross DS, Razavi P, Zhang H, Weigelt B, Wen HY, Brogi E, Reis-Filho JS, Pareja F., | 12/18/2023 |
KIT Mutations and Other Genetic Defects in Mastocytosis: Implications for Disease Pathology and Targeted Therapies. | KIT Mutations and Other Genetic Defects in Mastocytosis: Implications for Disease Pathology and Targeted Therapies. Chantran Y, Valent P, Arock M. | 10/24/2023 |
Golgi retention and oncogenic KIT signaling via PLCgamma2-PKD2-PI4KIIIbeta activation in gastrointestinal stromal tumor cells. | Golgi retention and oncogenic KIT signaling via PLCγ2-PKD2-PI4KIIIβ activation in gastrointestinal stromal tumor cells. Obata Y, Kurokawa K, Tojima T, Natsume M, Shiina I, Takahashi T, Abe R, Nakano A, Nishida T. | 10/5/2023 |
PDGFRA, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance. | PDGFRA, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance. Carlotto BS, Trevisan P, Provenzi VO, Soares FP, Rosa RFM, Varella-Garcia M, Zen PRG., Free PMC Article | 09/25/2023 |
KIT D816V is dimerization-independent and activates downstream pathways frequently perturbed in mastocytosis. | KIT D816V is dimerization-independent and activates downstream pathways frequently perturbed in mastocytosis. Rajan V, Prykhozhij SV, Pandey A, Cohen AM, Rainey JK, Berman JN. | 09/1/2023 |
Bioinformatic analysis of KIT juxtamembrane domain mutations in Syrian GIST patients: jigsaw puzzle completed. | Bioinformatic analysis of KIT juxtamembrane domain mutations in Syrian GIST patients: jigsaw puzzle completed. Pharaon N, Habbal W, Monem F. | 08/19/2023 |
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling. | Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling. Cao X, Wu S, Wang X, Huang J, Zhang W, Liang C., Free PMC Article | 08/9/2023 |
KIT A502_Y503 duplication mutation serves as a potential and universal target for neoantigen peptide in Chinese GIST patients. | KIT A502_Y503 duplication mutation serves as a potential and universal target for neoantigen peptide in Chinese GIST patients. Liu F, Wang Q, Li Y, Li L, Shi J, Fan X, Pan Q, Li R. | 08/7/2023 |
c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation. | c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation. Xiong Y, Taleb M, Misawa K, Hou Z, Banerjee S, Amador-Molina A, Jones DR, Chintala NK, Adusumilli PS., Free PMC Article | 08/3/2023 |
Mechanism of immune escape mediated by receptor tyrosine kinase KIT in thyroid cancer. | Mechanism of immune escape mediated by receptor tyrosine kinase KIT in thyroid cancer. Luo Z, Xu J, Xu D, Xu J, Zhou R, Deng K, Chen Z, Zou F, Yao L, Hu Y., Free PMC Article | 08/1/2023 |
Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557-558 Deletion Mutations. | Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557-558 Deletion Mutations. Ohshima K, Nagashima T, Fujiya K, Hatakeyama K, Watanabe Y, Morimoto K, Kamada F, Shimoda Y, Ohnami S, Naruoka A, Serizawa M, Ohnami S, Kenmotsu H, Shiomi A, Tsubosa Y, Bando E, Sugiura T, Sugino T, Terashima M, Uesaka K, Urakami K, Akiyama Y, Yamaguchi K., Free PMC Article | 07/3/2023 |
Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide. | Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide. Jang A, Lanka SM, Huang M, Casado CV, Caputo SA, Sweeney PL, Gupta K, Pocha O, Habibian N, Hawkins ME, Lieberman AD, Schwartz J, Jaeger EB, Miller PJ, Layton JL, Barata PC, Lewis BE, Ledet EM, Sartor O. | 06/29/2023 |
Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells. | Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells. Franke K, Bal G, Li Z, Zuberbier T, Babina M., Free PMC Article | 05/19/2023 |
Low c-Kit expression identifies primitive, therapy-resistant CML stem cells. | Low c-Kit expression identifies primitive, therapy-resistant CML stem cells. Shah M, Kumar H, Qiu S, Li H, Harris M, He J, Abraham A, Crossman DK, Paterson A, Welner RS, Bhatia R., Free PMC Article | 01/14/2023 |
Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders. | Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders. Kanezaki R, Toki T, Terui K, Sato T, Kobayashi A, Kudo K, Kamio T, Sasaki S, Kawaguchi K, Watanabe K, Ito E., Free PMC Article | 12/17/2022 |
Identification and in silico analysis of noval alteration Arg420Gly in KIT proto oncogene among acute myeloid leukemia patients. | Identification and in silico analysis of noval alteration Arg420Gly in KIT proto oncogene among acute myeloid leukemia patients. Akram AM, Hassan M, Chaudhary A, Hayat S, Ali Q, Hussain T, Zafar A, Javed MA., Free PMC Article | 11/19/2022 |
Gastrointestinal stromal tumors caused by novel germline variants in SDHB and KIT: a report of two cases and literature review. | Gastrointestinal stromal tumors caused by novel germline variants in SDHB and KIT: a report of two cases and literature review. Rasmussen S, Stueck A, Colwell B, Gaston D, Carter M. | 10/29/2022 |
Effect of miR-129-3p on autophagy of interstitial cells of Cajal in slow transit constipation through SCF C-kit signaling pathway. | Effect of miR-129-3p on autophagy of interstitial cells of Cajal in slow transit constipation through SCF C-kit signaling pathway. Wang H, Ren B, Pan J, Fu S, Liu C, Sun D. | 10/15/2022 |
Role and significance of c-KIT receptor tyrosine kinase in cancer: A review. | Role and significance of c-KIT receptor tyrosine kinase in cancer: A review. Sheikh E, Tran T, Vranic S, Levy A, Bonfil RD., Free PMC Article | 10/15/2022 |