| Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis. | Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis.
Moye AL, Dost AF, Ietswaart R, Sengupta S, Ya V, Aluya C, Fahey CG, Louie SM, Paschini M, Kim CF., Free PMC Article | 08/13/2024 |
| Integrin alpha3 promotes TH17 cell polarization and extravasation during autoimmune neuroinflammation. | Integrin α3 promotes T(H)17 cell polarization and extravasation during autoimmune neuroinflammation.
Park E, Barclay WE, Barrera A, Liao TC, Salzler HR, Reddy TE, Shinohara ML, Ciofani M., Free PMC Article | 11/2/2023 |
| Integrin alpha3 Mediates Stemness and Invasion of Glioblastoma by Regulating POU3F2. | Integrin α3 Mediates Stemness and Invasion of Glioblastoma by Regulating POU3F2.
Yao J, Wang L. | 06/2/2023 |
| YY1/ITGA3 pathway may affect trophoblastic cells migration and invasion ability. | YY1/ITGA3 pathway may affect trophoblastic cells migration and invasion ability.
Wang Y, Yang D, Zhu R, Dai F, Yuan M, Zhang L, Zheng Y, Liu S, Yang X, Cheng Y. | 10/8/2022 |
| miRNA-144-5p/ITGA3 Suppressed the Tumor-Promoting Behaviors of Thyroid Cancer Cells by Downregulating ITGA3. | miRNA-144-5p/ITGA3 Suppressed the Tumor-Promoting Behaviors of Thyroid Cancer Cells by Downregulating ITGA3.
Zhang J, Zhong Y, Sang Y, Ren G., Free PMC Article | 02/5/2022 |
| Homozygous ITGA3 Missense Mutation in Adults in a Family with Syndromic Epidermolysis Bullosa (ILNEB) without Pulmonary Involvement. | Homozygous ITGA3 Missense Mutation in Adults in a Family with Syndromic Epidermolysis Bullosa (ILNEB) without Pulmonary Involvement.
Kinyó Á, Kovács AL, Degrell P, Kálmán E, Nagy N, Kárpáti S, Gyulai R, Saeidian AH, Youssefian L, Vahidnezhad H, Uitto J. | 02/5/2022 |
| CD9 and ITGA3 are regulated during HIV-1 infection in macrophages to support viral replication. | CD9 and ITGA3 are regulated during HIV-1 infection in macrophages to support viral replication.
Kruize Z, Cobos Jiménez V, Martinez FO, Di Vincenzo R, van Dort KA, van Nuenen AC, Booiman T, Kootstra NA. | 01/8/2022 |
| Detection of bladder cancer with aberrantly fucosylated ITGA3. | Detection of bladder cancer with aberrantly fucosylated ITGA3.
Islam MK, Syed P, Dhondt B, Gidwani K, Pettersson K, Lamminmäki U, Leivo J. | 12/11/2021 |
| Key Role of CD151-integrin Complex in Lung Cancer Metastasis and Mechanisms Involved. | Key Role of CD151-integrin Complex in Lung Cancer Metastasis and Mechanisms Involved.
Peng D, Li PC, Liu T, Zeng HS, Fei YJ, Liu ZX, Zuo HJ. | 09/25/2021 |
| Skin fragility, renal malformation and interstitial lung disease due to compound heterozygous ITGA3 mutations. | Skin fragility, renal malformation and interstitial lung disease due to compound heterozygous ITGA3 mutations.
Sondermann W, Büscher R, Forster H, Stehling F, Fischer J, He Y, Has C. | 08/21/2021 |
| Expression and Prognostic Analyses of ITGA3, ITGA5, and ITGA6 in Head and Neck Squamous Cell Carcinoma. | Expression and Prognostic Analyses of ITGA3, ITGA5, and ITGA6 in Head and Neck Squamous Cell Carcinoma.
Feng C, Jin X, Han Y, Guo R, Zou J, Li Y, Wang Y., Free PMC Article | 07/10/2021 |
| MicroRNA199a5p suppresses cell proliferation, migration and invasion by targeting ITGA3 in colorectal cancer. | MicroRNA‑199a‑5p suppresses cell proliferation, migration and invasion by targeting ITGA3 in colorectal cancer.
Tian L, Chen M, He Q, Yan Q, Zhai C., Free PMC Article | 05/1/2021 |
| TMT-Based Quantitative Proteomic Analysis Identification of Integrin Alpha 3 and Integrin Alpha 5 as Novel Biomarkers in Pathogenesis of Acute Aortic Dissection. | TMT-Based Quantitative Proteomic Analysis Identification of Integrin Alpha 3 and Integrin Alpha 5 as Novel Biomarkers in Pathogenesis of Acute Aortic Dissection.
