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    STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ]

    Gene ID: 340061, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    STING Orchestrates EV-D68 Replication and Immunometabolism within Viral-Induced Replication Organelles.

    STING Orchestrates EV-D68 Replication and Immunometabolism within Viral-Induced Replication Organelles.
    Triantafilou K, Szomolay B, Shepherd MW, Ramanjulu J, Triantafilou M., Free PMC Article

    11/4/2024
    Tumor phagocytosis-driven STING activation invigorates antitumor immunity and reprograms the tumor micro-environment.

    Tumor phagocytosis-driven STING activation invigorates antitumor immunity and reprograms the tumor micro-environment.
    Lee S, Hong KH, Park H, Ha J, Lee SE, Park DJ, Jeong SD, Kim S, Kim D, Ahn J, Lee HW, Koh WG, Ha SJ, Kim YC.

    10/30/2024
    The involvement of Sting in exacerbating acute lung injury in sepsis via the PARP-1/NLRP3 signaling pathway.

    The involvement of Sting in exacerbating acute lung injury in sepsis via the PARP-1/NLRP3 signaling pathway.
    Ying T, Yu Y, Yu Q, Zhou G, Chen L, Gu Y, Zhu L, Ying H, Chen M.

    10/29/2024
    A TBK1-independent primordial function of STING in lysosomal biogenesis.

    A TBK1-independent primordial function of STING in lysosomal biogenesis.
    Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX.,

    10/28/2024
    Unravelling the interplay between ER stress, UPR and the cGAS-STING pathway: Implications for osteoarthritis pathogenesis and treatment strategy.

    Unravelling the interplay between ER stress, UPR and the cGAS-STING pathway: Implications for osteoarthritis pathogenesis and treatment strategy.
    Soh LJ, Lee SY, Roebuck MM, Wong PF.

    10/25/2024
    STING Contributes to Pulmonary Hypertension by Targeting IFN and BMPR2 Signaling through Regulating of F2RL3.

    STING Contributes to Pulmonary Hypertension by Targeting IFN and BMPR2 Signaling through Regulating of F2RL3.
    Deng L, Cao C, Cai Z, Wang Z, Leng B, Chen Z, Kong F, Zhou Z, He J, Nie X, Bian JS.

    10/9/2024
    Inactivated cGAS-STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2- Breast Cancer.

    Inactivated cGAS-STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2- Breast Cancer.
    Zhang KM, Zhao DC, Li ZY, Wang Y, Liu JN, Du T, Zhou L, Chen YH, Yu QC, Chen QS, Cai RZ, Zhao ZX, Shan JL, Hu BX, Zhang HL, Feng GK, Zhu XF, Tang J, Deng R., Free PMC Article

    10/3/2024
    Activation of the cGAS-STING-IRF3 Axis by Type I and II Interferons Contributes to Host Defense.

    Activation of the cGAS-STING-IRF3 Axis by Type I and II Interferons Contributes to Host Defense.
    Tong Z, Zou JP, Wang SY, Luo WW, Wang YY., Free PMC Article

    10/3/2024
    FMT rescues mice from DSS-induced colitis in a STING-dependent manner.

    FMT rescues mice from DSS-induced colitis in a STING-dependent manner.
    Pu D, Yao Y, Zhou C, Liu R, Wang Z, Liu Y, Wang D, Wang B, Wang Y, Liu Z, Zhang Z, Feng B., Free PMC Article

    10/3/2024
    Hsa-miR-181a-2-3p inhibits the oncogenicity of colon cancer by directly targeting STING.

    Hsa-miR-181a-2-3p inhibits the oncogenicity of colon cancer by directly targeting STING.
    Liu B, Lu K, Yuan L, Li X, Lan L, Han S., Free PMC Article

    10/1/2024
    VPS13C and STING expression in neuropsychiatric systemic lupus erythematosus: unveiling an unbreached territory.

    VPS13C and STING expression in neuropsychiatric systemic lupus erythematosus: unveiling an unbreached territory.
    Ebaid AM, Zakaria MA, Mekkawy EM, Nageeb RS, Elfwakhry RM, Seleem DA, Shabana MA, Esawy MM., Free PMC Article

    09/30/2024
    The relationship between tumor immunity and the cGAS-STING pathway in breast cancer: An immunohistochemical study.

    The relationship between tumor immunity and the cGAS-STING pathway in breast cancer: An immunohistochemical study.
    Nishida H, Ohara N, Kato A, Kaimori R, Kondo Y, Kusaba T, Kadowaki H, Kawamura K, Daa T.

