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    IL4 interleukin 4 [ Homo sapiens (human) ]

    Gene ID: 3565, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of NLRP3 and IL-4 VNTR polymorphisms and genetic susceptibility to preeclampsia: A case-control study.

    Association of NLRP3 and IL-4 VNTR polymorphisms and genetic susceptibility to preeclampsia: A case-control study.
    Che M, Xu Y, Zang Y, Zhang R, Hu J, Liu S, Zhang J.

    11/6/2024
    Nasal mucosal fibroblasts produce IL-4 to induce Th2 response.

    Nasal mucosal fibroblasts produce IL-4 to induce Th2 response.
    Zeng X, Li J, Liu J, Mo L, Liu Y, Zhang A, Yang P, Kong H., Free PMC Article

    10/30/2024
    The aryl hydrocarbon receptor shapes monocyte transcriptional responses to interleukin-4 by prolonging STAT6 binding to promoters.

    The aryl hydrocarbon receptor shapes monocyte transcriptional responses to interleukin-4 by prolonging STAT6 binding to promoters.
    de Juan A, Tabtim-On D, Coillard A, Becher B, Goudot C, Segura E.

    10/25/2024
    A call for clinical trials in glioblastoma multiforme for interleukin 4, interleukin 6, interleukin 13 and CD40.

    A call for clinical trials in glioblastoma multiforme for interleukin 4, interleukin 6, interleukin 13 and CD40.
    Aydin S, Darko K, Detchou D, Barrie U.

    09/14/2024
    Increased level of GATA3-AS1 long non-coding RNA is correlated with the upregulation of GATA3 and IL-4 genes in multiple sclerosis patients.

    Increased level of GATA3-AS1 long non-coding RNA is correlated with the upregulation of GATA3 and IL-4 genes in multiple sclerosis patients.
    Keshavarz F, Mokhtari MJ, Poursadeghfard M.

    09/9/2024
    PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus.

    PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus.
    Tchen J, Simon Q, Chapart L, Thaminy MK, Vibhushan S, Saveanu L, Lamri Y, Saidoune F, Pacreau E, Pellefigues C, Bex-Coudrat J, Karasuyama H, Miyake K, Hidalgo J, Fallon PG, Papo T, Blank U, Benhamou M, Hanouna G, Sacre K, Daugas E, Charles N., Free PMC Article

    05/7/2024
    Association of IL-4 polymorphism with severe periodontitis in a sample of Iraqi population.

    Association of IL-4 polymorphism with severe periodontitis in a sample of Iraqi population.
    Najah A, Fadhil R, Akram HM, Salah R.

    05/3/2024
    IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4.

    IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4.
    Hils M, Hoffard N, Iuliano C, Kreft L, Chakrapani N, Swiontek K, Fischer K, Eberlein B, Köberle M, Fischer J, Hilger C, Ohnmacht C, Kaesler S, Wölbing F, Biedermann T., Free PMC Article

    04/15/2024
    The association of 25(OH)D, interleukin-4, interleukin-5, and interleukin-13 levels with the burden of soil-transmitted helminth infection in stunted children aged 24-59 months.

    The association of 25(OH)D, interleukin-4, interleukin-5, and interleukin-13 levels with the burden of soil-transmitted helminth infection in stunted children aged 24-59 months.
    Adrizain R, Nagari MV, Setiabudi D, Berbudi A, Setiabudiawan B.

    03/22/2024
    Interleukin-4 and Interleukin-17 are associated with coronary artery disease.

    Interleukin-4 and Interleukin-17 are associated with coronary artery disease.
    Wang C, Liu S, Yang Y, Kamronbek R, Ni S, Cheng Y, Zhou C, Yan H, Li L, Liu H, Wang Y, Qin Y, Yin C, Zhang M., Free PMC Article

    02/28/2024
    Linking adipose tissue eosinophils, IL-4, and leptin in human obesity and insulin resistance.

    Linking adipose tissue eosinophils, IL-4, and leptin in human obesity and insulin resistance.
    Hernandez JD, Li T, Ghannam H, Rau CM, Masuda MY, Madura JA 2nd, Jacobsen EA, De Filippis E., Free PMC Article

    02/14/2024
    Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder.

    Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder.
    Sarmin N, Roknuzzaman ASM, Mouree TZ, Islam MR, Al Mahmud Z., Free PMC Article

    01/31/2024
    Expression of miR-21 &IL-4 in endometriosis.

    Expression of miR-21 &IL-4 in endometriosis.
    Sadat Sandoghsaz R, Montazeri F, Shafienia H, Mehdi Kalantar S, Javaheri A, Samadi M.

    01/29/2024
    An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.

