| Hsa-microRNA-1249-3p/Homeobox A13 axis modulates the expression of beta-catenin gene in human epithelial cells. | Hsa-microRNA-1249-3p/Homeobox A13 axis modulates the expression of β-catenin gene in human epithelial cells.
Mazziotta C, Iaquinta MR, Tramarin ML, Badiale G, Cervellera CF, Tonnini G, Patergnani S, Pinton P, Lanza G, Gafà R, Tognon M, Martini F, De Mattei M, Rotondo JC., Free PMC Article | 01/3/2024 |
| HOXA13 promotes the proliferation, migration, and invasion of nasopharyngeal carcinoma HNE1 cells by upregulating the expression of Snail and MMP-2. | HOXA13 promotes the proliferation, migration, and invasion of nasopharyngeal carcinoma HNE1 cells by upregulating the expression of Snail and MMP-2.
Liu J, Feng H, Wang D, Wang Y, Luo J, Xu S, Zhao F, Qin G., Free PMC Article | 08/16/2023 |
| Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma. | Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma.
Feng H, Zhao F, Luo J, Xu S, Liang Z, Xu W, Bao Y, Qin G., Free PMC Article | 08/3/2023 |
| Conclusion of diagnostic odysseys due to inversions disrupting GLI3 and FBN1. | Conclusion of diagnostic odysseys due to inversions disrupting GLI3 and FBN1.
Pagnamenta AT, Yu J, Evans J, Twiss P, Genomics England Research Consortium, Musculoskeletal GeCIP MDT, Offiah AC, Wafik M, Mehta SG, Javaid MK, Smithson SF, Taylor JC., Free PMC Article | 04/26/2023 |
| Hand-foot-genital syndrome due to a duplication variant in the GC-rich region of HOXA13. | Hand-foot-genital syndrome due to a duplication variant in the GC-rich region of HOXA13.
Geng W, Li F, Zhang R, Cao L, Du X, Gu W, Xu M. | 02/14/2023 |
| Circ_0008726 promotes malignant progression of ESCC cells through miR-206/HOXA13 pathway. | Circ_0008726 promotes malignant progression of ESCC cells through miR-206/HOXA13 pathway.
Han T, Shi M, Chen G, Hao J. | 01/21/2023 |
| Identification of a Novel circ_0010235/miR-1249-3p/HOXA13 Axis in Lung Adenocarcinoma. | Identification of a Novel circ_0010235/miR-1249-3p/HOXA13 Axis in Lung Adenocarcinoma.
Liu J, Fu Z. | 09/24/2022 |
| MiR-369-5p inhibits the proliferation and migration of hepatocellular carcinoma cells by down-regulating HOXA13 expression. | MiR-369-5p inhibits the proliferation and migration of hepatocellular carcinoma cells by down-regulating HOXA13 expression.
Qian X, Wang Y, Hu W, Xu X, Gao L, Meng Y, Yan J. | 03/26/2022 |
| Homeobox-A13 acts as a functional prognostic and diagnostic biomarker via regulating P53 and Wnt signaling pathways in lung cancer. | Homeobox-A13 acts as a functional prognostic and diagnostic biomarker via regulating P53 and Wnt signaling pathways in lung cancer.
Wang Y, He B, Dong Y, He GJ, Qi XW, Li Y, Yang YF, Rao Y, Cen ZS, Han F, Ding J, Li JJ. | 12/25/2021 |
| IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R. | IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R.
Qiao C, Huang W, Chen J, Feng W, Zhang T, Wang Y, Liu D, Ji X, Xie M, Sun M, Fan D, Wu K, Xia L., Free PMC Article | 10/16/2021 |
| Long non-coding RNA UCA1 mediates proliferation and metastasis of laryngeal squamous cell carcinoma cells via regulating miR-185-5p/HOXA13 axis. | Long non-coding RNA UCA1 mediates proliferation and metastasis of laryngeal squamous cell carcinoma cells via regulating miR-185-5p/HOXA13 axis.
Sun YD, Liu Q, Yang HX, Tian L, Wang J, Zeng L, Zhou XW. | 09/18/2021 |
| 3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia. | 3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia.
Yang L, Chen F, Zhu H, Chen Y, Dong B, Shi M, Wang W, Jiang Q, Zhang L, Huang X, Zhang MQ, Wu H., Free PMC Article | 07/10/2021 |
| HOXA13 in etiology and oncogenic potential of Barrett's esophagus. | HOXA13 in etiology and oncogenic potential of Barrett's esophagus.
Janmaat VT, Nesteruk K, Spaander MCW, Verhaar AP, Yu B, Silva RA, Phillips WA, Magierowski M, van de Winkel A, Stadler HS, Sandoval-Guzmán T, van der Laan LJW, Kuipers EJ, Smits R, Bruno MJ, Fuhler GM, Clemons NJ, Peppelenbosch MP., Free PMC Article | 07/3/2021 |
| HOXA13 promotes colon cancer progression through beta-catenin-dependent WNT pathway. | HOXA13 promotes colon cancer progression through β-catenin-dependent WNT pathway.
