| [Mechanism of HOXC6 promoting the progression of prostate cancer by activating the SFRP1/Wnt/beta-catenin signaling pathway]. | [Mechanism of HOXC6 promoting the progression of prostate cancer by activating the SFRP1/Wnt/β-catenin signaling pathway].
Zheng YJ, Li WM, Zheng LC, Zhou YF, Wang J, Xia WM, Ye WJ, Yu JS. | 10/9/2024 |
| High expression of HOXC6 predicts a poor prognosis and induces proliferation and inflammation in multiple myeloma cells. | High expression of HOXC6 predicts a poor prognosis and induces proliferation and inflammation in multiple myeloma cells.
Li Z, Wang Y, Hou X, Guo L, Li Y, Ma Y, Ma Y. | 06/25/2023 |
| LINC01857 promotes the proliferation, migration, and invasion of gastric cancer cells via regulating miR-4731-5p/HOXC6. | LINC01857 promotes the proliferation, migration, and invasion of gastric cancer cells via regulating miR-4731-5p/HOXC6.
Chen S, Dai J, Wang W, Ren C. | 09/3/2022 |
| HOXC6/8/10/13 predict poor prognosis and associate with immune infiltrations in glioblastoma. | HOXC6/8/10/13 predict poor prognosis and associate with immune infiltrations in glioblastoma.
Yu M, Yu S, Zhou W, Yi B, Liu Y. | 03/19/2022 |
| The Effects of Differentially-Expressed Homeobox Family Genes on the Prognosis and HOXC6 on Immune Microenvironment Orchestration in Colorectal Cancer. | The Effects of Differentially-Expressed Homeobox Family Genes on the Prognosis and HOXC6 on Immune Microenvironment Orchestration in Colorectal Cancer.
Qi L, Ye C, Zhang D, Bai R, Zheng S, Hu W, Yuan Y., Free PMC Article | 02/19/2022 |
| HOXC6-Mediated miR-188-5p Expression Induces Cell Migration through the Inhibition of the Tumor Suppressor FOXN2. | HOXC6-Mediated miR-188-5p Expression Induces Cell Migration through the Inhibition of the Tumor Suppressor FOXN2.
Jeong S, Kim SA, Ahn SG., Free PMC Article | 02/5/2022 |
| TrkB/C-induced HOXC6 activation enhances the ADAM8-mediated metastasis of chemoresistant colon cancer cells. | TrkB/C-induced HOXC6 activation enhances the ADAM8-mediated metastasis of chemoresistant colon cancer cells.
Park GB, Choi S, Yoon YS, Kim D. | 10/23/2021 |
| Prospective assessment of two-gene urinary test with multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy. | Prospective assessment of two-gene urinary test with multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy.
Busetto GM, Del Giudice F, Maggi M, De Marco F, Porreca A, Sperduti I, Magliocca FM, Salciccia S, Chung BI, De Berardinis E, Sciarra A., Free PMC Article | 10/2/2021 |
| HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/beta-catenin axis in right-sided colon cancer. | HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/β-catenin axis in right-sided colon cancer.
Qi L, Chen J, Zhou B, Xu K, Wang K, Fang Z, Shao Y, Yuan Y, Zheng S, Hu W., Free PMC Article | 09/18/2021 |
| HomeoboxC6 affects the apoptosis of human vascular endothelial cells and is involved in atherosclerosis. | HomeoboxC6 affects the apoptosis of human vascular endothelial cells and is involved in atherosclerosis.
Long X, You G, Wu Q, Zhou Y, Xiao Y, Yu F, Deng S, Mo R, Song F, Huang J, Tian M. | 09/18/2021 |
| MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-beta signaling pathway. | MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-β signaling pathway.
You X, Zhou Z, Chen W, Wei X, Zhou H, Luo W., Free PMC Article | 07/31/2021 |
| HoxC6 Functions as an Oncogene and Isoform HoxC6-2 May Play the Primary Role in Gastric Carcinogenesis. | HoxC6 Functions as an Oncogene and Isoform HoxC6-2 May Play the Primary Role in Gastric Carcinogenesis.
Lin J, He J, He X, Wang L, Xue M, Zhuo W, Si J, Wang K, Chen S. | 01/2/2021 |
| BBOX1 antisense RNA 1 facilitates CC progression by upregulating HOXC6 expression via miR-361-3p and HuR. | LncRNA BBOX1-AS1 upregulates HOXC6 expression through miR-361-3p and HuR to drive cervical cancer progression.
Xu J, Yang B, Wang L, Zhu Y, Zhu X, Xia Z, Zhao Z, Xu L., Free PMC Article | 08/12/2020 |
| These results illuminated that the novel Linc00339/miR-377-3p/HOXC6 axis played a critical role in triple-negative breast cancer (TNBC) progression and might be a promising therapeutic target for TNBC treatment. | Long noncoding RNA Linc00339 promotes triple-negative breast cancer progression through miR-377-3p/HOXC6 signaling pathway.
