| Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature. | Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature.
van der Laan L, Rooney K, Haghshenas S, Silva A, McConkey H, Relator R, Levy MA, Valenzuela I, Trujillano L, Lasa-Aranzasti A, Campos B, Castells N, Verberne EA, Maas S, Alders M, Mannens MMAM, van Haelst MM, Sadikovic B, Henneman P., Free PMC Article | 09/30/2023 |
| JARID2 and EZH2, the eminent epigenetic drivers in human cancer. | JARID2 and EZH2, the eminent epigenetic drivers in human cancer.
Sreeshma B, Devi A. | 07/25/2023 |
| Integrated bioinformatics and experimental validation reveal the role of JARID2 in ovarian cancer. | Integrated bioinformatics and experimental validation reveal the role of JARID2 in ovarian cancer.
Huang D, Wang R, Tian L, Wang H. | 07/13/2023 |
| JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis. | JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis.
Gu Y, Ding Z, Zhou Q, Li J, Qian W. | 02/28/2023 |
| The LINC00852/miR-29a-3p/JARID2 axis regulates the proliferation and invasion of prostate cancer cell. | The LINC00852/miR-29a-3p/JARID2 axis regulates the proliferation and invasion of prostate cancer cell.
Zhang H, Du Y, Xin P, Man X., Free PMC Article | 12/17/2022 |
| microRNA-206 Suppresses Cholangiocarcinoma Cell Growth and Invasion by Targeting Jumonji AT-Rich Interactive Domain 2. | microRNA-206 Suppresses Cholangiocarcinoma Cell Growth and Invasion by Targeting Jumonji AT-Rich Interactive Domain 2.
Xie C, Huang Z, Huang Z, Zhang X, Lou S. | 07/2/2022 |
| LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer. | LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.
Wu H, Ding X, Hu X, Zhao Q, Chen Q, Sun T, Li Y, Guo H, Li M, Gao Z, Yao W, Zhao L, Li K, Wei M. | 04/23/2022 |
| LINC00649 Facilitates the Cellular Process of Bladder Cancer Cells via Signaling Axis miR-16-5p/JARID2. | LINC00649 Facilitates the Cellular Process of Bladder Cancer Cells via Signaling Axis miR-16-5p/JARID2.
Liu Y, Huang X, Guo L, Luo N. | 03/19/2022 |
| Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy. | Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy.
Fang Y, Tao Y, Zhou H, Lai H. | 03/5/2022 |
| An RNAi Screening of Clinically Relevant Transcription Factors Regulating Human Adipogenesis and Adipocyte Metabolism. | An RNAi Screening of Clinically Relevant Transcription Factors Regulating Human Adipogenesis and Adipocyte Metabolism.
Björk C, Subramanian N, Liu J, Acosta JR, Tavira B, Eriksson AB, Arner P, Laurencikiene J., Free PMC Article | 10/9/2021 |
| JARID2 promotes stemness and cisplatin resistance in non-small cell lung cancer via upregulation of Notch1. | JARID2 promotes stemness and cisplatin resistance in non-small cell lung cancer via upregulation of Notch1.
Wang Q, Wu J, Wei H, Huang H, Huang Y, Fang H, Gong X, Sun J, Wu Y, Lei C, Yu J, Hu D. | 10/2/2021 |
| JARID2 haploinsufficiency is associated with a clinically distinct neurodevelopmental syndrome. | JARID2 haploinsufficiency is associated with a clinically distinct neurodevelopmental syndrome.
Verberne EA, Goh S, England J, van Ginkel M, Rafael-Croes L, Maas S, Polstra A, Zarate YA, Bosanko KA, Pechter KB, Bedoukian E, Izumi K, Chaudhry A, Robin NH, Boothe M, Lippa NC, Aggarwal V, De Vivo DC, Lehman A, Study C, Stockler S, Bruel AL, Isidor B, Lemons J, Rodriguez-Buritica DF, Richmond CM, Stark Z, Agrawal PB, Kooy RF, Meuwissen MEC, Koolen DA, Pfundt R, Lieden A, Anderlid BM, Glatz D, Mannens MMAM, Bakshi M, Mallette FA, van Haelst MM, Campeau PM. | 07/10/2021 |
| JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. | JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Kasinath V, Beck C, Sauer P, Poepsel S, Kosmatka J, Faini M, Toso D, Aebersold R, Nogales E., Free PMC Article | 02/27/2021 |
| show that DeltaN-JARID2 is a cleaved product of full-length JARID2 spanning the C-terminal conserved jumonji domains. JARID2 knockout in keratinocytes results in up-regulation of cell cycle genes and repression of many epidermal differentiation genes | A novel form of JARID2 is required for differentiation in lineage-committed cells.
