| Integrative bulk and single-cell transcriptome profiling analysis reveals IFI27 as a novel interferon-stimulated gene in dengue. | Integrative bulk and single-cell transcriptome profiling analysis reveals IFI27 as a novel interferon-stimulated gene in dengue.
Jiang C, He C, Kan J, Guan H, Zhou T, Yang Y. | 05/30/2023 |
| Behcet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions. | Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions.
Oğuz AK, Oygür ÇŞ, Taşır S, Özdağ H, Akar MN., Free PMC Article | 05/1/2023 |
| IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. | IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.
Shojaei M, Shamshirian A, Monkman J, Grice L, Tran M, Tan CW, Teo SM, Rodrigues Rossi G, McCulloch TR, Nalos M, Raei M, Razavi A, Ghasemian R, Gheibi M, Roozbeh F, Sly PD, Spann KM, Chew KY, Zhu Y, Xia Y, Wells TJ, Senegaglia AC, Kuniyoshi CL, Franck CL, Dos Santos AFR, de Noronha L, Motamen S, Valadan R, Amjadi O, Gogna R, Madan E, Alizadeh-Navaei R, Lamperti L, Zuñiga F, Nova-Lamperti E, Labarca G, Knippenberg B, Herwanto V, Wang Y, Phu A, Chew T, Kwan T, Kim K, Teoh S, Pelaia TM, Kuan WS, Jee Y, Iredell J, O'Byrne K, Fraser JF, Davis MJ, Belz GT, Warkiani ME, Gallo CS, Souza-Fonseca-Guimaraes F, Nguyen Q, Mclean A, Kulasinghe A, Short KR, Tang B., Free PMC Article | 02/11/2023 |
| Knockdown of NEAT1 restricts dengue virus replication by augmenting interferon alpha-inducible protein 27 via the RIG-I pathway. | Knockdown of NEAT1 restricts dengue virus replication by augmenting interferon alpha-inducible protein 27 via the RIG-I pathway.
Saini J, Thapa U, Bandyopadhyay B, Vrati S, Banerjee A. | 02/10/2023 |
| MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection. | MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection.
Xie F, Zhang Y, Li J, Sun L, Zhang L, Qi M, Zhang S, Jian F, Li X, Li J, Ning C, Wang R., Free PMC Article | 08/27/2022 |
| ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF. | ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF.
Li X, Kolling FW, Aridgides D, Mellinger D, Ashare A, Jakubzick CV., Free PMC Article | 07/23/2022 |
| PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p. | PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p.
Zhang Y, Chen C, Liu Z, Guo H, Lu W, Hu W, Lin Z., Free PMC Article | 04/9/2022 |
| Interferon alpha-inducible protein 27 (IFI27) is a prognostic marker for pancreatic cancer based on comprehensive bioinformatics analysis. | Interferon alpha-inducible protein 27 (IFI27) is a prognostic marker for pancreatic cancer based on comprehensive bioinformatics analysis.
Huang S, Zhao J, Song J, Li Y, Zuo R, Sa Y, Ma Z, OuYang H., Free PMC Article | 02/19/2022 |
| IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infants. | IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infants.
Gao J, Zhu X, Wu M, Jiang L, Wang F, He S., Free PMC Article | 10/23/2021 |
| The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/beta-catenin signaling pathway. | The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway.
Deng R, Zuo C, Li Y, Xue B, Xun Z, Guo Y, Wang X, Xu Y, Tian R, Chen S, Liu Q, Chen J, Wang J, Huang X, Li H, Guo M, Wang X, Yang M, Wu Z, Wang J, Ma J, Hu J, Li G, Tang S, Tu Z, Ji H, Zhu H., Free PMC Article | 10/2/2021 |
| ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells. | ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells.
Xu L, Zu T, Li T, Li M, Mi J, Bai F, Liu G, Wen J, Li H, Brakebusch C, Wang X, Wu X., Free PMC Article | 06/26/2021 |
| IFI27/ISG12 Downregulates Estrogen Receptor alpha Transactivation by Facilitating Its Interaction With CRM1/XPO1 in Breast Cancer Cells. | IFI27/ISG12 Downregulates Estrogen Receptor α Transactivation by Facilitating Its Interaction With CRM1/XPO1 in Breast Cancer Cells.
Cervantes-Badillo MG, Paredes-Villa A, Gómez-Romero V, Cervantes-Roldán R, Arias-Romero LE, Villamar-Cruz O, González-Montiel M, Barrios-García T, Cabrera-Quintero AJ, Rodríguez-Gómez G, Cancino-Villeda L, Zentella-Dehesa A, León-Del-Río A., Free PMC Article | 05/22/2021 |
| Expression of IFI27 could differentiate athletes reporting upper respiratory symptoms from asymptomatic athletes | Key viral immune genes and pathways identify elite athletes with URS.
