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    C1QTNF9 C1q and TNF related 9 [ Homo sapiens (human) ]

    Gene ID: 338872, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Causal association between complement system FHR-5, CTRP9, and breast carcinoma in situ: a Mendelian randomization study.

    Causal association between complement system FHR-5, CTRP9, and breast carcinoma in situ: a Mendelian randomization study.
    Peng YL, Li H, Sun P, Zhang HD, Li D, Wang HB, Zhang L.

    04/8/2024
    CTRP9 alleviates hypoxia/reoxygenation-induced human placental vascular endothelial cells impairment and mitochondrial dysfunction through activating AMPK/Nrf2 signaling.

    CTRP9 alleviates hypoxia/reoxygenation-induced human placental vascular endothelial cells impairment and mitochondrial dysfunction through activating AMPK/Nrf2 signaling.
    Zhu L, Chen S, Dai X.

    11/16/2023
    Association Between Circulating Levels of C1q/TNF-Related Protein-9 and Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis.

    Association Between Circulating Levels of C1q/TNF-Related Protein-9 and Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis.
    Song R, Hu W, Cheng R, Zhao Y, Qin W, Li X, Zhu Y, Gan L, Liu J., Free PMC Article

    09/20/2023
    C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3beta-Nrf2 cascade via AdipoR1.

    C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
    Wang J, Ren B, Yang Y, Li Y.

    04/26/2023
    Increased Levels of ANGPTL3 and CTRP9 in Patients With Obstructive Sleep Apnea and Their Relation to Insulin Resistance and Lipid Metabolism and Markers of Endothelial Dysfunction.

    Increased Levels of ANGPTL3 and CTRP9 in Patients With Obstructive Sleep Apnea and Their Relation to Insulin Resistance and Lipid Metabolism and Markers of Endothelial Dysfunction.
    Fadaei R, Azadi SM, Laher I, Khazaie H.

    01/28/2023
    Serum CTRP9 and high-molecular weight adiponectin are associated with ischemic stroke.

    Serum CTRP9 and high-molecular weight adiponectin are associated with ischemic stroke.
    Zhang YQ, Zhang YW, Dai JL, Li C, Wang WQ, Zhang HF, Lau WB, Wang XM, Liu XG, Li R., Free PMC Article

    12/10/2022
    Novel Adipokines CTRP1, CTRP9, and FGF21 in Pediatric Type 1 and Type 2 Diabetes: A Cross-Sectional Analysis.

    Novel Adipokines CTRP1, CTRP9, and FGF21 in Pediatric Type 1 and Type 2 Diabetes: A Cross-Sectional Analysis.
    Arking A, Sarver DC, Magge SN, Wong GW, Wolf RM., Free PMC Article

    05/21/2022
    the long-term existence of beta1- AA mAb suppresses cardiac CTRP 9 expression and exaggerates cardiac remodeling, suggesting that CTRP 9 may be a novel therapeutic target against pathologic remodeling in beta1- AA -positive patients with coronary heart disease

    Autoantibodies Against β(1)-Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression.
    Du Y, Zhang S, Yu H, Wu Y, Cao N, Wang W, Xu W, Li Y, Liu H., Free PMC Article

    04/18/2022
    Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease.

    Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease.
    Li Z, Du Y, Jia L, Fan J, Guo R, Ma X, Wang X, Nie S, Wei Y., Free PMC Article

    04/18/2022
    Association of serum CTRP9 levels with cardiac autonomic neuropathy in patients with type 2 diabetes mellitus.

    Association of serum CTRP9 levels with cardiac autonomic neuropathy in patients with type 2 diabetes mellitus.
    Yang J, Zhao D, Chen Y, Ma Y, Shi X, Wang X, Lv Y, Yuan H., Free PMC Article

    01/1/2022
    Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training.

    Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training.
    Jerobin J, Ramanjaneya M, Bettahi I, Parammal R, Siveen KS, Alkasem M, Aye M, Sathyapalan T, Skarulis M, Atkin SL, Abou-Samra AB., Free PMC Article

    11/13/2021
    C1q/TNF-related protein-9 is elevated in hypertension and associated with the occurrence of hypertension-related atherogenesis.

    C1q/TNF-related protein-9 is elevated in hypertension and associated with the occurrence of hypertension-related atherogenesis.
    Zhou Q, Cheng W, Wang Z, Liu J, Han J, Wen S, Liu J.

    11/13/2021
    CTRP9: An emerging potential anti-aging molecule in brain.

    CTRP9: An emerging potential anti-aging molecule in brain.
    Rezabakhsh A, Sadeghpour Y, Ghaderi S, Rahbarghazi R, Geranmayeh MH.

