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    IL7R interleukin 7 receptor [ Homo sapiens (human) ]

    Gene ID: 3575, updated on 12-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.

    Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.
    Russell J, Chen L, Liu A, Wang J, Ghosh S, Zhong X, Shi H, Beutler B, Nair-Gill E., Free PMC Article

    08/21/2024
    PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression.

    PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression.
    Xu Y, Zhou Q, Wang X, Zhang A, Qi W, Li Y, Zheng C, Guan J, Sun T, Li J, Lu C, Shen Y, Zhao B., Free PMC Article

    07/8/2024
    Mechanism of co-operation of mutant IL-7Ralpha and mutant NRAS in acute lymphoblastic leukemia: role of MYC.

    Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC.
    Winer H, Li W, Rodrigues G, Gower T, Meyer TJ, Hixon J, Durum SK., Free PMC Article

    07/8/2024
    Type B thymomas in patients with myasthenia gravis display a distinctive pattern of alphabeta TCR and IL-7 receptor alpha expression on CD4[+]CD8[+] thymocytes.

    Type B thymomas in patients with myasthenia gravis display a distinctive pattern of αβ TCR and IL-7 receptor α expression on CD4(+)CD8(+) thymocytes.
    Wang T, Wang B, Fan X, Cai Y, Li L, Fu S.

    06/5/2024
    Investigation of the IL7Ralpha Gene Polymorphism rs6897932 and the Expression Levels of the CDH1, TTPAL, and FHIT Genes in Patients with Breast Cancer.

    Investigation of the IL7Rα Gene Polymorphism rs6897932 and the Expression Levels of the CDH1, TTPAL, and FHIT Genes in Patients with Breast Cancer.
    Arikan-Soylemez ES, Çilekar M, Akici M, Tokyol Ç, Özyürek HA, Söylemez Z, Solak M.

    12/29/2023
    A novel 268 kb deletion combined with a splicing variant in IL7R causes of severe combined immunodeficiency in a Chinese family: a case report.

    A novel 268 kb deletion combined with a splicing variant in IL7R causes of severe combined immunodeficiency in a Chinese family: a case report.
    Yan L, He Y, Zhang Y, Liu Y, Xu L, Han C, Zhao Y, Li H., Free PMC Article

    12/20/2023
    IL7RA rs10491434 polymorphism is related to spontaneous HIV infection control in naive HIV-infected patients: A retrospective study.

    IL7RA rs10491434 polymorphism is related to spontaneous HIV infection control in naïve HIV-infected patients: A retrospective study.
    Sepúlveda-Crespo D, Jiménez-Sousa MA, Fernández-Rodíguez A, Muñoz-Fernández MA, Jiménez JL, Caraciolo BB, Reus Bañuls S, Vilchez H, Mothe B, Martínez I, Benito JM, Rallón N, Resino S.

    11/21/2023
    Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients.

    Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients.
    Acheampong I, Minadzi D, Adankwah E, Aniagyei W, Vivekanandan MM, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Laing EF, Batsa Debrah L, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.

    09/28/2023
    Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma.

    Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma.
    Fu D, Yan J, Zhang Z, Liu Y, Ma X, Ding J, Yang S, Zhao R, Chang A, Gao C, Liu J, Zhao T, Wang X, Huang C, Gao S, Ma Y, Tang B, Feng Y, Wang H, Hao J., Free PMC Article

    09/8/2023
    The Therapeutic Values of IL-7/IL-7R and the Recombinant Derivatives in Glioma: A Narrative Review.

    The Therapeutic Values of IL-7/IL-7R and the Recombinant Derivatives in Glioma: A Narrative Review.
    Hesari M, Attar Z, Soltani-Shirazi S, Keshavarzian O, Taheri R, Tabrizi R, Fouladseresht H.

    08/17/2023
    CD4+CD25+CD127[lo]FOXP3+ cell in food allergy: Does it predict anaphylaxis?

    CD4+CD25+CD127(lo)FOXP3+ cell in food allergy: Does it predict anaphylaxis?
    Erdem SB, Genel F, Nacaroglu HT, Karaman S, Karkıner CSU, Sürücü M, Can D.

    06/2/2023
    IL-7 and IL-7R in health and disease: An update through COVID times.

    IL-7 and IL-7R in health and disease: An update through COVID times.
    Fernandes MB, Barata JT.

    03/7/2023
    In patients with primary Sjogren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-gamma, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells.