Xing L, Xue Y, Yang Y, Wu P, Wong CCL, Wang H, Song Z, Shi D, Tong C, Yao C, Gu G., Free PMC Article | 04/24/2021 |
| Paracoccidioides brasiliensis downmodulates alpha3 integrin levels in human lung epithelial cells in a TLR2-dependent manner. | Paracoccidioides brasiliensis downmodulates α3 integrin levels in human lung epithelial cells in a TLR2-dependent manner.
de Barros BCSC, Almeida BR, Suzuki E., Free PMC Article | 03/28/2021 |
| Anatomy of a viral entry platform differentially functionalized by integrins alpha3 and alpha6. | Anatomy of a viral entry platform differentially functionalized by integrins α3 and α6.
Finke J, Mikuličić S, Loster AL, Gawlitza A, Florin L, Lang T., Free PMC Article | 12/19/2020 |
| Alterations in the immunoreactivity of laminin, type IV collagen and alpha3beta1 integrin in diabetic rat ovarian follicles. | Alterations in the immunoreactivity of laminin, type IV collagen and α3β1 integrin in diabetic rat ovarian follicles.
Yildirim AB, Karabulut D, Ozturk E, Kaymak E, Yalcin B, Kuloglu N, Akkus E. | 09/19/2020 |
| Integrin-alpha3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells. | Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells.
Tomellini E, Fares I, Lehnertz B, Chagraoui J, Mayotte N, MacRae T, Bordeleau MÈ, Corneau S, Bisaillon R, Sauvageau G. | 08/29/2020 |
| MiR-524-5p targeting on FOXE1 and ITGA3 prevents thyroid cancer progression through different pathways including cell cycling and autophagy. | MicroRNA-524-5p suppresses the progression of papillary thyroid carcinoma cells via targeting on FOXE1 and ITGA3 in cell autophagy and cycling pathways.
Liu H, Chen X, Lin T, Chen X, Yan J, Jiang S., Free PMC Article | 05/30/2020 |
| The results strongly suggest that ITGA3 is a key molecule for cellular attachment and entry of non-enveloped hepatitis E virus. | Integrin α3 is involved in non-enveloped hepatitis E virus infection.
Shiota T, Li TC, Nishimura Y, Yoshizaki S, Sugiyama R, Shimojima M, Saijo M, Shimizu H, Suzuki R, Wakita T, Muramatsu M, Ishii K. | 04/11/2020 |
| Collectively, these findings suggest that integrin alpha3beta1 plays pivotal roles in regulating cell proliferation and migration that enhance the invasive type of p53-deficient NSCLC cells. | Knockdown of integrin α3β1 expression induces proliferation and migration of non-small cell lung cancer cells.
Yoon HJ, Cho YR, Joo JH, Seo DW. | 04/10/2020 |
| findings indicate that integrin alpha3 interacts with VASP and regulates its expression | ITGA3 interacts with VASP to regulate stemness and epithelial-mesenchymal transition of breast cancer cells.
Zhang H, Cui X, Cao A, Li X, Li L. | 03/7/2020 |
| Downregulation of alpha3beta1 in a HER2-driven mouse model and in HER2-overexpressing human mammary carcinoma cells promotes progression and invasiveness of tumors. The invasion-suppressive role of alpha3beta1 was not observed in triple-negative mammary carcinoma cells, illustrating the tumor type-specific and complex function of alpha3beta1 in breast cancer. | Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo.
Ramovs V, Secades P, Song JY, Thijssen B, Kreft M, Sonnenberg A., Free PMC Article | 01/11/2020 |
| both integrin alpha3beta1 and PI4KIIalpha co-localized to the trans-Golgi network, where they physically interacted with each other, and PI4KIIalpha specifically associated with integrin alpha3 but not alpha5 | A complex between phosphatidylinositol 4-kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells.
Isaji T, Im S, Kameyama A, Wang Y, Fukuda T, Gu J., Free PMC Article | 12/14/2019 |
| Up-regulation of integrin subunit alpha 3 (ITGA3) is observed in bladder cancer (BC) clinical samples and tumor cell lines. Silencing ITGA3 enhances apoptosis, inhibits tumor cell migration and invasion, and therefore decreases viability and proliferation of BC cells. | MicroRNA-124-3p suppresses cell migration and invasion by targeting ITGA3 signaling in bladder cancer.
Wang JR, Liu B, Zhou L, Huang YX. | 07/27/2019 |
| Elevated serum sFRP2 levels are associated with primary tumor size, tumor stage, and lymph node metastases. | Secreted Frizzled-Related Protein 2 Is Associated with Disease Progression and Poor Prognosis in Breast Cancer.
Huang C, Ye Z, Wan J, Liang J, Liu M, Xu X, Li L., Free PMC Article | 07/20/2019 |