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    AR androgen receptor [ Homo sapiens (human) ]

    Gene ID: 367, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Androgen Receptor Promotes Lung Cancer Metastasis by Modifying the miR23a-3p/EPHB2 Pathway.

    Androgen Receptor Promotes Lung Cancer Metastasis by Modifying the miR23a-3p/EPHB2 Pathway.
    Yang Y, Huang JW, Yu WW.

    10/25/2024
    Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells.

    Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells.
    Safi R, Wardell SE, Watkinson P, Qin X, Lee M, Park S, Krebs T, Dolan EL, Blattler A, Tsuji T, Nayak S, Khater M, Fontanillo C, Newlin MA, Kirkland ML, Xie Y, Long H, Fink EC, Fanning SW, Runyon S, Brown M, Xu S, Owzar K, Norris JD, McDonnell DP., Free PMC Article

    10/11/2024
    Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells.

    Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells.
    Launonen KM, Varis V, Aaltonen N, Niskanen EA, Varjosalo M, Paakinaho V, Palvimo JJ., Free PMC Article

    10/9/2024
    Pleckstrin-2 Mediates the Activation of AKT in Prostate Cancer and Is Repressed by Androgen Receptor.

    Pleckstrin-2 Mediates the Activation of AKT in Prostate Cancer and Is Repressed by Androgen Receptor.
    Han X, Zhang A, Wang P, Bi H, Ren K, Li E, Yang X, Aydemir I, Tao K, Lin J, Abdulkadir SA, Yang J, Ji P.,

    10/7/2024
    Androgen receptor deficiency-induced TUG1 in suppressing ferroptosis to promote benign prostatic hyperplasia through the miR-188-3p/GPX4 signal pathway.

    Androgen receptor deficiency-induced TUG1 in suppressing ferroptosis to promote benign prostatic hyperplasia through the miR-188-3p/GPX4 signal pathway.
    Zhan M, Xu H, Yu G, Chen Q, Yang R, Chen Y, Ge J, Wang Z, Yang R, Xu B., Free PMC Article

    10/2/2024
    Structural mechanism underlying variations in DNA binding by the androgen receptor.

    Structural mechanism underlying variations in DNA binding by the androgen receptor.
    Lee XY, Van Eynde W, Helsen C, Willems H, Peperstraete K, De Block S, Voet A, Claessens F.

    09/19/2024
    Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis.

    Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis.
    Lan KC, Cheng YH, Chang YC, Wei KT, Weng PL, Kang HY., Free PMC Article

    09/6/2024
    JMJD2A promotes the development of castration-resistant prostate cancer by activating androgen receptor enhancer and inhibiting the cGAS-STING pathway.

    JMJD2A promotes the development of castration-resistant prostate cancer by activating androgen receptor enhancer and inhibiting the cGAS-STING pathway.
    Cai X, Yu X, Tang T, Xu Y, Wu T.

    08/27/2024
    The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells.

    The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells.
    Huo C, Kuo YY, Lin CY, Shiah SG, Li CY, Huang SP, Chen JK, Wang WC, Kung HJ, Chuu CP., Free PMC Article

    08/20/2024
    AR loss in prostate cancer stroma mediated by NF-kappaB and p38-MAPK signaling disrupts stromal morphogen production.

    AR loss in prostate cancer stroma mediated by NF-κB and p38-MAPK signaling disrupts stromal morphogen production.
    Tahsin S, Sane NS, Cernyar B, Jiang L, Zohar Y, Lee BR, Miranti CK.

    07/23/2024
    Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs.

    Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs.
    Han D, Labaf M, Zhao Y, Owiredu J, Zhang S, Patel K, Venkataramani K, Steinfeld JS, Han W, Li M, Liu M, Wang Z, Besschetnova A, Patalano S, Mulhearn MJ, Macoska JA, Yuan X, Balk SP, Nelson PS, Plymate SR, Gao S, Siegfried KR, Liu R, Stangis MM, Foxa G, Czernik PJ, Williams BO, Zarringhalam K, Li X, Cai C., Free PMC Article

    07/8/2024
    Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients.

    Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients.
    James DW, Quintela M, Lucini L, Alkafri NK, Healey GD, Younas K, Bunkheila A, Margarit L, Francis LW, Gonzalez D, Conlan RS., Free PMC Article

    07/8/2024
    The RNA secondary structure of androgen receptor-FL and V7 transcripts reveals novel regulatory regions.