Gu Y, Gu J, Shen K, Zhou H, Hao J, Li F, Yu H, Chen Y, Li J, Li Y, Liang H, Dong Y. | 03/6/2021 |
| Forced expression of HOXA13 confers oncogenic hallmarks to esophageal keratinocytes. | Forced expression of HOXA13 confers oncogenic hallmarks to esophageal keratinocytes.
Nesteruk K, Janmaat VT, Liu H, Ten Hagen TLM, Peppelenbosch MP, Fuhler GM. | 01/9/2021 |
| Downregulated long noncoding RNA LUCAT1 inhibited proliferation and promoted apoptosis of cardiomyocyte via miR-612/HOXA13 pathway in chronic heart failure. | Downregulated long noncoding RNA LUCAT1 inhibited proliferation and promoted apoptosis of cardiomyocyte via miR-612/HOXA13 pathway in chronic heart failure.
Li T, Qian D, Guoyan J, Lei Z. | 01/2/2021 |
| Serum exosomal microRNA-766-3p expression is associated with poor prognosis of esophageal squamous cell carcinoma. | Serum exosomal microRNA-766-3p expression is associated with poor prognosis of esophageal squamous cell carcinoma.
Liu S, Lin Z, Zheng Z, Rao W, Lin Y, Chen H, Xie Q, Chen Y, Hu Z., Free PMC Article | 12/19/2020 |
| Knockdown of HOXA13 significantly suppressed cell proliferation of KIRC in vitro, increased the protein level of p53 and decreased the protein level of cyclin D1 in KIRC cells. Over-expression of HOXA13 had the opposite effects on KIRC cells. | Comprehensive analysis of the HOXA gene family identifies HOXA13 as a novel oncogenic gene in kidney renal clear cell carcinoma.
Cui Y, Yan M, Zhang C, Xue J, Zhang Q, Ma S, Guan F, Cao W. | 07/18/2020 |
| Our data also reveal a specific role for Hoxa13 in the urogenital sinus, which is in part mediated by Gata3, as well as Hoxa13 requirement for the proper organization of the ureter. Finally, we provide evidence that Hoxa13 provides positional and temporal cues during the development of the lower urogenital system, a sine qua non condition for the proper function of the urinary system. | Multifaceted Hoxa13 function in urogenital development underlies the Hand-Foot-Genital Syndrome.
Roux M, Bouchard M, Kmita M. | 02/8/2020 |
| Significant decrease in the expression of the genes HOXA13 and COL3A in the uterosacral ligaments in advanced stages of prolapse, indicates that these gene expressions may play a role in the development of uterine prolapse. | Expressions of homeobox, collagen and estrogen genes in women with uterine prolapse.
Dökmeci F, Tekşen F, Çetinkaya ŞE, Özkan T, Kaplan F, Köse K. | 06/1/2019 |
| Homeobox A13 (HOXA13) played a role of carcinogenesis through directly down-regulating dehydrogenase/reductase 2 (DHRS2) to increase proto-oncogene proteins c-mdm2 (MDM2). | HOXA13 contributes to gastric carcinogenesis through DHRS2 interacting with MDM2 and confers 5-FU resistance by a p53-dependent pathway.
Han Y, Song C, Wang J, Tang H, Peng Z, Lu S. | 03/2/2019 |
| High HOXA13 expression was associated with inferior tumor regression grade and poor overall survival in esophageal squamous cell carcinoma (ESCC) patients treated with neoadjuvant chemotherapy. HOXA13 increased cisplatin-resistance and promoted epithelial-to-mesenchymal transition in ESCC cells. | Downregulation of HOXA13 sensitizes human esophageal squamous cell carcinoma to chemotherapy.
Shi Q, Shen L, Dong B, Fu H, Kang X, Dai L, Yang Y, Yan W, Chen KN., Free PMC Article | 02/16/2019 |
| Data suggest that patients with HOXA13-positive hepatocellular carcinomas experience worse overall survival than those with HOXA13-negative HCC; HOXA13 and HOTTIP (know regulator of HOXA13 expression) are expressed in the same neoplastic hepatocyte populations. (HOTTIP = long noncoding RNA HOTTIP) | High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models.
Quagliata L, Quintavalle C, Lanzafame M, Matter MS, Novello C, di Tommaso L, Pressiani T, Rimassa L, Tornillo L, Roncalli M, Cillo C, Pallante P, Piscuoglio S, Ng CK, Terracciano LM. | 12/22/2018 |
| prognostic value of HOXA13 in solid tumors | The prognostic value of HOXA13 in solid tumors: A meta-analysis.
Wen Y, Shu F, Chen Y, Chen Y, Lan Y, Duan X, Zhao SC, Zeng G. | 10/6/2018 |
| HOXA13 is an unfavorable prognostic factor and a novel oncogene for prostate cancer. | HOXA13 is associated with unfavorable survival and acts as a novel oncogene in prostate carcinoma.
Dong Y, Cai Y, Liu B, Jiao X, Li ZT, Guo DY, Li XW, Wang YJ, Yang DK. | 08/11/2018 |