| NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis. | NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis.
Kharel P, Singhal NK, Mahendran T, West N, Croos B, Rana J, Smith L, Freeman E, Chattopadhyay A, McDonough J, Basu S. | 03/23/2023 |
| Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation. | Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation.
De Falco P, Lazzarino G, Felice F, Desideri E, Castelli S, Salvatori I, Ciccarone F, Ciriolo MR., Free PMC Article | 01/28/2023 |
| Investigating DNA Methylation of SHATI/NAT8L Promoter Sites in Blood of Unmedicated Patients with Major Depressive Disorder. | Investigating DNA Methylation of SHATI/NAT8L Promoter Sites in Blood of Unmedicated Patients with Major Depressive Disorder.
Miyanishi H, Uno K, Iwata M, Kikuchi Y, Yamamori H, Yasuda Y, Ohi K, Hashimoto R, Hattori K, Yoshida S, Goto YI, Sumiyoshi T, Nitta A. | 01/2/2021 |
| A Single Medical Marker for Diagnosis of Methamphetamine Addiction - DNA Methylation of SHATI/NAT8L Promoter Sites from Patient Blood. | A Single Medical Marker for Diagnosis of Methamphetamine Addiction - DNA Methylation of SHATI/NAT8L Promoter Sites from Patient Blood.
Yuka K, Nishizawa D, Hasegawa J, Uno K, Miyanishi H, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Ikeda K, Nitta A. | 11/21/2020 |
| Nat8l CpG island methylation ratios were lower in the patients with schizophrenia than in the healthy controls. | Decreased DNA Methylation in the Shati/Nat8l Promoter in Both Patients with Schizophrenia and a Methamphetamine-Induced Murine Model of Schizophrenia-Like Phenotype.
Uno K, Kikuchi Y, Iwata M, Uehara T, Matsuoka T, Sumiyoshi T, Okamoto Y, Jinno H, Takada T, Furukawa-Hibi Y, Nabeshima T, Miyamoto Y, Nitta A., Free PMC Article | 07/29/2017 |
| Characterization and recombinant expression of the nat8l gene that codes for ANAT. | Purification and characterization of aspartate N-acetyltransferase: A critical enzyme in brain metabolism.
Wang Q, Zhao M, Parungao GG, Viola RE. | 10/29/2016 |
| NAA is produced specifically in NSCLC tumors through NAT8L overexpression, and its extracellular secretion can be detected in blood | Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis C, Um SW, Kim DH, Ahn JM, DeBerardinis RJ, White MA, Minna JD, Yoo H., Free PMC Article | 10/22/2016 |
| This study demonistrated that the human NAT8L gene related to reward dependence, a personality trait, and grey matter volume in the caudate nucleus in healthy subjects, suggesting that NAT8L might also affect human personality | Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence.
Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T. | 09/20/2014 |
| Nat8l impacts on the brown adipogenic phenotype | NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Pessentheiner AR, Pelzmann HJ, Walenta E, Schweiger M, Groschner LN, Graier WF, Kolb D, Uno K, Miyazaki T, Nitta A, Rieder D, Prokesch A, Bogner-Strauss JG., Free PMC Article | 02/15/2014 |
| The aim of the present study was to determine which regions of the protein are important for its catalytic activity and its subcellular localization. | Determinants of the enzymatic activity and the subcellular localization of aspartate N-acetyltransferase.
Tahay G, Wiame E, Tyteca D, Courtoy PJ, Van Schaftingen E. | 02/18/2012 |
| Results indicated that NAT8L, but not NAT14, catalysed the synthesis of NAA from L-aspartate and acetyl-CoA. | Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.
Wiame E, Tyteca D, Pierrot N, Collard F, Amyere M, Noel G, Desmedt J, Nassogne MC, Vikkula M, Octave JN, Vincent MF, Courtoy PJ, Boltshauser E, van Schaftingen E. | 01/25/2010 |