    10/9/2021
    C1q/TNF-related protein-9 attenuates palmitic acid-induced endothelial cell senescence via increasing autophagy.

    C1q/TNF-related protein-9 attenuates palmitic acid-induced endothelial cell senescence via increasing autophagy.
    Lee J, Yoo JH, Kim HS, Cho YK, Lee Y, Lee WJ, Park JY, Jung CH.

    08/21/2021
    C1q/TNF-related Protein 9 Inhibits High Glucose-Induced Oxidative Stress and Apoptosis in Retinal Pigment Epithelial Cells Through the Activation of AMPK/Nrf2 Signaling Pathway.

    C1q/TNF-related Protein 9 Inhibits High Glucose-Induced Oxidative Stress and Apoptosis in Retinal Pigment Epithelial Cells Through the Activation of AMPK/Nrf2 Signaling Pathway.
    Cheng Y, Qi Y, Liu S, Di R, Shi Q, Li J, Pei C., Free PMC Article

    08/14/2021
    Protein-9 (CTRP9) levels associated with C1q tumor necrosis factor in obese preeclamptic, non-obese preeclamptic, obese and normal pregnant women.

    Protein-9 (CTRP9) levels associated with C1q tumor necrosis factor in obese preeclamptic, non-obese preeclamptic, obese and normal pregnant women.
    Aksin Ş, Andan C.

    07/3/2021
    Role of First-Trimester Serum C1q/TNF-Related Protein 9 in Gestational Diabetes Mellitus.

    Role of First-Trimester Serum C1q/TNF-Related Protein 9 in Gestational Diabetes Mellitus.
    Na N, Ji M.

    05/29/2021
    [Association between serum CTRP9 levels and diabetic retinopathy in patients with type 2 diabetes mellitus].

    [Association between serum CTRP9 levels and diabetic retinopathy in patients with type 2 diabetes mellitus].
    Zhou P, Liu L, Gao W., Free PMC Article

    04/17/2021
    CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response.

    CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response.
    Niemann B, Li L, Siegler D, Siegler BH, Knapp F, Hanna J, Aslam M, Kracht M, Schulz R, Rohrbach S., Free PMC Article

    02/27/2021
    The serum selenium level is negatively correlated with CAD. The polymorphism of the CYP4F2 rs3093135 and CTRP9 rs9553238 was significantly related to the susceptibility of CAD, and there is a synergistic effect between the serum selenium level and the CTRP9 rs9553238 CC genotype, which significantly increases the risk of CAD.

    Association of CYP4F2 and CTRP9 polymorphisms and serum selenium levels with coronary artery disease.
    Huang H, Wang Y, Wang X, Lei Y.

    06/27/2020
    Our data here demonstrated that the CTRP9 showed atheroprotective function and could down-regulate the expression of NLRP3 protein and also the activity of NLRP3 inflammasome in ox-LDL activated macrophages.

    C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway.
    Zhang H, Gong X, Ni S, Wang Y, Zhu L, Ji N.

    04/25/2020
    CTRP3 and CTRP9 are decreased in patients with heart failure with reduced ejection fraction, proportionate to disease severity, and each is associated with increased morbidity and mortality.

    C1q/TNF-related protein 3 (CTRP3) and 9 (CTRP9) concentrations are decreased in patients with heart failure and are associated with increased morbidity and mortality.
    Gao C, Zhao S, Lian K, Mi B, Si R, Tan Z, Fu F, Wang S, Wang R, Ma X, Tao L., Free PMC Article

    03/21/2020
    Serum CTRP9 is not independently related to NAFLD.

    Serum C1q/TNF-related protein 9 is not related to nonalcoholic fatty liver disease.
    Zhang C, Zhou N, Qiu P, Fu Y, Liu Z, Li H, Yang X, Zhang L.

    10/26/2019
    Study findings indicate a potential role for serum level of MCP-1 in combination with CTRP3 and CTRP9 as a diagnostic and prognostic tool in type 2 diabetes (T2D) and coronary artery disease as a complication of T2D in Egyptian postmenopausal female patients. Negative correlation between MCP-1 and CTRP9 proposes that the anti-inflammatory action of CTRP9 results from reducing MCP-1 production.

    Role of CTRP3, CTRP9 and MCP-1 for the evaluation of T2DM associated coronary artery disease in Egyptian postmenopausal females.
    Ahmed SF, Shabayek MI, Abdel Ghany ME, El-Hefnawy MH, El-Mesallamy HO., Free PMC Article

    06/8/2019
    A single bout of high-intensity interval exercise may stimulate CTRP1 and CTRP9 secretions in healthy men.

    Effects of a single bout of high-intensity interval exercise on C1q/TNF-related proteins.
    Kon M, Ebi Y, Nakagaki K.

    04/27/2019
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