Al-Raawi D, Jones R, Wijesinghe S, Halsall J, Petric M, Roberts S, Hotchin NA, Kanhere A., Free PMC Article | 01/11/2020 |
| In this study, genetic mouse models and patient-derived xenografts demonstrated that JARID2 acts as a tumor suppressor in chronic myeloid disorders. | JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells.
Celik H, Koh WK, Kramer AC, Ostrander EL, Mallaney C, Fisher DAC, Xiang J, Wilson WC, Martens A, Kothari A, Fishberger G, Tycksen E, Karpova D, Duncavage EJ, Lee Y, Oh ST, Challen GA., Free PMC Article | 08/3/2019 |
| rs2237126 in JARID2 is not significantly associated with childhood autism spectrum disorder or the severity of the disease in a Chinese Han population. | A study of single nucleotide polymorphisms in CD157, AIM2 and JARID2 genes in Han Chinese children with autism spectrum disorder.
Mo W, Liu J, Zhang Z, Yu H, Yang A, Qu F, Hu P, Liu Z, Hu F. | 08/25/2018 |
| bservations suggested that knockdown of JARID2 inhibited proliferation, migration and invasion in vitro through the inactivation of the PI3K/Akt signaling pathway. Therefore, JARID2 may represent a potential therapeutic target for the treatment of ovarian cancer. | Knockdown of JARID2 inhibits the proliferation and invasion of ovarian cancer through the PI3K/Akt signaling pathway.
Cao J, Li H, Liu G, Han S, Xu P. | 04/28/2018 |
| The knockdown of JARID2 inhibited the viability and invasion of trophoblast cells in preeclampsia by suppressing the PI3K/Akt signaling pathway. | Knockdown of JARID2 inhibits the viability and migration of placenta trophoblast cells in preeclampsia.
Jiang Y, Chen Y, Chen Y. | 04/28/2018 |
| Authors found that knockdown of Jarid2 was able to inhibit the invasive ability and sphere-forming capacity in bladder cancer cells. | Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer.
Zhu XX, Yan YW, Ai CZ, Jiang S, Xu SS, Niu M, Wang XZ, Zhong GS, Lu XF, Xue Y, Tian S, Li G, Tang S, Jiang YZ., Free PMC Article | 03/24/2018 |
| Our results suggest that JARID2 rs2237138 shows a protective effect against NSCL +/- P (non-syndromic oral clefts)in the Brazilian population. | Brazilian multicenter study of association between polymorphisms in CRISPLD2 and JARID2 and non-syndromic oral clefts.
Messetti AC, Machado RA, de Oliveira CE, Martelli-Júnior H, de Almeida Reis SR, Moreira HS, Persuhn DC, Wu T, Coletta RD. | 02/17/2018 |
| JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition through PTEN/AKT signaling | JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition through PTEN/AKT signaling.
Lei X, Xu JF, Chang RM, Fang F, Zuo CH, Yang LY., Free PMC Article | 01/20/2018 |
| JARID2 plays an important role in glioma development. | Reduced Expression of Jumonji AT-Rich Interactive Domain 2 (JARID2) in Glioma Inhibits Tumor Growth In Vitro and In Vivo.
Li Z, Xu C, Gao M, Ding B, Wei X, Ji N., Free PMC Article | 03/25/2017 |
| Data further strengthen the conclusion that JARID2 polymorphisms are associated with NSOC susceptibility. | Association of JARID2 polymorphisms with non-syndromic orofacial clefts in northern Chinese Han population.
Hao Y, Mi N, Jiao X, Zheng X, Song T, Zhuang D, Tian S, Feng D. | 07/30/2016 |
| JARID2 inhibits leukemia cell proliferation by regulating CCND1 expression | JARID2 inhibits leukemia cell proliferation by regulating CCND1 expression.
Su CL, Deng TR, Shang Z, Xiao Y. | 02/27/2016 |
| TGF-ss-dependent expression changes of EMT-related genes were inhibited by JARID2 knockdown and enhanced by JARID2 overexpression. | JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines.
Tange S, Oktyabri D, Terashima M, Ishimura A, Suzuki T., Free PMC Article | 09/5/2015 |