| PAX5/ITGAX Contributed to the Progression of Atherosclerosis by Regulation of B Differentiation via TNF-alpha Signaling Pathway. | PAX5/ITGAX Contributed to the Progression of Atherosclerosis by Regulation of B Differentiation via TNF-α Signaling Pathway.
Wang X, Guan Z, Tang W, Wang X, Xu C, Shan E, Wang W, Gao Y. | 02/18/2023 |
| SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells.
Ni L, Li P, Li M, Huang S, Dang N. | 01/14/2023 |
| Decreased CD11c-positive dendritic cells in the tumor microenvironment predict double-hit/triple-hit genotype and survival in diffuse large B-cell lymphoma. | Decreased CD11c-positive dendritic cells in the tumor microenvironment predict double-hit/triple-hit genotype and survival in diffuse large B-cell lymphoma.
Yuan CT, Chuang SS, Cheng PY, Chang K, Wang H, Tsai JH, Liau JY, Chou WC., Free PMC Article | 08/13/2022 |
| Identification of ITGAX and CCR1 as potential biomarkers of atherosclerosis via Gene Set Enrichment Analysis. | Identification of ITGAX and CCR1 as potential biomarkers of atherosclerosis via Gene Set Enrichment Analysis.
Yan S, Meng L, Guo X, Chen Z, Zhang Y, Li Y., Free PMC Article | 04/9/2022 |
| BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. | BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1.
Nagy-Baló Z, Kiss R, Demeter J, Bödör C, Bajtay Z, Erdei A., Free PMC Article | 11/13/2021 |
| Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study. | Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study.
Lokki AI, Teirilä L, Triebwasser M, Daly E, Bhattacharjee A, Uotila L, Llort Asens M, Kurki MI, Perola M, Auro K, Salmon JE, Daly M, Atkinson JP, Laivuori H, Fagerholm S, Meri S, Finnpec., Free PMC Article | 09/18/2021 |
| Moieties of Complement iC3b Recognized by the I-domain of Integrin alphaXbeta2. | Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2.
Choi J, Buyannemekh D, Nham SU., Free PMC Article | 07/31/2021 |
| Activated Human Memory B Lymphocytes Use CR4 (CD11c/CD18) for Adhesion, Migration, and Proliferation. | Activated Human Memory B Lymphocytes Use CR4 (CD11c/CD18) for Adhesion, Migration, and Proliferation.
Nagy-Baló Z, Kiss R, Menge A, Bödör C, Bajtay Z, Erdei A., Free PMC Article | 05/8/2021 |
| High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer. | High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer.
Corvigno S, Mezheyeuski A, De La Fuente LM, Westbom-Fremer S, Carlson JW, Fernebro J, Åvall-Lundqvist E, Kannisto P, Hedenfalk I, Malander S, Rolny C, Dahlstrand H, Östman A. | 04/24/2021 |
| Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients. | Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients.
Chang CK, Chen PK, Lan JL, Chang SH, Hsieh TY, Liao PJ, Chen CH, Chen DY., Free PMC Article | 04/17/2021 |
| An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. | An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes.
Hernandez AA, Foster GA, Soderberg SR, Fernandez A, Reynolds MB, Orser MK, Bailey KA, Rogers JH, Singh GD, Wu H, Passerini AG, Simon SI., Free PMC Article | 04/17/2021 |
| ITGAX stimulates angiogenesis of ovarian cancer through the PI3K/Akt signaling-mediated VEGF-A/VEGFR2 expression in endothelial cells, suggesting that ITGAX may be a novel target in the treatment of cancers, especially those with high angiogenic capacity. | Integrin alpha x stimulates cancer angiogenesis through PI3K/Akt signaling-mediated VEGFR2/VEGF-A overexpression in blood vessel endothelial cells.
Wang J, Yang L, Liang F, Chen Y, Yang G. | 02/29/2020 |
| results suggested that ITGAX and ITGAM gene polymorphisms were associated with IgA nephropathy (IgAN) in a Chinese Han population, and the rs11150619-T allele showed a potential protective role for IgAN. | Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy.
Shi D, Zhong Z, Xu R, Li B, Li J, Habib U, Peng Y, Mao H, Li Z, Huang F, Yu X, Li M. | 12/28/2019 |
| We demonstrated a strong correlation of CD11c expression, which represents dendritic cells (DCs) , with Tumor-infiltrating lymphocytes (TILs) and TLSs in triple-negative breast cancer (TNBC). Further investigation is warranted to identify therapeutic modalities that facilitate recruitment and activation of DCs. | CD11c-Positive Dendritic Cells in Triple-negative Breast Cancer.