Wang X, Chen T, Zhang Y, Zhang N, Li C, Li Y, Liu Y, Zhang H, Zhao W, Chen B, Wang L, Yang Q. | 05/23/2020 |
| HOXC6 up-regulates BCL2 expression and promotes cervical cancer progression. | HOXC6 promotes cervical cancer progression via regulation of Bcl-2.
Wang Y, Wang C, Liu N, Hou J, Xiao W, Wang H. | 05/9/2020 |
| Up-regulated HOXC6, in PCa patients, could not only participate in the progression of PCa but also function as an independent prognostic marker for the cancer | HOXC6 in the prognosis of prostate cancer.
Zhou J, Yang X, Song P, Wang H, Wang X. | 12/14/2019 |
| HOXC6 may promote tumor progression by inducing epithelial-mesenchymal transition pathway and predicts poor prognosis of hepatocellular carcinoma. | HOXC6 predicts invasion and poor survival in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
Li PD, Chen P, Peng X, Ma C, Zhang WJ, Dai XF., Free PMC Article | 09/14/2019 |
| Urinary HOXC6 mRNA levels were quantified and RNA results were then combined with other risk factors in a clinical model optimized to detect International Society of Urological Pathology Grade Group 2 or greater prostate cancer in men with prostate specific antigen less than 10 ng/ml. | Multicenter Optimization and Validation of a 2-Gene mRNA Urine Test for Detection of Clinically Significant Prostate Cancer before Initial Prostate Biopsy.
Haese A, Trooskens G, Steyaert S, Hessels D, Brawer M, Vlaeminck-Guillem V, Ruffion A, Tilki D, Schalken J, Groskopf J, Van Criekinge W. | 08/17/2019 |
| our findings indicate that HOXC6 plays an important role in the progress and prognosis of human glioma and promotes glioma U87 cell growth through the WIF-1/Wnt signaling pathway | Knockdown of HOXC6 inhibits glioma cell proliferation and induces cell cycle arrest by targeting WIF-1 in vitro and vivo.
Yan TF, Wu MJ, Xiao B, Hu Q, Fan YH, Zhu XG. | 12/22/2018 |
| HOXC6 mRNA levels were shown to be good predictors for the detection of High-grade Prostate Cancer. | Detection of High-grade Prostate Cancer Using a Urinary Molecular Biomarker-Based Risk Score.
Van Neste L, Hendriks RJ, Dijkstra S, Trooskens G, Cornel EB, Jannink SA, de Jong H, Hessels D, Smit FP, Melchers WJ, Leyten GH, de Reijke TM, Vergunst H, Kil P, Knipscheer BC, Hulsbergen-van de Kaa CA, Mulders PF, van Oort IM, Van Criekinge W, Schalken JA. | 01/20/2018 |
| HOXC6 thus appears to promote colorectal cancer cell proliferation and tumorigenesis through autophagy inhibition | Silencing homeobox C6 inhibits colorectal cancer cell proliferation.
Ji M, Feng Q, He G, Yang L, Tang W, Lao X, Zhu D, Lin Q, Xu P, Wei Y, Xu J., Free PMC Article | 01/13/2018 |
| Increased expression of HOXC6 in gastric cancer cell lines significantly activated extracellular signalregulated kinase signaling and upregulated MMP9. The HOXC6 gene promotes the proliferation of gastric cancer cells while upregulation of MMP9 promotes migration and invasion of gastric cancer cells. | HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9.
Chen SW, Zhang Q, Xu ZF, Wang HP, Shi Y, Xu F, Zhang WJ, Wang P, Li Y. | 04/15/2017 |
| oxidized low-density lipoprotein (Ox-LDL) decreased expression of HOXC-AS1 and HOXC6 in a time-dependent manner | Long Noncoding RNA HOXC-AS1 Suppresses Ox-LDL-Induced Cholesterol Accumulation Through Promoting HOXC6 Expression in THP-1 Macrophages.
Huang C, Hu YW, Zhao JJ, Ma X, Zhang Y, Guo FX, Kang CM, Lu JB, Xiu JC, Sha YH, Gao JJ, Wang YC, Li P, Xu BM, Zheng L, Wang Q. | 02/18/2017 |
| HOXC6 has a role in all prostate cancer stages, particularly in prostate cancer cell proliferation. | The role of HOXC6 in prostate cancer development.
Hamid AR, Hoogland AM, Smit F, Jannink S, van Rijt-van de Westerlo C, Jansen CF, van Leenders GJ, Verhaegh GW, Schalken JA. | 02/6/2016 |
| Data demonstrate significant downregulation of HOXC6 in serous ovarian cancer and low protein level is associated with high-grade tumors. | Downregulation of HOXC6 in Serous Ovarian Cancer.
Tait DL, Bahrani-Mostafavi Z, Vestal CG, Richardson C, Mostafavi MT. | 11/14/2015 |