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    IFNG interferon gamma [ Homo sapiens (human) ]

    Gene ID: 3458, updated on 29-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    IFN-gamma induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.

    IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
    Wang S, Cheng T, Chen X, Zeng C, Qin W, Xu Y., Free PMC Article

    10/22/2024
    Interleukin-37 exacerbates liver inflammation and promotes IFN-gamma production in NK cells.

    Interleukin-37 exacerbates liver inflammation and promotes IFN-γ production in NK cells.
    Lin CI, Wang YW, Su KY, Chuang YH.

    10/17/2024
    Cholesterol promotes IFNG mRNA expression in CD4[+] effector/memory cells by SGK1 activation.

    Cholesterol promotes IFNG mRNA expression in CD4(+) effector/memory cells by SGK1 activation.
    Hanin A, Comi M, Sumida TS, Hafler DA., Free PMC Article

    10/16/2024
    IL-17 and IFN-gamma-producing Respiratory Tissue-Resident Memory CD4 T Cells Persist for Decades in Adults Immunized as Children With Whole-Cell Pertussis Vaccines.

    IL-17 and IFN-γ-producing Respiratory Tissue-Resident Memory CD4 T Cells Persist for Decades in Adults Immunized as Children With Whole-Cell Pertussis Vaccines.
    McCarthy KN, Hone S, McLoughlin RM, Mills KHG., Free PMC Article

    10/2/2024
    Recurrent ocular toxoplasmosis is associated with interferon-gamma deficiency possibly due to genetic origin.

    Recurrent ocular toxoplasmosis is associated with interferon-gamma deficiency possibly due to genetic origin.
    Hautala NM, Joensuu M, Paakkola T, Glumoff V, Kettunen K, Saarela J, Siiskonen M, Chen Z, Pylkäs K, Hautala T., Free PMC Article

    09/23/2024
    FLI1 promotes IFN-gamma-induced kynurenine production to impair anti-tumor immunity.

    FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity.
    Chen E, Wu J, Huang J, Zhu W, Sun H, Wang X, Lin D, Li X, Shi D, Liu Z, Huang J, Chen M, Xie F, Deng W., Free PMC Article

    09/20/2024
    The effect of infection with Toxoplasma gondii in inducing interferon-gamma in breast cancer patients.

    The effect of infection with Toxoplasma gondii in inducing interferon-gamma in breast cancer patients.
    Azab Hameed F, Khalaf AK., Free PMC Article

    09/9/2024
    Comparative single-cell analysis reveals IFN-gamma as a driver of respiratory sequelae after acute COVID-19.

    Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19.
    Li C, Qian W, Wei X, Narasimhan H, Wu Y, Arish M, Cheon IS, Tang J, de Almeida Santos G, Li Y, Sharifi K, Kern R, Vassallo R, Sun J.

    08/16/2024
    Interferon-gamma induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease.

    Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease.
    Juliar BA, Stanaway IB, Sano F, Fu H, Smith KD, Akilesh S, Scales SJ, El Saghir J, Bhatraju PK, Liu E, Yang J, Lin J, Eddy S, Kretzler M, Zheng Y, Himmelfarb J, Harder JL, Freedman BS., Free PMC Article

    07/11/2024
    AIM2 inflammasome regulated by the IFN-gamma/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease.

    AIM2 inflammasome regulated by the IFN-γ/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease.
    Zhao Y, Liang B, Sheng S, Wang C, Jin B, Zhang X, Cheng Y, Shen C, Zheng F., Free PMC Article

    06/27/2024
    Implications of IFNgamma SNP rs2069705 in primary Sjogren's syndrome: transcriptional activation and B cell infiltration.

    Implications of IFNγ SNP rs2069705 in primary Sjögren's syndrome: transcriptional activation and B cell infiltration.
    Chen X, Li M, Li H, Liu M, Su J, Ji Y., Free PMC Article

    05/30/2024
    Association of the IFNG +874T/A Polymorphism with Symptomatic COVID-19 Susceptibility.

