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    IDO1 indoleamine 2,3-dioxygenase 1 [ Homo sapiens (human) ]

    Gene ID: 3620, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression and Prognostic Significance of LAG-3, TIGIT, VISTA, and IDO1 in Endometrial Serous Carcinoma.

    Expression and Prognostic Significance of LAG-3, TIGIT, VISTA, and IDO1 in Endometrial Serous Carcinoma.
    Chen H, Molberg K, Carrick K, Niu S, Rivera Colon G, Gwin K, Lewis C, Lea J, Panwar V, Zheng W, Castrillon DH, Lucas E.

    08/28/2024
    CD58 Alterations Govern Antitumor Immune Responses by Inducing PDL1 and IDO in Diffuse Large B-Cell Lymphoma.

    CD58 Alterations Govern Antitumor Immune Responses by Inducing PDL1 and IDO in Diffuse Large B-Cell Lymphoma.
    Xu X, Zhang Y, Lu Y, Zhang X, Zhao C, Wang J, Guan Q, Feng Y, Gao M, Yu J, Song Z, Liu X, Golchehre Z, Li L, Ren W, Pan-Hammarström Q, Zhang H, Wang X.

    08/14/2024
    PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.

    PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.
    Shu G, Chen M, Liao W, Fu L, Lin M, Gui C, Cen J, Lu J, Chen Z, Wei J, Chen W, Wang Y, Zhu J, Zhao T, Liu X, Jing J, Liu GC, Pan Y, Luo J, Zhang J., Free PMC Article

    07/8/2024
    Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.

    Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.
    Elomaa H, Härkönen J, Väyrynen SA, Ahtiainen M, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP.

    05/9/2024
    Indoleamine 2,3-Dioxygenase Deletion to Modulate Kynurenine Pathway and to Prevent Brain Injury after Cardiac Arrest in Mice.

    Indoleamine 2,3-Dioxygenase Deletion to Modulate Kynurenine Pathway and to Prevent Brain Injury after Cardiac Arrest in Mice.
    Magliocca A, Perego C, Motta F, Merigo G, Micotti E, Olivari D, Fumagalli F, Lucchetti J, Gobbi M, Mandelli A, Furlan R, Skrifvars MB, Latini R, Bellani G, Ichinose F, Ristagno G., Free PMC Article

    03/21/2024
    Low indoleamine 2, 3 dioxygenase (IDO) activity is associated with psycho-obstetric risk.

    Low indoleamine 2, 3 dioxygenase (IDO) activity is associated with psycho-obstetric risk.
    Gumusoglu S, Meincke CR, Kiel M, Betz A, Nuckols V, DuBose L, Steidele J, Sweezer E, Santillan D, Stroud AK, Pierce GL, Santillan MK.,

    03/12/2024
    IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.

    IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.
    Jing R, Bai S, Zhang P, Ren H, Jia L, Li W, Zheng G., Free PMC Article

    01/9/2024
    Expression of IDO1 in Tumor Microenvironment Significantly Predicts the Risk of Recurrence/Distant Metastasis for Patients With Esophageal Squamous Cell Carcinoma.

    Expression of IDO1 in Tumor Microenvironment Significantly Predicts the Risk of Recurrence/Distant Metastasis for Patients With Esophageal Squamous Cell Carcinoma.
    Qiu C, Lin Q, Ji S, Han C, Yang Q.

    01/3/2024
    Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non-Small Cell Lung Cancer.

    Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non-Small Cell Lung Cancer.
    Bessede A, Peyraud F, Le Moulec S, Cousin S, Cabart M, Chomy F, Rey C, Lara O, Odin O, Nafia I, Guegan JP, Italiano A., Free PMC Article

    12/5/2023
    IL-1beta mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells.

    IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells.
    Nawas AF, Solmonson A, Gao B, DeBerardinis RJ, Minna JD, Conacci-Sorrell M, Mendelson CR., Free PMC Article

    11/27/2023
    Elevated indoleamine 2,3-dioxygenase activity is associated with endothelial dysfunction in people living with HIV and ROS production in human aortic endothelial cells in vitro.

    Elevated indoleamine 2,3-dioxygenase activity is associated with endothelial dysfunction in people living with HIV and ROS production in human aortic endothelial cells in vitro.
    Yang J, Cai R, Xun J, Zhang R, Liu L, Shen Y, Qi T, Wang Z, Song W, Tang Y, Sun J, Xu S, Zhao B, Lu H, Chen J.

    11/22/2023
    Human Synovial Mesenchymal Stem Cells Expressed Immunoregulatory Factors IDO and TSG6 in a Context of Arthritis Mediated by Alphaviruses.

