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    JUNB JunB proto-oncogene, AP-1 transcription factor subunit [ Homo sapiens (human) ]

    Gene ID: 3726, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity.

    Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity.
    Lind J, Aksoy O, Prchal-Murphy M, Fan F, Fulciniti M, Stoiber D, Bakiri L, Wagner EF, Zwickl-Traxler E, Sattler M, Kollmann K, Vallet S, Podar K., Free PMC Article

    09/27/2024
    Comprehensive Analysis of CXCR4, JUNB, and PD-L1 Expression in Circulating Tumor Cells (CTCs) from Prostate Cancer Patients.

    Comprehensive Analysis of CXCR4, JUNB, and PD-L1 Expression in Circulating Tumor Cells (CTCs) from Prostate Cancer Patients.
    Roumeliotou A, Strati A, Chamchougia F, Xagara A, Tserpeli V, Smilkou S, Lagopodi E, Christopoulou A, Kontopodis E, Drositis I, Androulakis N, Georgoulias V, Koinis F, Kotsakis A, Lianidou E, Kallergi G., Free PMC Article

    06/27/2024
    JunB condensation attenuates vascular endothelial damage under hyperglycemic condition.

    JunB condensation attenuates vascular endothelial damage under hyperglycemic condition.
    Ren X, Cui Z, Zhang Q, Su Z, Xu W, Wu J, Jiang H., Free PMC Article

    06/12/2024
    Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause.

    Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause.
    Pei W, Cao X, Zhang P, Fu L, Zhou P, Liu Y, Fan Y, Xu F, Cao C, Yu Y., Free PMC Article

    03/8/2024
    The activator protein-1 complex governs a vascular degenerative transcriptional programme in smooth muscle cells to trigger aortic dissection and rupture.

    The activator protein-1 complex governs a vascular degenerative transcriptional programme in smooth muscle cells to trigger aortic dissection and rupture.
    Luo Y, Luo J, An P, Zhao Y, Zhao W, Fang Z, Xia Y, Zhu L, Xu T, Zhang X, Zhou S, Yang M, Li J, Zhu J, Liu Y, Li H, Gong M, Liu Y, Han J, Guo H, Zhang H, Jiang W, Ren F.

    01/30/2024
    AP-1 signaling modulates cardiac fibroblast stress responses.

    AP-1 signaling modulates cardiac fibroblast stress responses.
    Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ., Free PMC Article

    12/21/2023
    JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis.

    JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis.
    Li S, Wei Y, Sun X, Liu M, Zhu M, Yuan Y, Zhang J, Dong Y, Hu K, Ma S, Zhang X, Xu B, Jiang H, Gan L, Liu T., Free PMC Article

    11/22/2023
    Transcription Factor JunB Suppresses Hepatitis C Virus Replication.

    Transcription Factor JunB Suppresses Hepatitis C Virus Replication.
    Ariffianto A, Deng L, Harada S, Liang Y, Matsui C, Abe T, Shoji I., Free PMC Article

    09/27/2023
    Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium.

    Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium.
    Ramos RB, Martino N, Chuy D, Lu S, Zuo MXG, Balasubramanian U, Di John Portela I, Vincent PA, Adam AP., Free PMC Article

    09/26/2023
    Glial AP1 is activated with aging and accelerated by traumatic brain injury.

    Glial AP1 is activated with aging and accelerated by traumatic brain injury.
    Byrns CN, Saikumar J, Bonini NM., Free PMC Article

    07/25/2023
    ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.

    ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.
    Liu Q, Yang T, Zhang Y, Hu ZD, Liu YM, Luo YL, Liu SX, Zhang H, Zhong Q., Free PMC Article

    07/25/2023
    m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-beta-induced epithelial-mesenchymal transition of lung cancer cells.

    m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells.
    Suphakhong K, Terashima M, Wanna-Udom S, Takatsuka R, Ishimura A, Takino T, Suzuki T., Free PMC Article

    12/17/2022
    AP-1 Subunit JUNB Promotes Invasive Phenotypes in Endometriosis.

    AP-1 Subunit JUNB Promotes Invasive Phenotypes in Endometriosis.
    Wilson MR, Reske JJ, Chandler RL., Free PMC Article

    11/19/2022
    FGF7/FGFR2-JunB signalling counteracts the effect of progesterone in luminal breast cancer.