Lee H, Lee HJ, Song IH, Bang WS, Heo SH, Gong G, Park IA., Free PMC Article | 01/26/2019 |
| This study provides evidence that CD11c is involved in the susceptibility to Behcet's disease in a Chinese Han population. | Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population.
Zheng M, Zhang L, Yu H, Hu J, Cao Q, Huang G, Huang Y, Yuan G, Kijlstra A, Yang P., Free PMC Article | 09/8/2018 |
| The main mechanism of Integrin alphaXbeta2 I-domain binding to RAGE is a charge interaction, in which the acidic moieties of Integrin alphaXbeta2 I-domains, including E244, and D249, recognize the basic residues on the RAGE V-domain encompassing K39, K43, K44, R104, and K107. | Characterization of αX I-Domain Binding to Receptors for Advanced Glycation End Products (RAGE).
Buyannemekh D, Nham SU., Free PMC Article | 03/24/2018 |
| Studies indicate that CD11c+ T-bet+ memory B cells exhibit a distinct transcriptome. | CD11c+ T-bet+ memory B cells: Immune maintenance during chronic infection and inflammation?
Winslow GM, Papillion AM, Kenderes KJ, Levack RC., Free PMC Article | 12/30/2017 |
| Studies indicate enriched expression of TBX21 (T-bet), which is important for B cell survival and response to antigen, was observed in CD11c+ B cells. | Role of CD11c(+) T-bet(+) B cells in human health and disease.
Karnell JL, Kumar V, Wang J, Wang S, Voynova E, Ettinger R. | 12/30/2017 |
| CD11c, expressed not only in Hairy cell leukemia but also in dendritic cells, macrophages and monocytes is a differentiation marker for inflammation. Prolonged inflammation in the microenvironment of CLL cells may cause a susceptibility to autoimmune disorders and secondary tumors in CLL, in this way, an increase in mortality. | CD11c expression in chronic lymphocytic leukemia revisited, related with complications and survival.
Umit EG, Baysal M, Durmus Y, Demir AM. | 10/21/2017 |
| We can achieve possible clinical significance of lymphoma tumor microenvironments through CD11c and FOXP3 immunohistochemistry stains in extranodal diffuse large B-cell lymphoma patients receiving R-CHOP therapy. | Clinicopathologic significance of tumor microenvironment CD11c, and FOXP3 expression in diffuse large B-cell lymphoma patients receiving rituximab, cyclophosphamide, anthracycline, vincristine, and prednisone (R-CHOP) combination chemotherapy.
Lee S, Kim DH, Oh SY, Kim SY, Koh MS, Lee JH, Lee S, Kim SH, Kwak JY, Pak MG, Ju MH, Kim HJ, Jeong JS., Free PMC Article | 08/26/2017 |
| Circulating CD11c+ T cells were associated with the expression of multiple adhesion molecules in women, suggesting that these cells have high tissue homing potential. These data suggest that CD11c expression distinguishes a population of circulating T cells during bacterial infection with innate capacity and mucosal homing potential. | Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential.
Qualai J, Li LX, Cantero J, Tarrats A, Fernández MA, Sumoy L, Rodolosse A, McSorley SJ, Genescà M., Free PMC Article | 03/18/2017 |
| CD8+ T cells of Behcet's disease patients exhibited increased CD11c expression levels, which may contribute to disease pathogenesis. | CD11c is upregulated in CD8+ T cells of patients with Behçet's disease.
Park YJ, Park MJ, Park S, Lee ES. | 02/18/2017 |
| High expression of CD11c decreased the risk of death and relapse, and may be regarded as an alternative indicator of favorable prognosis in patients with gastric cancer. | High expression of CD11c indicates favorable prognosis in patients with gastric cancer.
Wang Y, Xu B, Hu WW, Chen LJ, Wu CP, Lu BF, Shen YP, Jiang JT., Free PMC Article | 10/8/2016 |
| the CD11c molecule possesses four different cellular patterns in the periprosthetic tissues. | Expression of CD11c in periprosthetic tissues from failed total hip arthroplasties.
Chamaon K, Barber H, Awiszus F, Feuerstein B, Lohmann CH. | 10/1/2016 |
| Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H), factor H-receptors CD11b/CD18 and CD11c/CD18. | Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18).
Svoboda E, Schneider AE, Sándor N, Lermann U, Staib P, Kremlitzka M, Bajtay Z, Barz D, Erdei A, Józsi M. | 09/17/2016 |