Protein Misfolding Releases Human HSF1 from HSP70 Latency Control. | Protein Misfolding Releases Human HSF1 from HSP70 Latency Control. Ciccarelli M, Andréasson C. | 09/23/2024 |
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment. | Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment. Liu Z, Lin Z, Jiang M, Zhu G, Xiong T, Cao F, Cui Y, Niu YN. | 08/23/2024 |
Intermolecular Interactions between Cysteine and Aromatic Amino Acids with a Phenyl Moiety in the DNA-Binding Domain of Heat Shock Factor 1 Regulate Thermal Stress-Induced Trimerization. | Intermolecular Interactions between Cysteine and Aromatic Amino Acids with a Phenyl Moiety in the DNA-Binding Domain of Heat Shock Factor 1 Regulate Thermal Stress-Induced Trimerization. Lee CJ, Choi BH, Kim SS, Kim DN, Kim TH, Choi JM, Pak Y, Park JS. | 07/25/2024 |
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. | Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro. Selvarajan I, Kiema M, Huang RT, Li J, Zhu J, Pölönen P, Örd T, Õunap K, Godiwala M, Golebiewski AK, Ravindran A, Mäklin K, Toropainen A, Stolze LK, Arce M, Magnusson PU, White S, Romanoski CE, Heinäniemi M, Laakkonen JP, Fang Y, Kaikkonen MU., | 05/29/2024 |
Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2. | Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2. Joutsen J, Pessa JC, Jokelainen O, Sironen R, Hartikainen JM, Sistonen L., Free PMC Article | 05/2/2024 |
Cellular HSF1 expression is induced during HIV-1 infection by activation of its promoter mediated through the cooperative interaction of HSF1 and viral Nef protein. | Cellular HSF1 expression is induced during HIV-1 infection by activation of its promoter mediated through the cooperative interaction of HSF1 and viral Nef protein. Mitra A, Dasgupta A, Mitra D. | 04/4/2024 |
ER Stress-Activated HSF1 Governs Cancer Cell Resistance to USP7 Inhibitor-Based Chemotherapy through the PERK Pathway. | ER Stress-Activated HSF1 Governs Cancer Cell Resistance to USP7 Inhibitor-Based Chemotherapy through the PERK Pathway. Lim CH, Fang XQ, Kang H, Oh T, Lee S, Kim YS, Lim JH., Free PMC Article | 03/14/2024 |
Novel mechanism of drug resistance triggered by tumor-associated macrophages through Heat Shock Factor-1 activation. | Novel mechanism of drug resistance triggered by tumor-associated macrophages through Heat Shock Factor-1 activation. Nikotina AD, Vladimirova SA, Kokoreva NE, Nevdakha VA, Lazarev VF, Kuznetcova LS, Komarova EY, Suezov RV, Efremov S, Leonova E, Kartsev VG, Aksenov ND, Margulis BA, Guzhova IV., Free PMC Article | 02/4/2024 |
Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation. | Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation. Tanaka N, Okada H, Yamaguchi K, Seki M, Matsubara D, Gotoh N, Suzuki Y, Furukawa Y, Yamashita T, Inoue JI, Kaneko S, Sakamoto T., Free PMC Article | 12/20/2023 |
HSF1 protects cells from cadmium toxicity by governing proteome integrity. | HSF1 protects cells from cadmium toxicity by governing proteome integrity. Zhang Y, Liang R, Chen Y, Wang Y, Li X, Wang S, Jin H, Liu L, Tang Z. | 11/28/2023 |
Silencing of heat shock factor 1 (HSF1) inhibits proliferation, invasion, and epithelial-mesenchymal transition in oral squamous cell carcinoma. | Silencing of heat shock factor 1 (HSF1) inhibits proliferation, invasion, and epithelial-mesenchymal transition in oral squamous cell carcinoma. da Silva LAB, da Costa LM, Massetti ACP, de Lucena Pereira L, da Silveira EJD, Salo TA, Coletta RD, da Costa Miguel MC. | 11/18/2023 |
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation. | Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation. Majumder S, Chattopadhyay A, Wright JM, Guan P, Buja LM, Kwartler CS, Milewicz DM., Free PMC Article | 11/14/2023 |