    FGF7/FGFR2-JunB signalling counteracts the effect of progesterone in luminal breast cancer.
    Mieczkowski K, Kitowska K, Braun M, Galikowska-Bogut B, Gorska-Arcisz M, Piasecka D, Stawiski K, Zaczek AJ, Nejc D, Kordek R, Romanska HM, Sadej R., Free PMC Article

    08/13/2022
    JunB is a key regulator of multiple myeloma bone marrow angiogenesis.

    JunB is a key regulator of multiple myeloma bone marrow angiogenesis.
    Fan F, Malvestiti S, Vallet S, Lind J, Garcia-Manteiga JM, Morelli E, Jiang Q, Seckinger A, Hose D, Goldschmidt H, Stadlbauer A, Sun C, Mei H, Pecherstorfer M, Bakiri L, Wagner EF, Tonon G, Sattler M, Hu Y, Tassone P, Jaeger D, Podar K., Free PMC Article

    01/29/2022
    Skp2 promotes APL progression through the stabilization of oncoprotein PML-RARalpha and the inhibition of JunB expression.

    Skp2 promotes APL progression through the stabilization of oncoprotein PML-RARα and the inhibition of JunB expression.
    Dan W, Zhong L, Yu L, Xiong L, Li J, Ye J, Luo X, Liu C, Chu X, Liu B.

    01/15/2022
    Circular RNA PUM1 (CircPUM1) attenuates trophoblast cell dysfunction and inflammation in recurrent spontaneous abortion via the MicroRNA-30a-5p (miR-30a-5p)/JUNB axis.

    Circular RNA PUM1 (CircPUM1) attenuates trophoblast cell dysfunction and inflammation in recurrent spontaneous abortion via the MicroRNA-30a-5p (miR-30a-5p)/JUNB axis.
    Zhu L, Shi L, Ye W, Li S, Liu X, Zhu Z., Free PMC Article

    01/1/2022
    JUNB-FBXO21-ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy.

    JUNB-FBXO21-ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy.
    Lin Z, Miao J, Zhang T, He M, Wang Z, Feng X, Bai L., Free PMC Article

    09/11/2021
    JunB can enhance the transcription of IL-8 in oral squamous cell carcinoma.

    JunB can enhance the transcription of IL-8 in oral squamous cell carcinoma.
    Tsunoda M, Fukasawa M, Nishihara A, Takada L, Asano M.

    08/28/2021
    miR3133 inhibits proliferation and angiogenesis by targeting the JUNB/VEGF pathway in human umbilical vein endothelial cells.

    miR‑3133 inhibits proliferation and angiogenesis by targeting the JUNB/VEGF pathway in human umbilical vein endothelial cells.
    Xu M, Cao L, Zhang X, Zhuang Y, Zhang Y, Wang Q, Chen Y, Xu L, Sun G.

    07/10/2021
    miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma.

    miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma.
    Garbin A, Lovisa F, Holmes AB, Damanti CC, Gallingani I, Carraro E, Accordi B, Veltri G, Pizzi M, d'Amore ESG, Pillon M, Biffi A, Basso K, Mussolin L., Free PMC Article

    07/10/2021
    Activating transcription factor 3 inhibits endometrial carcinoma aggressiveness via JunB suppression.

    Activating transcription factor 3 inhibits endometrial carcinoma aggressiveness via JunB suppression.
    Wang F, Li J, Wang H, Zhang F, Gao J., Free PMC Article

    06/12/2021
    Tumor-associated macrophages promote prostate cancer progression via exosome-mediated miR-95 transfer.

    Tumor-associated macrophages promote prostate cancer progression via exosome-mediated miR-95 transfer.
    Guan H, Peng R, Fang F, Mao L, Chen Z, Yang S, Dai C, Wu H, Wang C, Feng N, Xu B, Chen M.

    04/13/2021
    PKCtheta-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization.

    PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization.
    Kumar R, Mani AM, Singh NK, Rao GN., Free PMC Article

    03/20/2021
    ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.

    ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription.
    Yao F, Wang X, Cui ZK, Lan H, Ai X, Song Q, Chen Z, Yang J, Wu B, Bai X.

    09/26/2020
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