    In patients with primary Sjögren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells.
    Hinrichs AC, Kruize AA, Leavis HL, van Roon JAG., Free PMC Article

    01/11/2023
    Computational studies reveal co-occurrence of two mutations in IL7R gene of high-grade serous carcinoma patients.

    Computational studies reveal co-occurrence of two mutations in IL7R gene of high-grade serous carcinoma patients.
    Wadapurkar RM, Sivaram A, Vyas R.

    01/7/2023
    Lnc-IL7R alleviates PM2.5-mediated cellular senescence and apoptosis through EZH2 recruitment in chronic obstructive pulmonary disease.

    Lnc-IL7R alleviates PM(2.5)-mediated cellular senescence and apoptosis through EZH2 recruitment in chronic obstructive pulmonary disease.
    Lee KY, Ho SC, Sun WL, Feng PH, Lin CW, Chen KY, Chuang HC, Tseng CH, Chen TT, Wu SM.

    12/24/2022
    <i>IL7RA</i> single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection.

    IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection.
    Han F, Gulam MY, Zheng Y, Zulhaimi NS, Sia WR, He D, Ho A, Hadadi L, Liu Z, Qin P, Lobie PE, Kamarulzaman A, Wang LF, Sandberg JK, Lewin SR, Rajasuriar R, Leeansyah E., Free PMC Article

    11/12/2022
    IL-7 is expressed in malignant mesothelioma and has a prognostic value.

    IL-7 is expressed in malignant mesothelioma and has a prognostic value.
    Mai HL, Deshayes S, Nguyen TV, Dehame V, Chéné AL, Brouard S, Blanquart C., Free PMC Article

    10/29/2022
    The Role of IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy.

    The Role of IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy.
    Wang C, Kong L, Kim S, Lee S, Oh S, Jo S, Jang I, Kim TD., Free PMC Article

    10/8/2022
    IL-7/IL7R axis dysfunction in adults with severe community-acquired pneumonia (CAP): a cross-sectional study.

    IL-7/IL7R axis dysfunction in adults with severe community-acquired pneumonia (CAP): a cross-sectional study.
    Ampuero S, Bahamonde G, Tempio F, Garmendia ML, Ruiz M, Pizarro R, Rossi P, Huenchur L, Lizama L, López M, Avendaño LF, Luchsinger V., Free PMC Article

    08/13/2022
    Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21).

    Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21).
    Xu N, Sun K, Wang YZ, Chen WM, Wang J, Li LD, Wang X, Hao Y, Chang Y, Liu YR, Huang XJ, Qin YZ., Free PMC Article

    08/6/2022
    Antisense modulation of IL7R splicing to control sIL7R expression in human CD4(+) T cells.

    Antisense modulation of IL7R splicing to control sIL7R expression in human CD4(+) T cells.
    Galarza-Muñoz G, Kennedy-Boone D, Schott G, Bradrick SS, Garcia-Blanco MA., Free PMC Article

    07/23/2022
    Interaction of Interleukin 7 Receptor (IL7R) and IL6 Gene Polymorphisms with Smoking Associated with Susceptibility to Asthma in Chinese Han Adults.

    Interaction of Interleukin 7 Receptor (IL7R) and IL6 Gene Polymorphisms with Smoking Associated with Susceptibility to Asthma in Chinese Han Adults.
    Du JW, Xu ZL, Xu QX.

    07/23/2022
    Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in tuberculosis.

    Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in tuberculosis.
    Harelimana JD, Ahor HS, Benner B, Hellmuth S, Adankwah E, Minadzi D, Aniagyei W, Lamptey MNK, Arthur J, Yeboah A, Abass MK, Debrah LB, Owusu DO, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.

    06/11/2022
    An instructive role for Interleukin-7 receptor alpha in the development of human B-cell precursor leukemia.

    An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
    Geron I, Savino AM, Fishman H, Tal N, Brown J, Turati VA, James C, Sarno J, Hameiri-Grossman M, Lee YN, Rein A, Maniriho H, Birger Y, Zemlyansky A, Muler I, Davis KL, Marcu-Malina V, Mattson N, Parnas O, Wagener R, Fischer U, Barata JT, Jamieson CHM, Müschen M, Chen CW, Borkhardt A, Kirsch IR, Nagler A, Enver T, Izraeli S., Free PMC Article

    02/26/2022
    Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression.

    Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression.
    Semlali A, Almutairi MH, Alamri A, Reddy Parine N, Arafah M, Almadi MA, Aljebreen AM, Alharbi O, Azzam NA, Almutairi R, Alanazi M, Rouabhia M., Free PMC Article

    02/12/2022
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