| Upregulation of IFNE in cervical biopsies of patients with high-risk human papillomavirus infections. | Upregulation of IFNE in cervical biopsies of patients with high-risk human papillomavirus infections.
Zhang L, Zhou Y, Xing X, Li H, Zhang Z, Qian R, Hu X., Free PMC Article | 01/3/2024 |
| Interferon-epsilon is a tumour suppressor and restricts ovarian cancer. | Interferon-ε is a tumour suppressor and restricts ovarian cancer.
Marks ZRC, Campbell NK, Mangan NE, Vandenberg CJ, Gearing LJ, Matthews AY, Gould JA, Tate MD, Wray-McCann G, Ying L, Rosli S, Brockwell N, Parker BS, Lim SS, Bilandzic M, Christie EL, Stephens AN, de Geus E, Wakefield MJ, Ho GY, McNally O, Australian Ovarian Cancer Study, McNeish IA, Bowtell DDL, de Weerd NA, Scott CL, Bourke NM, Hertzog PJ. | 09/13/2023 |
| Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection. | Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection.
Coldbeck-Shackley RC, Romeo O, Rosli S, Gearing LJ, Gould JA, Lim SS, Van der Hoek KH, Eyre NS, Shue B, Robertson SA, Best SM, Tate MD, Hertzog PJ, Beard MR., Free PMC Article | 03/31/2023 |
| Spatiotemporal regulation of human IFN-epsilon and innate immunity in the female reproductive tract. | Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract.
Bourke NM, Achilles SL, Huang SU, Cumming HE, Lim SS, Papageorgiou I, Gearing LJ, Chapman R, Thakore S, Mangan NE, Mesiano S, Hertzog PJ., Free PMC Article | 10/8/2022 |
| average vaginal IFNe across pregnancy was lower in women with genital herpes simplex virus compared to healthy women | Interferon epsilon in the reproductive tract of healthy and genital herpes simplex virus-infected pregnant women: Results of a pilot study.
Nickodem C, Criscitiello MF, Bazer F, Abiodun-Ojo O, Taylor BD. | 11/2/2019 |
| IFN epsilon protects macrophages against HIV infection through a type I IFN independent mechanism. | IFN-ε protects primary macrophages against HIV infection.
Tasker C, Subbian S, Gao P, Couret J, Levine C, Ghanny S, Soteropoulos P, Zhao X, Landau N, Lu W, Chang TL., Free PMC Article | 05/21/2018 |
| human IFNvarepsilon suppresses HIV replication at multiple stages of infection. | Interferon epsilon promotes HIV restriction at multiple steps of viral replication.
Garcia-Minambres A, Eid SG, Mangan NE, Pade C, Lim SS, Matthews AY, de Weerd NA, Hertzog PJ, Mak J. | 03/3/2018 |
| female sex workers decreased susceptibility to HIV-1 infection also have increased levels of IFNE gene and protein expression in the cervical epithelium | HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes.
Abdulhaqq SA, Zorrilla C, Kang G, Yin X, Tamayo V, Seaton KE, Joseph J, Garced S, Tomaras GD, Linn KA, Foulkes AS, Azzoni L, VerMilyea M, Coutifaris C, Kossenkov AV, Showe L, Kraiselburd EN, Li Q, Montaner LJ., Free PMC Article | 11/4/2017 |
| T Allele of nonsense polymorphism (rs2039381, Gln71Stop) of interferon-epsilon is a risk factor for the development of intracerebral hemorrhage. | T Allele of nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε is a risk factor for the development of intracerebral hemorrhage.
Kim SK, Park HJ, Kim JW, Chung JH, Yoo SD, Kim DH, Yun DH, Kim HS. | 08/9/2014 |
| Full-length IFN-epsilon 5'UTR markedly suppressed mRNA expression under basal conditions. It contains 2 stable stem-loop structures which associate with importin 9. Loop 1 is essential for regulation of mRNA expression. | Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.
Matsumiya T, Xing F, Ebina M, Hayakari R, Imaizumi T, Yoshida H, Kikuchi H, Topham MK, Satoh K, Stafforini DM., Free PMC Article | 03/22/2014 |
| genetic polymorphism is related to onset time of vitiligo in Korean patients | Association study between nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε and susceptibility to vitiligo in Korean population.
Cho HR, Kim SK, Lim HK, Jeong Park H, Chung JH, Lee MH. | 02/15/2014 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesBivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study.
Melton PE, Rutherford S, Voruganti VS, Göring HH, Laston S, Haack K, Comuzzie AG, Dyer TD, Johnson MP, Kent JW Jr, Curran JE, Moses EK, Blangero J, Barac A, Lee ET, Best LG, Fabsitz RR, Devereux RB, Okin PM, Bella JN, Broeckel U, Howard BV, MacCluer JW, Cole SA, Almasy L. Dengue hemorrhagic fever is associated with polymorphisms in JAK1.
Silva LK, Blanton RE, Parrado AR, Melo PS, Morato VG, Reis EA, Dias JP, Castro JM, Vasconcelos PF, Goddard KA, Barreto ML, Reis MG, Teixeira MG. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.
Yang XR, Liang X, Pfeiffer RM, Wheeler W, Maeder D, Burdette L, Yeager M, Chanock S, Tucker MA, Goldstein AM. | 09/15/2010 |
| In macrophages IFN-tau increased the synthesis of 2',5'-oligoadenylate synthetase/RNase L, MxA protein, IL-10 & IL-6, but not of IL-1ss or TNF-alpha. | [Anti-HIV effects of IFN-tau in human macrophages: role of cellular antiviral factors and interleukin-6].
Maneglier B, Rogez-Kreuz C, Dereuddre-Bosquet N, Martal J, Devillier P, Dormont D, Clayette P. | 01/21/2010 |
| A meta-analysis and a single-nucleotide polymorphism (SNP) rs1333049 representing the 9p21.3 locus provide unprecedented evidence for association between genetic variants at chromosome 9p21.3 and risk of coronary artery disease. | Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.
Schunkert H, Götz A, Braund P, McGinnis R, Tregouet DA, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJ, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, König IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ, Cardiogenics Consortium., Free PMC Article | 01/21/2010 |
| TNF-alpha leads to stabilization of IFN-epsilon mRNA, increased IFN-epsilon synthesis, engagement of type I IFNRs, increased STAT1 expression and phosphorylation, and up-regulation of retinoic acid-inducible gene-I expression | IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells.
Matsumiya T, Prescott SM, Stafforini DM. | 01/21/2010 |
| The structue and mRNA expression pattern of IFN-epsilon1 suggest that it may have a function distinct from those other members of type I INF. | Characterization of the type I interferon locus and identification of novel genes.
Hardy MP, Owczarek CM, Jermiin LS, Ejdebäck M, Hertzog PJ. | 01/21/2010 |