HSF-1 enhances cardioprotective potential of stem cells via exosome biogenesis and their miRNA cargo enrichment. | HSF-1 enhances cardioprotective potential of stem cells via exosome biogenesis and their miRNA cargo enrichment. Guru SA, Saha P, Chen L, Tulshyan A, Ge ZD, Baily J, Simons L, Stefanowicz A, Bilewska A, Mehta V, Mishra R, Sharma S, Ali A, Krishnan S, Kaushal S. | 11/3/2023 |
Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response. | Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response. Xu M, Lin L, Ram BM, Shriwas O, Chuang KH, Dai S, Su KH, Tang Z, Dai C., Free PMC Article | 10/11/2023 |
Human herpesvirus 6A nuclear matrix protein U37 interacts with heat shock transcription factor 1 and activates the heat shock response. | Human herpesvirus 6A nuclear matrix protein U37 interacts with heat shock transcription factor 1 and activates the heat shock response. Huang JR, Arii J, Hirai M, Nishimura M, Mori Y., Free PMC Article | 10/5/2023 |
MicroRNA-455-3p inhibits osteosarcoma progression via HSF1 downregulation. | MicroRNA-455-3p inhibits osteosarcoma progression via HSF1 downregulation. Wang C, Zhang D, Wang L, Wang W. | 09/12/2023 |
Repression motif in HSF1 regulated by phosphorylation. | Repression motif in HSF1 regulated by phosphorylation. Gabriel S, Czerny T, Riegel E. | 09/6/2023 |
HSF1 expression in tumor-associated macrophages promotes tumor cell proliferation and indicates poor prognosis in esophageal squamous cell carcinoma. | HSF1 expression in tumor-associated macrophages promotes tumor cell proliferation and indicates poor prognosis in esophageal squamous cell carcinoma. Li Y, Li Q, Liu J, Huang Y, Mao J, Zhang G. | 05/24/2023 |
Heat shock factor 1 is a promising therapeutic target against adult T-cell leukemia. | Heat shock factor 1 is a promising therapeutic target against adult T-cell leukemia. Ishikawa C, Mori N. | 05/17/2023 |
Crosstalk between heat shock factor 1 and signal transducer and activator of transcription 3 mediated by interleukin-8 autocrine signaling maintains the cancer stem cell phenotype in liver cancer. | Crosstalk between heat shock factor 1 and signal transducer and activator of transcription 3 mediated by interleukin-8 autocrine signaling maintains the cancer stem cell phenotype in liver cancer. Yang Z, Wan W, Zhang P, Wang S, Zhao Z, Xue J, Yao M, Zhao Y, Zheng W, Niu B, Wang M, Li H, Guo W, Ren Z, Hu Y. | 02/15/2023 |
Dual inhibition of HSF1 and DYRK2 impedes cancer progression. | Dual inhibition of HSF1 and DYRK2 impedes cancer progression. Tandon V, Moreno R, Allmeroth K, Quinn J, Wiley SE, Nicely LG, Denzel MS, Edwards J, de la Vega L, Banerjee S., Free PMC Article | 02/4/2023 |
HSF1 is involved in immunotherapeutic response through regulating APOJ/STAT3-mediated PD-L1 expression in hepatocellular carcinoma. | HSF1 is involved in immunotherapeutic response through regulating APOJ/STAT3-mediated PD-L1 expression in hepatocellular carcinoma. Cheng H, Wang S, Huang A, Ma J, Gao D, Li M, Chen H, Guo K., Free PMC Article | 12/31/2022 |
HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia. | HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia. Dong Q, Xiu Y, Wang Y, Hodgson C, Borcherding N, Jordan C, Buchanan J, Taylor E, Wagner B, Leidinger M, Holman C, Thiele DJ, O'Brien S, Xue HH, Zhao J, Li Q, Meyerson H, Boyce BF, Zhao C., Free PMC Article | 10/22/2022 |
Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer. | Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer. Pariollaud M, Ibrahim LH, Irizarry E, Mello RM, Chan AB, Altman BJ, Shaw RJ, Bollong MJ, Wiseman RL, Lamia KA., Free PMC Article | 10/8/2022 |
HSF1 Protects Sepsis-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome Activation. | HSF1 Protects Sepsis-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome Activation. Shi X, Li T, Liu Y, Yin L, Xiao L, Fu L, Zhu Y, Chen H, Wang K, Xiao X, Zhang H, Tan S, Tan S., Free PMC Article | 07/2/2022 |