    The RNA secondary structure of androgen receptor-FL and V7 transcripts reveals novel regulatory regions.
    Rouse WB, Tompkins VS, O'Leary CA, Moss WN., Free PMC Article

    06/24/2024
    Androgen Receptor Splice Variant 7 in Asian Patients With Metastatic Castration-Resistant Prostate Cancer.

    Androgen Receptor Splice Variant 7 in Asian Patients With Metastatic Castration-Resistant Prostate Cancer.
    Ang D, Chan J, Ong WS, Tan HS, Ng QS, Yuen J, Chen K, Tay KJ, Wong SW, Saad M, Nagata M, Horie S, Chansriwong P, Ng CF, Wong A, Chua MLK, Toh CK, Tan MH, Lim T, Bhagat AAS, Kanesvaran R.

    06/24/2024
    AR-V7 expression facilitates accelerated G2/M phase transition in castration-resistant prostate cancer.

    AR-V7 expression facilitates accelerated G2/M phase transition in castration-resistant prostate cancer.
    Saini T, Gupta P, Raut R, Nayak V, Bharathnaveen P, Mishra P, Misra A.

    05/30/2024
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.

    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
    Hosseinzadeh L, Kikhtyak Z, Laven-Law G, Pederson SM, Puiu CG, D'Santos CS, Lim E, Carroll JS, Tilley WD, Dwyer AR, Hickey TE., Free PMC Article

    03/11/2024
    Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.

    Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.
    Ma T, Jin L, Bai S, Liu Z, Wang S, Shen B, Cho Y, Cao S, Sun MJS, Fazli L, Zhang D, Wedderburn C, Zhang DY, Mugon G, Ungerleider N, Baddoo M, Zhang K, Schiavone LH, Burkhardt BR, Fan J, You Z, Flemington EK, Dong X, Dong Y., Free PMC Article

    03/8/2024
    Modelling the distinct roles of epithelial and stromal androgen receptor in the regulation of prostate epithelial dynamics.

    Modelling the distinct roles of epithelial and stromal androgen receptor in the regulation of prostate epithelial dynamics.
    Woodman IL.

    02/21/2024
    Implication of androgen receptor gene dysfunction in human Mullerian duct anomalies.

    Implication of androgen receptor gene dysfunction in human Müllerian duct anomalies.
    Li L, Chen S, Li S, Duan AH, Lu D, Chu C.

    02/21/2024
    Structural insights into the mechanism of resistance to bicalutamide by the clinical mutations in androgen receptor in chemo-treatment resistant prostate cancer.

    Structural insights into the mechanism of resistance to bicalutamide by the clinical mutations in androgen receptor in chemo-treatment resistant prostate cancer.
    Majeed A, Tahir Ul Qamar M, Maryam A, Mirza MU, Alhussain L, Al Otaibi SO, Almatroudi A, Allemailem KS, Alrumaihi F, Aloliqi AA, Alshehri FF.

    02/16/2024
    A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells.

    A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells.
    Kalyanaraman H, Casteel DE, China SP, Zhuang S, Boss GR, Pilz RB., Free PMC Article

    02/8/2024
    ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.

    ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.
    Mazzeo L, Ghosh S, Di Cicco E, Isma J, Tavernari D, Samarkina A, Ostano P, Youssef MK, Simon C, Dotto GP., Free PMC Article

    02/7/2024
    Two somatic mutations in the androgen receptor N-terminal domain are oncogenic drivers in hepatocellular carcinoma.

    Two somatic mutations in the androgen receptor N-terminal domain are oncogenic drivers in hepatocellular carcinoma.
    Ren QN, Huang DH, Zhang XN, Wang YN, Zhou YF, Zhang MY, Wang SC, Mai SJ, Wu DH, Wang HY., Free PMC Article

    01/26/2024
    CAG and GGN repeat polymorphisms in the androgen receptor gene of a Chilean pediatric cohort with idiopathic inguinal cryptorchidism.

    CAG and GGN repeat polymorphisms in the androgen receptor gene of a Chilean pediatric cohort with idiopathic inguinal cryptorchidism.
    Rodríguez F, Godoy MJ, Ortiz E, Benítez-Filselcker A, López MT, Cassorla F, Castro A.

    01/16/2024
    Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis.

    Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis.
    Ramos RM, Petroli RJ, D'Alessandre NDR, Guardia GA, Afonso ACF, Nishi MY, Domenice S, Galante PAF, Mendonca BB, Batista RL.

    01/11/2024
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