    Human Synovial Mesenchymal Stem Cells Expressed Immunoregulatory Factors IDO and TSG6 in a Context of Arthritis Mediated by Alphaviruses.
    Payet M, Septembre-Malaterre A, Gasque P, Guillot X., Free PMC Article

    11/18/2023
    Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer.

    Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer.
    Hoffmann I, Dragomir MP, Monjé N, Keunecke C, Kunze CA, Schallenberg S, Marchenko S, Schmitt WD, Kulbe H, Sehouli J, Braicu IE, Jank P, Denkert C, Darb-Esfahani S, Horst D, Sinn BV, Sers C, Bischoff P, Taube ET., Free PMC Article

    10/11/2023
    Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency Inhibits Pathological Cardiac Hypertrophy.

    Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency Inhibits Pathological Cardiac Hypertrophy.
    Wang Y, Song J, Yu K, Nie D, Zhao C, Jiao L, Wang Z, Zhou L, Wang F, Yu Q, Zhang S, Wen Z, Wu J, Wang CY, Wang DW, Cheng J, Zhao C.

    09/27/2023
    Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection.

    Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection.
    Cortez V, Livingston B, Sharp B, Hargest V, Papizan JB, Pedicino N, Lanning S, Jordan SV, Gulman J, Vogel P, DuBois RM, Crawford JC, Boyd DF, Pruett-Miller SM, Thomas PG, Schultz-Cherry S., Free PMC Article

    08/16/2023
    IL4i1 and IDO1: Oxidases that control a tryptophan metabolic nexus in cancer.

    IL4i1 and IDO1: Oxidases that control a tryptophan metabolic nexus in cancer.
    Zeitler L, Murray PJ., Free PMC Article

    07/7/2023
    High Indoleamine 2,3-Dioxygenase Expression along with Low Bridging Integrator-1 Expression in Hepatocellular Carcinoma Patients.

    High Indoleamine 2,3-Dioxygenase Expression along with Low Bridging Integrator-1 Expression in Hepatocellular Carcinoma Patients.
    Asghar K, Rana IA, Abubakar M, Hasham K, Tahseen M, Bilal S, Mehmood S, Farooq A, Siddique K, Loya A., Free PMC Article

    06/2/2023
    The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression.

    The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression.
    Chen H, Huang X, Zeng C, Sun D, Liu F, Zhang J, Liao Q, Luo S, Xu W, Xiao Y, Zeng D, Song M, Tian F., Free PMC Article

    03/16/2023
    Expression of IDO1 and PD-L2 in Patients with Benign Lymphadenopathies and Association with Autoimmune Diseases.

    Expression of IDO1 and PD-L2 in Patients with Benign Lymphadenopathies and Association with Autoimmune Diseases.
    Abdulla M, Sundström C, Lindskog C, Hollander P., Free PMC Article

    03/1/2023
    Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.

    Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
    Yang Y, Jin Y, Yin L, Liu P, Zhu L, Gao H.

    02/14/2023
    Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy.

    Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy.
    Wang R, Zhao S, Chen X, Xiao Z, Wen X, Zhong X, Li S, Cheng H, Huang G., Free PMC Article

    01/11/2023
    Expression of Inhibitory Molecules (Arginase-1, IDO, and PD-L1) by Myeloid-Derived Suppressor Cells in Multiple Myeloma Patients in Remission.

    Expression of Inhibitory Molecules (Arginase-1, IDO, and PD-L1) by Myeloid-Derived Suppressor Cells in Multiple Myeloma Patients in Remission.
    Tyrinova TV, Batorov EV, Aristova TA, Ushakova GY, Sizikova SA, Denisova VV, Ostanin AA, Chernykh ER.

    12/17/2022
    IDO1 Modulates the Sensitivity of Epithelial Ovarian Cancer Cells to Cisplatin through ROS/p53-Dependent Apoptosis.

    IDO1 Modulates the Sensitivity of Epithelial Ovarian Cancer Cells to Cisplatin through ROS/p53-Dependent Apoptosis.
    Wang H, Luo Y, Ran R, Li X, Ling H, Wen F, Yu T., Free PMC Article

    10/22/2022
    Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease.

    Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease.
    Török N, Maszlag-Török R, Molnár K, Szolnoki Z, Somogyvári F, Boda K, Tanaka M, Klivényi P, Vécsei L.

    10/22/2022
    Tryptophan degradation enzymes and Angiotensin (1-7) expression in human placenta.

    Tryptophan degradation enzymes and Angiotensin (1-7) expression in human placenta.
    Silvano A, Seravalli V, Strambi N, Tartarotti E, Tofani L, Calosi L, Parenti A, Di Tommaso M.

    10/8/2022
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