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    IGFBP2 insulin like growth factor binding protein 2 [ Homo sapiens (human) ]

    Gene ID: 3485, updated on 13-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.

    Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
    Quesnel MJ, Labonté A, Picard C, Zetterberg H, Blennow K, Brinkmalm A, Villeneuve S, Poirier J, Alzheimer’s Disease Neuroimaging Initiative, PREVENT-AD Research Group.,

    05/7/2024
    Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition.

    Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition.
    Zheng Y, Li W, Huang Y, Cheng H.

    04/25/2024
    The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway.

    The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway.
    Qian S, Wang F, Liao W, Liu J.

    03/22/2024
    Role of increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study.

    Role of increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study.
    Ji L, Jiao Z, Zhang L, Shi J, Wan Q, Qian C, Wang H, Cao X, Shen B, Jiang L., Free PMC Article

    03/8/2024
    Cancer-associated fibroblast-associated gene IGFBP2 promotes glioma progression through induction of M2 macrophage polarization.

    Cancer-associated fibroblast-associated gene IGFBP2 promotes glioma progression through induction of M2 macrophage polarization.
    Zhang X, Sun X, Guo C, Li J, Liang G.

    01/10/2024
    METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression.

    METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression.
    Wu Z, Wei N., Free PMC Article

    12/1/2023
    Insulin-like growth factor binding protein-2 as a biomarker for lupus nephritis.

    Insulin-like growth factor binding protein-2 as a biomarker for lupus nephritis.
    Luong PT, Nguyen TTD, Nguyen NT, Ngo HT, Nguyen HN, Pho DH, Nguyen HT.

    11/6/2023
    Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy.

    Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy.
    Yu W, Gao H, Hu T, Tan X, Liu Y, Liu H, He S, Chen Z, Guo S, Huang J., Free PMC Article

    11/3/2023
    Plasma IGFBP-2 levels reveal heterogeneity in hepatic fat content in adults with excess visceral adiposity.

    Plasma IGFBP-2 levels reveal heterogeneity in hepatic fat content in adults with excess visceral adiposity.
    Rauzier C, Chartrand DJ, Alméras N, Lemieux I, Larose E, Mathieu P, Pibarot P, Lamarche B, Rhéaume C, Poirier P, Després JP, Picard F., Free PMC Article

    11/1/2023
    Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients.

    Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients.
    Harland AJ, Perks CM, White P, Kurian KM, Barber HR., Free PMC Article

    07/23/2023
    IGFBP2 secretion by mammary adipocytes limits breast cancer invasion.

    IGFBP2 secretion by mammary adipocytes limits breast cancer invasion.
    Conway JRW, Dinç DD, Follain G, Paavolainen O, Kaivola J, Boström P, Hartiala P, Peuhu E, Ivaska J., Free PMC Article

    07/20/2023
    Associations of insulin-like growth factor binding protein-2 with metabolic profile and hepatic fat deposition in asymptomatic men and women.

    Associations of insulin-like growth factor binding protein-2 with metabolic profile and hepatic fat deposition in asymptomatic men and women.
    Rauzier C, Chartrand DJ, Alméras N, Lemieux I, Larose E, Mathieu P, Pibarot P, Lamarche B, Rhéaume C, Poirier P, Després JP, Picard F.

    07/3/2023
    Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis.

    Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis.
    Chin C, Ravichandran R, Sanborn K, Fleming T, Wheatcroft SB, Kearney MT, Tokman S, Walia R, Smith MA, Flint DJ, Mohanakumar T, Bremner RM, Sureshbabu A., Free PMC Article

    03/31/2023
    Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men.

    Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men.
    Rauzier C, Lamarche B, Tremblay AJ, Couture P, Picard F., Free PMC Article

    10/29/2022
    IGFBP2 function as a novel biomarker for active lupus nephritis.

    IGFBP2 function as a novel biomarker for active lupus nephritis.
    Li H, Liang J, Gao Y, Liu M, Xia N, Kong W, Zheng L, Zhang Y, Li Z, Chen H, Liu S, Sun L., Free PMC Article

    10/1/2022
    Reduced IGFBP-2 related immunoreactivity in human serum correlates with arterial stiffness in a healthy Chinese population.

    Reduced IGFBP-2 related immunoreactivity in human serum correlates with arterial stiffness in a healthy Chinese population.
    Jin B, Bai X, Yu K, Han L, Wang N, Han W.

    09/24/2022
    Prognostic value of IGFBP2 in various cancers: a systematic review and meta-analysis.

    Prognostic value of IGFBP2 in various cancers: a systematic review and meta-analysis.
    Zhang B, Hong CQ, Luo YH, Wei LF, Luo Y, Peng YH, Xu YW., Free PMC Article

    08/27/2022
    IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2.

    IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2.
    Jaipuria G, Shet D, Malik S, Swain M, Atreya HS, Galea CA, Slomiany MG, Rosenzweig SA, Forbes BE, Norton RS, Mondal S., Free PMC Article

    08/13/2022
    Prognostic impact of insulin-like growth factor-I and its binding proteins, insulin-like growth factor-I binding protein-2 and -3, on adverse histopathological features and survival outcomes after radical cystectomy.

    Prognostic impact of insulin-like growth factor-I and its binding proteins, insulin-like growth factor-I binding protein-2 and -3, on adverse histopathological features and survival outcomes after radical cystectomy.
    Sari Motlagh R, Schuettfort VM, Mori K, Katayama S, Rajwa P, Aydh A, Grossmann NC, Laukhtina E, Pradere B, Mostafai H, Quhal F, Abufaraj M, Lee R, Karakiewicz PI, Lotan Y, Comprate E, Moschini M, Gontero P, Shariat SF., Free PMC Article

    07/16/2022
    Insulin-like growth factor 2 mRNA-binding protein 2-regulated alternative splicing of nuclear factor 1 C-type causes excessive granulosa cell proliferation in polycystic ovary syndrome.

    Insulin-like growth factor 2 mRNA-binding protein 2-regulated alternative splicing of nuclear factor 1 C-type causes excessive granulosa cell proliferation in polycystic ovary syndrome.
    Zhao F, Wu L, Wang Q, Zhao X, Chen T, Yin C, Yan L, Yang X., Free PMC Article

    05/7/2022
    IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery.

    IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery.
    Faramia J, Hao Z, Mumphrey MB, Townsend RL, Miard S, Carreau AM, Nadeau M, Frisch F, Baraboi ED, Grenier-Larouche T, Noll C, Li M, Biertho L, Marceau S, Hould FS, Lebel S, Morrison CD, Münzberg H, Richard D, Carpentier AC, Tchernof A, Berthoud HR, Picard F., Free PMC Article

    03/5/2022
    SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2.

    SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2.
    Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S., Free PMC Article

    12/25/2021
    COL11A1 activates cancer-associated fibroblasts by modulating TGF-beta3 through the NF-kappaB/IGFBP2 axis in ovarian cancer cells.

    COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells.
    Wu YH, Huang YF, Chang TH, Chen CC, Wu PY, Huang SC, Chou CY.

    12/25/2021
    Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.

    Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.
    Fu L, Yuen KCJ, Tint AN, Hoffman AR, Bongso AT, Lee KO.

    12/18/2021
    Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells.

    Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells.
    Haschemi R, Kobelt D, Steinwarz E, Schlesinger M, Stein U, Bendas G., Free PMC Article

    12/18/2021
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