    Association of the IFNG +874T/A Polymorphism with Symptomatic COVID-19 Susceptibility.
    Sarges KML, Póvoa da Costa F, Santos EFD, Cantanhede MHD, da Silva R, Veríssimo AOL, Viana MNDSA, Rodrigues FBB, Leite MM, Torres MKDS, Bentes da Silva C, Brito MTFM, Silva ALSD, Henriques DF, Vallinoto IMVC, Viana GMR, Queiroz MAF, Vallinoto ACR, Santos EJMD., Free PMC Article

    05/16/2024
    Association between interferon-gamma (IFN-gamma) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis.

    Association between interferon-gamma (IFN-γ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis.
    Hu X, Lu X.

    04/29/2024
    Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-gamma and exerts a therapeutic effect in abortion-prone mice.

    Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice.
    Fang Z, Mao J, Huang J, Sun H, Lu X, Lei H, Dong J, Chen S, Wang X., Free PMC Article

    04/22/2024
    Interferon-gamma-induced GBP1 is an inhibitor of human papillomavirus 18.

    Interferon-γ-induced GBP1 is an inhibitor of human papillomavirus 18.
    Xu M, Lin MC, Li ZH., Free PMC Article

    04/22/2024
    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-gamma and TNF-alpha expression and its impact on disease severity.

    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-γ and TNF-α expression and its impact on disease severity.
    Abdeltawab MSA, Fateen M, Saad El-Din S, Elmessiery RM, Mohammady Mohamed O, Marzouk Sadek K, Medhat E, Hamed AMR.

    03/29/2024
    IFN-gamma induces apoptosis in gemcitabine-resistant pancreatic cancer cells.

    IFN‑γ induces apoptosis in gemcitabine‑resistant pancreatic cancer cells.
    Kong X, Cheng D, Xu X, Zhang Y, Li X, Pan W., Free PMC Article

    03/19/2024
    IFN-gamma decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3beta signaling pathway.

    IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
    Song M, Liu X, Shen W, Wang Z, Wu J, Jiang J, Liu Y, Xu T, Bian T, Zhang M, Sun W, Huang M, Ji N., Free PMC Article

    03/5/2024
    Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran.

    Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran.
    Jahanshahi S, Nejad HR, Kazemi B, Saeedi P.

    03/4/2024
    Spontaneous, persistent, T cell-dependent IFN-gamma release in patients who progress to Long Covid.

    Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid.
    Krishna BA, Lim EY, Metaxaki M, Jackson S, Mactavous L, NIHR BioResource, Lyons PA, Doffinger R, Bradley JR, Smith KGC, Sinclair J, Matheson NJ, Lehner PJ, Sithole N, Wills MR., Free PMC Article

    02/26/2024
    Human alveolar macrophages display marked hypo-responsiveness to IFN-gamma in both proteomic and gene expression analysis.

    Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis.
    Thiel BA, Lundberg KC, Schlatzer D, Jarvela J, Li Q, Shaw R, Reba SM, Fletcher S, Beckloff SE, Chance MR, Boom WH, Silver RF, Bebek G., Free PMC Article

    02/12/2024
    Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-gamma-Induced Gene Expression.

    Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-γ-Induced Gene Expression.
    Lazar I, Livneh I, Ciechanover A, Fabre B., Free PMC Article

    02/9/2024
    Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas.

    Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas.
    Rodrigues RR, Freitas VS, Alves PM, Almeida Freitas R, Souza LB, Andrade Santos PP.

    01/29/2024
    ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-gamma Secretion from CD8+ T Cells in Vitiligo.

    ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-γ Secretion from CD8+ T Cells in Vitiligo.
    Lee EJ, Kim JY, Yeo JH, Park S, Bae YJ, Kwon IJ, Seong SH, Lee J, Oh SH.

    01/27/2024
    Increased age-associated B cells in patients with acquired aplastic anemia correlate with IFN-gamma.

    Increased age-associated B cells in patients with acquired aplastic anemia correlate with IFN-γ.
    Solomou EE, Kattamis A, Symeonidis A, Sirinian C, Salamaliki C, Tzanoudaki M, Diamantopoulos P, Plakoula E, Palasopoulou M, Giannakoulas N, Kontandreopoulou CN, Kollia P, Viniou NA, Galanopoulos A, Liossis SN, Vassilopoulos G., Free PMC Article

    01/17/2024
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