STING-mediated degradation of IFI16 negatively regulates apoptosis by inhibiting p53 phosphorylation at serine 392.
Li D, Xie L, Qiao Z, Mai S, Zhu J, Zhang F, Chen S, Li L, Shen F, Qin Y, Yao H, He S, Ma F., Free PMC Article

Interferon-γ inducible factor 16 (IFI16) restricts adeno-associated virus type 2 (AAV2) transduction in an immune-modulatory independent way.
Sutter SO, Tobler K, Seyffert M, Lkharrazi A, Zöllig J, Schraner EM, Vogt B, Büning H, Fraefel C., Free PMC Article

IFI16 Positively Regulates RIG-I-Mediated Type I Interferon Production in a STING-Independent Manner.
Shi X, Wei M, Feng Y, Yang Y, Zhang X, Chen H, Xing Y, Wang K, Wang W, Wang L, Wang A, Zhang G.

IFI16 Is Indispensable for Promoting HIF-1α-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions.
Randle RK, Amara VR, Popik W., Free PMC Article

Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes.
Arunachalam LT, Suresh S, Lavu V, Vedamanickam S, Viswanathan S, Thirumalai Nathan RD.

IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1α.
Azumi Y, Koma YI, Tsukamoto S, Kitamura Y, Ishihara N, Yamanaka K, Nakanishi T, Miyako S, Urakami S, Tanigawa K, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H., Free PMC Article

Effects of AIM2 and IFI16 on Infectious Diseases and Inflammation.
Fan Z, Chen R, Yin W, Xie X, Wang S, Hao C.

IFI16 phase separation via multi-phosphorylation drives innate immune signaling.
Liu D, Lum KK, Treen N, Núñez CT, Yang J, Howard TR, Levine M, Cristea IM., Free PMC Article

IFI16/Ifi202 released from breast cancer induces secretion of inflammatory cytokines from macrophages and promotes tumor growth.
Lim GY, Cho SW, Ka NL, Lee KH, Im SA, Kim SS, Hwang S, Lee MO.

Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors.
Garg A, Stallings CM, Sohn J., Free PMC Article

Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil.
Neira-Goulart M, de Sá NBR, Ribeiro-Alves M, Perazzo H, Geraldo KM, Ribeiro MPD, Cardoso SW, Grinsztejn B, Veloso VG, Rodrigues Gomes L, Cazote ADS, de Almeida DV, Giacoia-Gripp CBW, Côrtes FH, Morgado MG., Free PMC Article

Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.
Wang J, Qin X, Huang Y, Zhang G, Liu Y, Cui Y, Wang Y, Pei J, Ma S, Song Z, Zhu X, Wang H, Yang B., Free PMC Article

ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.
Gao Z, Xu J, Fan Y, Zhang Z, Wang H, Qian M, Zhang P, Deng L, Shen J, Xue H, Zhao R, Zhou T, Guo X, Li G., Free PMC Article

IFI16 Partners with KAP1 to Maintain Epstein-Barr Virus Latency.
Xu H, Li X, Rousseau BA, Akinyemi IA, Frey TR, Zhou K, Droske LE, Mitchell JA, McIntosh MT, Bhaduri-McIntosh S., Free PMC Article

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer.
Ong LT, Lee WC, Ma S, Oguz G, Niu Z, Bao Y, Yusuf M, Lee PL, Goh JY, Wang P, Yong KSM, Chen Q, Wang W, Ramasamy A, Hoon DSB, Ditzel HJ, Tan EY, Lee SC, Yu Q., Free PMC Article

IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection.
Griffante G, Hewelt-Belka W, Albano C, Gugliesi F, Pasquero S, Castillo Pacheco SF, Bajetto G, Porporato PE, Mina E, Vallino M, Krapp C, Jakobsen MR, Purdy J, von Einem J, Landolfo S, Dell'Oste V, Biolatti M., Free PMC Article

HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.
Liu C, Li L, Hou G, Lu Y, Gao M, Zhang L.

The significance of interferon gamma inducible protein 16 (IFI16) expression in drug resistant ovarian cancer cell lines.
Borucka J, Sterzyńska K, Kaźmierczak D, Świerczewska M, Nowacka M, Wojtowicz K, Klejewski A, Nowicki M, Zabel M, Ramlau R, Januchowski R.

The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps.
Antiochos B, Trejo-Zambrano D, Fenaroli P, Rosenberg A, Baer A, Garg A, Sohn J, Li J, Petri M, Goldman DW, Mecoli C, Casciola-Rosen L, Rosen A., Free PMC Article

Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E(2)-dependent growth of ER-positive breast cancer.
Ka NL, Lim GY, Kim SS, Hwang S, Han J, Lee YH, Lee MO., Free PMC Article

IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway.
Liu L, Xie S, Li C, Guo Y, Liu X, Zhao X, Li Q, Du W., Free PMC Article

IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer.
Ka NL, Lim GY, Hwang S, Kim SS, Lee MO.

The Role of Inflammasome Activation in Early HIV Infection.
Ekabe CJ, Clinton NA, Kehbila J, Franck NC., Free PMC Article

Increased expression of IFI16 predicts adverse prognosis in multiple myeloma.
Huang W, Qian T, Huang Z, Liu Y, Cui L, Zhu P, Zhong Q, Zeng T, Fu L, Si C, Deng C.

The role of cyclic GMP-AMP synthase and Interferon-I-inducible protein 16 as candidatebiomarkers of systemic lupus erythematosus.
Fu Q, He Q, Dong Q, Xie J, Geng Y, Han H, Huang Y, Lu J, Zeng Z, Wang W, Chen K, Zhan X.