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    HSPD1 heat shock protein family D (Hsp60) member 1 [ Homo sapiens (human) ]

    Gene ID: 3329, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Purification of functional recombinant human mitochondrial Hsp60.

    Purification of functional recombinant human mitochondrial Hsp60.
    Weiss C, Berruezo AG, Seraidy S, Parnas A, Tascón I, Ubarretxena-Belandia I, Azem A.

    11/7/2024
    HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis.

    HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis.
    Cömert C, Kjær-Sørensen K, Hansen J, Carlsen J, Just J, Meaney BF, Østergaard E, Luo Y, Oxvig C, Schmidt-Laursen L, Palmfeldt J, Fernandez-Guerra P, Bross P., Free PMC Article

    09/24/2024
    Quantitative analysis of the lysine acetylome reveals the role of SIRT3-mediated HSP60 deacetylation in suppressing intracellular Mycobacterium tuberculosis survival.

    Quantitative analysis of the lysine acetylome reveals the role of SIRT3-mediated HSP60 deacetylation in suppressing intracellular Mycobacterium tuberculosis survival.
    Zhu C, Duan Y, Dong J, Jia H, Zhang L, Xing A, Li Z, Du B, Sun Q, Huang Y, Zhang Z, Pan L., Free PMC Article

    08/9/2024
    Knockdown of heat shock protein family D member 1 (HSPD1) in lung cancer cell altered secretome profile and cancer-associated fibroblast induction.

    Knockdown of heat shock protein family D member 1 (HSPD1) in lung cancer cell altered secretome profile and cancer-associated fibroblast induction.
    Aluksanasuwan S, Somsuan K, Ngoenkam J, Chiangjong W, Rongjumnong A, Morchang A, Chutipongtanate S, Pongcharoen S.

    06/5/2024
    Potential association of HSPD1 with dysregulations in ribosome biogenesis and immune cell infiltration in lung adenocarcinoma: An integrated bioinformatic approach.

    Potential association of HSPD1 with dysregulations in ribosome biogenesis and immune cell infiltration in lung adenocarcinoma: An integrated bioinformatic approach.
    Aluksanasuwan S, Somsuan K, Ngoenkam J, Chutipongtanate S, Pongcharoen S., Free PMC Article

    04/5/2024
    Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).

    Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).
    Duan Y, Yu J, Chen M, Lu Q, Ning F, Gan X, Liu H, Ye Y, Lu S, Lash GE., Free PMC Article

    05/4/2023
    Human Mitochondrial Protein HSPD1 Binds to and Regulates the Repair of Deoxyinosine in DNA.

    Human Mitochondrial Protein HSPD1 Binds to and Regulates the Repair of Deoxyinosine in DNA.
    Zheng X, Chang S, Liu Y, Dai X, You C.

    04/10/2023
    Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma.

    Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma.
    Jiang R, Sun Y, Li Y, Tang X, Hui B, Ma S, Zhang J, Sun C, Tan J, Zhou B, Lei J, Jiang T.

    04/6/2023
    Chaperonin counteracts diet-induced non-alcoholic fatty liver disease by aiding sirtuin 3 in the control of fatty acid oxidation.

    Chaperonin counteracts diet-induced non-alcoholic fatty liver disease by aiding sirtuin 3 in the control of fatty acid oxidation.
    Weng SW, Wu JC, Shen FC, Chang YH, Su YJ, Lian WS, Tai MH, Su CH, Chuang JH, Lin TK, Liou CW, Chu TH, Kao YH, Wang FS, Wang PW.

    03/29/2023
    Reactivity to neural tissue epitopes, aquaporin 4 and heat shock protein 60 is associated with activated immune-inflammatory pathways and the onset of delirium following hip fracture surgery.

    Reactivity to neural tissue epitopes, aquaporin 4 and heat shock protein 60 is associated with activated immune-inflammatory pathways and the onset of delirium following hip fracture surgery.
    Maes M, Thisayakorn P, Thipakorn Y, Tantavisut S, Sirivichayakul S, Vojdani A.

    02/28/2023
    Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma.

    Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma.
    De Bakshi D, Chen YC, Wuerzberger-Davis SM, Ma M, Waters BJ, Li L, Suzuki A, Miyamoto S., Free PMC Article

    01/14/2023
    Hereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperonin.

    Hereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperonin.
    Chen L, Syed A, Balaji A., Free PMC Article

    11/5/2022
    Role of heat shock protein 60 in primed and naive states of human pluripotent stem cells.

    Role of heat shock protein 60 in primed and naïve states of human pluripotent stem cells.
    Choi HS, Lee HM, Kim MK, Ryu CJ., Free PMC Article

    06/18/2022
    Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-kappaB survival machinery in cancer cells.

    Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-κB survival machinery in cancer cells.
    Min S, Kim JY, Cho HM, Park S, Hwang JM, You H, Chan Chae Y, Lee WJ, Sun W, Kang D, Lee S, Kang SW., Free PMC Article

    04/23/2022
    HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.

    HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.
    Sun B, Li G, Yu Q, Liu D, Tang X.

    04/9/2022
    HSP60, SP110 and TNF-alpha expression in Chlamydia pneumoniae-positive versus Chlamydia pneumoniae-negative atherosclerotic plaques.

    HSP60, SP110 and TNF-α expression in Chlamydia pneumoniae-positive versus Chlamydia pneumoniae-negative atherosclerotic plaques.
    Radojevic N, Vukcevic B, Jovovic A, Vukmirovic F.

    03/26/2022
    Physiological and Genetically Engineered Expression Modulation Methods Do Not Affect Cellular Levels of the Heat Shock Protein HSP60 in Prostate Cancer Cells.

    Physiological and Genetically Engineered Expression Modulation Methods Do Not Affect Cellular Levels of the Heat Shock Protein HSP60 in Prostate Cancer Cells.
    Erb HHH, Streitbörger A, Mustea A, Stope MB., Free PMC Article

    03/12/2022
    Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity.

    Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity.
    Houzelle A, Jörgensen JA, Schaart G, Daemen S, van Polanen N, Fealy CE, Hesselink MKC, Schrauwen P, Hoeks J., Free PMC Article

    01/22/2022
    Hsp27 and Hsp60 in human submandibular salivary gland: Quantitative patterns in healthy and cancerous tissues with potential implications for differential diagnosis and carcinogenesis.

    Hsp27 and Hsp60 in human submandibular salivary gland: Quantitative patterns in healthy and cancerous tissues with potential implications for differential diagnosis and carcinogenesis.
    Basset CA, Rappa F, Lentini VL, Barone R, Pitruzzella A, Unti E, Cappello F, Conway de Macario E, Macario AJL, Leone A.

    01/15/2022
    Dilated cardiomyopathy-linked heat shock protein family D member 1 mutations cause up-regulation of reactive oxygen species and autophagy through mitochondrial dysfunction.

    Dilated cardiomyopathy-linked heat shock protein family D member 1 mutations cause up-regulation of reactive oxygen species and autophagy through mitochondrial dysfunction.
    Enomoto H, Mittal N, Inomata T, Arimura T, Izumi T, Kimura A, Fukuda K, Makino S.

    01/8/2022
    Visualization of Sparsely-populated Lower-order Oligomeric States of Human Mitochondrial Hsp60 by Cryo-electron Microscopy.

    Visualization of Sparsely-populated Lower-order Oligomeric States of Human Mitochondrial Hsp60 by Cryo-electron Microscopy.
    Wälti MA, Canagarajah B, Schwieters CD, Clore GM., Free PMC Article

    01/1/2022
    Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.

    Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.
    Wang JC, Chen L., Free PMC Article

    11/13/2021
    Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.

    Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.
    Tang Y, Yang Y, Luo J, Liu S, Zhan Y, Zang H, Zheng H, Zhang Y, Feng J, Fan S, Wen Q., Free PMC Article

    10/23/2021
    Overexpression and extra-mitochondrial localization of the chaperonin Hsp60 in ameloblastoma.

    Overexpression and extra-mitochondrial localization of the chaperonin Hsp60 in ameloblastoma.
    Rodríguez-Vázquez M, Muñiz-Lino MA, Shibayama M, Cruz-Tapia RO, Portilla-Robertson J, Ortiz-García JZ, Martínez-Ricardez AL, Licéaga-Escalera C, Rodríguez MA.

    10/9/2021
    HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation.

    HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation.
    Shirsath K, Joshi A, Vohra A, Devkar R., Free PMC Article

    08/21/2021
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