Global IL4Rα blockade exacerbates heart failure after an ischemic event in mice and humans.
Alvarez-Argote S, Almeida VA, Knas MC, Buday SL, Patterson M, O'Meara CC.

Th2 cytokine signaling through IL-4Rα increases eotaxin-3 secretion and tension in human esophageal smooth muscle.
Nelson MR, Zhang X, Podgaetz E, Wang X, Zhang Q, Pan Z, Spechler SJ, Souza RF.

Association of IL4RA polymorphism in predicting susceptibility toward chronic obstructive pulmonary disease.
Pandit D, Sharma P, Yadav H, Garg K, Chopra V, Sharma S.

Association of the IL-4R Q576R Polymorphism with Pediatric Asthma: a meta-analysis.
Chen X, Hu J, Li K, Liu S, Ye Q, Cao B., Free PMC Article

Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer.
Li H, Cheng Z, Jiang B, Shao X, Xu M., Free PMC Article

IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases.
Aranda CJ, Gonzalez-Kozlova E, Saunders SP, Fernandes-Braga W, Ota M, Narayanan S, He JS, Del Duca E, Swaroop B, Gnjatic S, Shattner G, Reibman J, Soter NA, Guttman-Yassky E, Curotto de Lafaille MA., Free PMC Article

Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis.
Avlas S, Shani G, Rhone N, Itan M, Dolitzky A, Hazut I, Grisaru-Tal S, Gordon Y, Shoda T, Ballaban A, Ben-Baruch NM, Rochman M, Diesendruck Y, Nahary L, Bitton A, Halpern Z, Benhar I, Varol C, Rothenberg ME, Munitz A., Free PMC Article

Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children.
Banzon TM, Kelly MS, Bartnikas LM, Sheehan WJ, Cunningham A, Harb H, Crestani E, Valeri L, Greco KF, Chatila TA, Phipatanakul W, Lai PS., Free PMC Article

CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer.
Jiang T, Wang H, Liu L, Song H, Zhang Y, Wang J, Liu L, Xu T, Fan R, Xu Y, Wang S, Shi L, Zheng L, Wang R, Song J., Free PMC Article

Rab1A promotes IL-4R/JAK1/STAT6-dependent metastasis and determines JAK1 inhibitor sensitivity in non-small cell lung cancer.
Huang T, Chen B, Wang F, Cai W, Wang X, Huang B, Liu F, Jiang B, Zhang Y.

Associations of interleukin-4 and interleukin-4 receptor loci with esophageal squamous cell carcinoma susceptibility.
Wang J, Chen T, Tang W, Kang M, Chen S.

GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals.
Shido K, Kojima K, Shirota M, Yamasaki K, Motoike IN, Hozawa A, Ogishima S, Minegishi N, Tanno K, Katsuoka F, Tamiya G, Aiba S, Yamamoto M, Kinoshita K.

M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages.
Gunassekaran GR, Poongkavithai Vadevoo SM, Baek MC, Lee B.

Expression of IL4Rα and IL13Rα1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum.
Kim KM, Hussein UK, Park SH, Moon YJ, Zhang Z, Ahmed AG, Ahn AR, Park HS, Kim JR, Jang KY., Free PMC Article

Interrupting reactivation of immunologic memory diverts the allergic response and prevents anaphylaxis.
Bruton K, Spill P, Vohra S, Baribeau O, Manzoor S, Gadkar S, Davidson M, Walker TD, Koenig JFE, Ellenbogen Y, Florescu A, Wen J, Chu DK, Waserman S, Jiménez-Saiz R, Epelman S, Robbins C, Jordana M.

Interleukin 4 and Interleukin 4 receptor alpha gene variants and risk of atopy - A case control study based assessment.
Qurashi TA, Bhat GA, Khan MS, Rasool R, Sameen F, Hassan I, Mudassar S.

Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
Miranda E, Roberts J, Novick S, Lapointe JM, Bruijnzeel-Koomen C, Thijs J, Sleeman MA, May RD, Hijnen D, Strickland I.

Polymorphisms of interleukin 4 and interleukin 4 receptor genes and bronchial asthma risk among Egyptian children.
Elsaid A, Shoaib RMS, Badr SS, Wahba Y, Ayyad SN.

Polymorphisms of IL-4 and IL-4R are associated to some demographic characteristics of differentiated thyroid cancer patients but are not determinants of risk in the Brazilian population.
Martins MB, de Assis Batista F, Bufalo NE, Peres KC, Meneghetti M, da Assumpção LVM, Ward LS.

Blockade of IL-4Rα inhibits group 2 innate lymphoid cell responses in asthma patients.
Patel G, Pan J, Ye L, Shen X, Rosloff D, D'Souza SS, Fung ITH, Celstin J, Sun W, Sankar P, Zhang Y, Pasha MA, Yang Q., Free PMC Article

Detection of association of IL1β, IL4R, and IL6 gene polymorphisms with cervical cancer in the Bangladeshi women by tetra-primer ARMS-PCR method.
Muhammad SB, Hassan F, Bhowmik KK, Millat MS, Sarwar MS, Aziz MA, Barek MA, Sarowar Uddin M, Ferdous M, Safiqul Islam M.

Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer.
Shi J, Song X, Traub B, Luxenhofer M, Kornmann M., Free PMC Article

IL4RA gene expression in relation to I50V, Q551R and C-3223T polymorphisms.
Danielewicz H, Dębińska A, Drabik-Chamerska A, Kalita D, Boznański A.

IL-4R is expressed on alpha and beta cells of human pancreata.
Rajendran S, Graef M, Chu T, von Herrath M., Free PMC Article

The role of interleukin 4 and IL-4RA in intervertebral disc degeneration: investigation of single nucleotide polymorphisms in genes and a systematic review & meta-analysis of IL-4 expression level.
Hanaei S, Abdollahzade S, Sadr M, Mirbolouk MH, Fattahi E, Khoshnevisan A, Rezaei N.