    09/29/2024
    High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8[+] T cells in dMMR/MSI-H gastric cancer.

    High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8(+) T cells in dMMR/MSI-H gastric cancer.
    Kanoda R, Nakajima S, Fukai S, Saito M, Saito K, Suzuki H, Kikuchi T, Nirei A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K., Free PMC Article

    09/16/2024
    53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer.

    53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer.
    Sun Y, Patterson-Fortin J, Han S, Li Z, Nowicka Z, Hirohashi Y, Kilgas S, Yi JK, Spektor A, Fendler W, Konstantinopoulos PA, Chowdhury D., Free PMC Article

    09/13/2024
    Targeting protein condensation in cGAS-STING signaling pathway.

    Targeting protein condensation in cGAS-STING signaling pathway.
    Li Y, Zhao D, Chen D, Sun Q.

    09/4/2024
    Microglial cGAS-STING signaling underlies glaucoma pathogenesis.

    Microglial cGAS-STING signaling underlies glaucoma pathogenesis.
    Liu Y, Wang A, Chen C, Zhang Q, Shen Q, Zhang D, Xiao X, Chen S, Lian L, Le Z, Liu S, Liang T, Zheng Q, Xu P, Zou J.,

    09/4/2024
    The crucial roles and research advances of cGAS-STING pathway in liver diseases.

    The crucial roles and research advances of cGAS‑STING pathway in liver diseases.
    Zhang X, He B, Lu J, Bao Q, Wang J, Yang Y., Free PMC Article

    08/31/2024
    STING-mediated degradation of IFI16 negatively regulates apoptosis by inhibiting p53 phosphorylation at serine 392.

    STING-mediated degradation of IFI16 negatively regulates apoptosis by inhibiting p53 phosphorylation at serine 392.
    Li D, Xie L, Qiao Z, Mai S, Zhu J, Zhang F, Chen S, Li L, Shen F, Qin Y, Yao H, He S, Ma F., Free PMC Article

    08/27/2024
    FASN regulates STING palmitoylation via malonyl-CoA in macrophages to alleviate sepsis-induced liver injury.

    FASN regulates STING palmitoylation via malonyl-CoA in macrophages to alleviate sepsis-induced liver injury.
    Kang J, Wu J, Liu Q, Jiang H, Li W, Li Y, Li X, Ni C, Wu L, Liu M, Liu H, Deng L, Lin Z, Wu X, Zhao Y, Ren J.

    08/22/2024
    Intestinal epithelial damage-derived mtDNA activates STING-IL12 axis in dendritic cells to promote colitis.

    Intestinal epithelial damage-derived mtDNA activates STING-IL12 axis in dendritic cells to promote colitis.
    Cai Y, Li S, Yang Y, Duan S, Fan G, Bai J, Zheng Q, Gu Y, Li X, Liu R., Free PMC Article

    08/9/2024
    The effects of cGAS-STING inhibition in liver disease, kidney disease, and cellular senescence.

    The effects of cGAS-STING inhibition in liver disease, kidney disease, and cellular senescence.
    Wang L, Zhang Z, Zhang H, Zhou M, Huang C, Xia W, Li J, You H., Free PMC Article

    08/9/2024
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection.

    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection.
    Ritchie C, Li L.,

    08/1/2024
    [Correlation Analysis between STING Promoter Polymorphism and Susceptibility to Infection after Chemotherapy for Multiple Myeloma].

    [Correlation Analysis between STING Promoter Polymorphism and Susceptibility to Infection after Chemotherapy for Multiple Myeloma].
    Huang ZP, Yang CH.

    07/16/2024
    Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma.

    Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma.
    Wu S, Wang B, Li H, Wang H, Du S, Huang X, Fan Y, Gao Y, Gu L, Huang Q, Chen J, Zhang X, Huang Y, Ma X.

    07/11/2024
    cGAS-STING-TBK1 Signaling Promotes Valproic Acid-Responsive Human Cytomegalovirus Immediate-Early Transcription during Infection of Incompletely Differentiated Myeloid Cells.

    cGAS-STING-TBK1 Signaling Promotes Valproic Acid-Responsive Human Cytomegalovirus Immediate-Early Transcription during Infection of Incompletely Differentiated Myeloid Cells.
    Albright ER, Kalejta RF., Free PMC Article

    07/5/2024
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