Colbey C, Drew MK, Cox AJ, Vider J, Pyne DB, Vlahonich N, Hughes D, Waddington G, Appaneal R, Burke LM, Lundy B, Toomey M, Watts D, Lovell G, Praet S, Halson SL, Welvaert M, Zhang P, Cripps AW, West NP. | 03/28/2020 |
| High IFI27 expression is associated with invasion in oral squamous cell carcinoma. | Knockdown of IFI27 inhibits cell proliferation and invasion in oral squamous cell carcinoma.
Wang H, Qiu X, Lin S, Chen X, Wang T, Liao T., Free PMC Article | 09/22/2018 |
| NEAT1 and the coding gene IFI27 were highly co-expressed and negatively correlated with dengue severity. Monitoring NEAT1and IFI27 expression in PBMC may be useful in understanding dengue virus-induced disease progression. | Correlation of altered expression of a long non-coding RNA, NEAT1, in peripheral blood mononuclear cells with dengue disease progression.
Pandey AD, Goswami S, Shukla S, Das S, Ghosal S, Pal M, Bandyopadhyay B, Ramachandran V, Basu N, Sood V, Pandey P, Chakrabarti J, Vrati S, Banerjee A. | 06/30/2018 |
| IFI27 was expressed in Influenza patients but not in Bacterial Respiratory Infection. IFI27 displayed 88% diagnostic accuracy (AUC) and 90% specificity in discriminating between Influenza and Bacterial Infections. | A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection.
Tang BM, Shojaei M, Parnell GP, Huang S, Nalos M, Teoh S, O'Connor K, Schibeci S, Phu AL, Kumar A, Ho J, Meyers AFA, Keynan Y, Ball T, Pisipati A, Kumar A, Moore E, Eisen D, Lai K, Gillett M, Geffers R, Luo H, Gul F, Schreiber J, Riedel S, Booth D, McLean A, Schughart K. | 04/7/2018 |
| ISG12a inhibited HCV replication and potentiated the anti-HCV activity of IFN-alpha possibly through induced production of type I IFNs and activation of Jak/STAT signaling pathway independent of autophagy and cell apoptosis. | ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis.
Chen Y, Jiao B, Yao M, Shi X, Zheng Z, Li S, Chen L. | 12/16/2017 |
| the ISG12 family of proteins has an important role for the apoptotic properties induced by type 1 interferon. | Apoptotic properties of the type 1 interferon induced family of human mitochondrial membrane ISG12 proteins.
Gytz H, Hansen MF, Skovbjerg S, Kristensen AC, Hørlyck S, Jensen MB, Fredborg M, Markert LD, McMillan NA, Christensen EI, Martensen PM. | 02/18/2017 |
| IFI27 mRNA level is reduced in peripheral blood mononuclear cells of immunoglobulin A nephropathy and membranous nephropathy patients. | IFI27 Is a Useful Genetic Marker for Diagnosis of Immunoglobulin A Nephropathy and Membranous Nephropathy Using Peripheral Blood.
Nagasawa Y, Okuzaki D, Muso E, Yamamoto R, Shinzawa M, Iwasaki Y, Iwatani H, Nakanishi T, Isaka Y, Nojima H., Free PMC Article | 09/3/2016 |
| IFI27 is involved in proliferation of skin keratinocytes both in vitro and in vivo. | IFI27, a novel epidermal growth factor-stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes.
Hsieh WL, Huang YH, Wang TM, Ming YC, Tsai CN, Pang JH., Free PMC Article | 06/20/2015 |
| Data indicate that AKT control TRAIL resistance of cancer cells through downregulation of interferon stimulated gene 12a (ISG12a) by MicroRNA-942 (miR-942). | miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT.
Liu N, Zuo C, Wang X, Chen T, Yang D, Wang J, Zhu H., Free PMC Article | 05/16/2015 |
| We found that IFI27 is overexpressed in ovarian cancer and associated with patients' survival. | Interferon alpha-inducible protein 27 promotes epithelial-mesenchymal transition and induces ovarian tumorigenicity and stemness.
Li S, Xie Y, Zhang W, Gao J, Wang M, Zheng G, Yin X, Xia H, Tao X. | 03/21/2015 |
| MiR-942 regulates hepatitis c virus-induced apoptosis of human hepatocytes by targeting ISG12a. | MiR-942 mediates hepatitis C virus-induced apoptosis via regulation of ISG12a.
Yang D, Meng X, Xue B, Liu N, Wang X, Zhu H., Free PMC Article | 01/17/2015 |
| These results suggest that high basal ISG12a may inhibit Newcastle disease virus replication and oncolysis, while low basal ISG12a may allow sufficient Newcastle disease virus replication for induction of ISG12a. | ISG12a mediates cell response to Newcastle disease viral infection.
Liu N, Long Y, Liu B, Yang D, Li C, Chen T, Wang X, Liu C, Zhu H. | 10/4/2014 |
| Alterations in mechanisms associated with immune response and mitochondrial function that explain the up-regulation of IFI27 may provide an understanding of the pathways related to the intensification of fatigue during localized radiation therapy. | The association of IFI27 expression and fatigue intensification during localized radiation therapy: implication of a para-inflammatory bystander response.
Hsiao CP, Araneta M, Wang XM, Saligan LN., Free PMC Article | 03/22/2014 |