    An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.
    LaMarche NM, Hegde S, Park MD, Maier BB, Troncoso L, Le Berichel J, Hamon P, Belabed M, Mattiuz R, Hennequin C, Chin T, Reid AM, Reyes-Torres I, Nemeth E, Zhang R, Olson OC, Doroshow DB, Rohs NC, Gomez JE, Veluswamy R, Hall N, Venturini N, Ginhoux F, Liu Z, Buckup M, Figueiredo I, Roudko V, Miyake K, Karasuyama H, Gonzalez-Kozlova E, Gnjatic S, Passegué E, Kim-Schulze S, Brown BD, Hirsch FR, Kim BS, Marron TU, Merad M., Free PMC Article

    01/17/2024
    IL-4-secreting CD40L[+] MAIT cells support antibody production in the peripheral blood of Heonch-Schonlein purpura patients.

    IL-4-secreting CD40L(+) MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients.
    Liu M, Yang Z, Wu Q, Yang Y, Zhao D, Cheng Q, Li Y, Liu G, Zhao C, Pan J, Zhang Y, Deng F, Jin T.

    01/12/2024
    Akt, IL-4, and STAT Proteins Play Distinct Roles in Prostaglandin Production in Human Follicular Dendritic Cell-like Cells.

    Akt, IL-4, and STAT Proteins Play Distinct Roles in Prostaglandin Production in Human Follicular Dendritic Cell-like Cells.
    Jeong J, Choe J., Free PMC Article

    12/20/2023
    Association of MIF-173G/C, IL-4 VNTR, and IL-1RA VNTR variants with FMF-related amyloidosis in a Turkish cohort.

    Association of MIF-173G/C, IL-4 VNTR, and IL-1RA VNTR variants with FMF-related amyloidosis in a Turkish cohort.
    Yigit S, Nursal AF, Keskin A, Kaya S, Kuruca N, Sezer O.

    12/20/2023
    Pro-Fibrotic Role of Interleukin-4 in Influencing Idiopathic Epiretinal Membrane in Cataract Patients: Analysis From Clinical-Experimental Approaches.

    Pro-Fibrotic Role of Interleukin-4 in Influencing Idiopathic Epiretinal Membrane in Cataract Patients: Analysis From Clinical-Experimental Approaches.
    Song P, Li P, Huang Z, Yuan Y, Wei M, Wang C, Zhang G, Ji M, Guan H., Free PMC Article

    12/1/2023
    IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages.

    IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages.
    Scott TE, Lewis CV, Zhu M, Wang C, Samuel CS, Drummond GR, Kemp-Harper BK., Free PMC Article

    11/14/2023
    Intestinal flora altered and correlated with interleukin-2/4 in patients with primary immune thrombocytopenia.

    Intestinal flora altered and correlated with interleukin-2/4 in patients with primary immune thrombocytopenia.
    Wang H, Bi H, Yang M, Wang X, Song C, Yang W, Wang Y, Xie D, Li H, Zhou Z.

    11/10/2023
    IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development.

    IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development.
    Guedes JR, Ferreira PA, Costa J, Laranjo M, Pinto MJ, Reis T, Cardoso AM, Lebre C, Casquinha M, Gomes M, Shkatova V, Pereira M, Beltrão N, Hanuscheck N, Greenhalgh AD, Vogelaar CF, Carvalho AL, Zipp F, Cardoso AL, Peça J.

    11/6/2023
    A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13.

    A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13.
    Junior JDES, de Souza JL, da Silva LS, da Silva CC, do Nascimento TA, de Souza MLG, da Cunha AF, Batista JDS, Neto JPM, Guerra MVF, Ramasawmy R., Free PMC Article

    11/3/2023
    Characterization of peripheral blood T follicular helper (TFH) cells in patients with type 1 Gaucher disease and carriers.

    Characterization of peripheral blood T follicular helper (TFH) cells in patients with type 1 Gaucher disease and carriers.
    Uzen R, Bayram F, Dursun H, Kardas F, Cakir M, Cucer N, Eken A, Donmez-Altuntas H.

    10/28/2023
    Anti-dsDNA IgE induces IL-4 production from basophils, potentially involved in B-cell differentiation in systemic lupus erythematosus.

    Anti-dsDNA IgE induces IL-4 production from basophils, potentially involved in B-cell differentiation in systemic lupus erythematosus.
    Fujimoto S, Arinobu Y, Miyawaki K, Ayano M, Mitoma H, Kimoto Y, Ono N, Akashi K, Horiuchi T, Niiro H.

    10/5/2023
    Interleukin-4 Promotes Human Metapneumovirus Replication Through the JAK/STAT6 Pathway.

    Interleukin-4 Promotes Human Metapneumovirus Replication Through the JAK/STAT6 Pathway.
    Zhang Y, Wu G, Yang Y, Niu L, Zhao Y.

    09/21/2023
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