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    HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 [ Homo sapiens (human) ]

    Gene ID: 3178, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Dominant stop-loss HNRNPA1 variants in juvenile-onset myopathy.

    Dominant stop-loss HNRNPA1 variants in juvenile-onset myopathy.
    Turner J, Bruels CC, Daugherty AL, Estrella EA, Stafki S, Syeda SB, Littel HR, Pais L, Ganesh VS, Lidov HGW, Paine SML, Maddison P, Harrison RE, Straub V, Ghosh PS, Pacak CA, Kunkel LM, Draper I, Topf A, Kang PB.,

    10/22/2024
    Downregulation of HNRNPA1 induced neoantigen generation via regulating alternative splicing.

    Downregulation of HNRNPA1 induced neoantigen generation via regulating alternative splicing.
    Sun Y, Xiong B, Shuai X, Li J, Wang C, Guo J, Cheng Z, Liu S., Free PMC Article

    06/26/2024
    circLIFR-007 reduces liver metastasis via promoting hnRNPA1 nuclear export and YAP phosphorylation in breast cancer.

    circLIFR-007 reduces liver metastasis via promoting hnRNPA1 nuclear export and YAP phosphorylation in breast cancer.
    Zhang Y, Tan Y, Yuan J, Tang H, Zhang H, Tang Y, Xie Y, Wu L, Xie J, Xiao X, Li Y, Kong Y.

    06/8/2024
    A mutation in the low-complexity domain of splicing factor hnRNPA1 linked to amyotrophic lateral sclerosis disrupts distinct neuronal RNA splicing networks.

    A mutation in the low-complexity domain of splicing factor hnRNPA1 linked to amyotrophic lateral sclerosis disrupts distinct neuronal RNA splicing networks.
    Lee YJ, Rio DC., Free PMC Article

    02/20/2024
    MAGOH promotes gastric cancer progression via hnRNPA1 expression inhibition-mediated RONDelta160/PI3K/AKT signaling pathway activation.

    MAGOH promotes gastric cancer progression via hnRNPA1 expression inhibition-mediated RONΔ160/PI3K/AKT signaling pathway activation.
    Yu S, Chen C, Chen M, Liang J, Jiang K, Lou B, Lu J, Zhu X, Zhou D., Free PMC Article

    02/6/2024
    hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS).

    hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS).
    Salapa HE, Thibault PA, Libner CD, Ding Y, Clarke JWE, Denomy C, Hutchinson C, Abidullah HM, Austin Hammond S, Pastushok L, Vizeacoumar FS, Levin MC., Free PMC Article

    02/5/2024
    N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation.

    N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation.
    Xie R, Liu L, Lu X, He C, Yao H, Li G., Free PMC Article

    01/9/2024
    The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex.

    The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex.
    Ling X, Yao Y, Ding L, Ma J.

    11/20/2023
    HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.

    HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.
    Zhang Y, Huang J, Yan L, Jia R, Guo J.

    08/3/2023
    A comprehensive understanding of hnRNP A1 role in cancer: new perspectives on binding with noncoding RNA.

    A comprehensive understanding of hnRNP A1 role in cancer: new perspectives on binding with noncoding RNA.
    Siculella L, Giannotti L, Di Chiara Stanca B, Spedicato F, Calcagnile M, Quarta S, Massaro M, Damiano F.

    03/16/2023
    Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.

    Long noncoding RNA SNHG8 promotes chemoresistance in gastric cancer via binding with hnRNPA1 and stabilizing TROY expression.
    Zhu W, Tan L, Ma T, Yin Z, Gao J.

    11/5/2022
    Tumor-Promoting Actions of HNRNP A1 in HCC Are Associated with Cell Cycle, Mitochondrial Dynamics, and Necroptosis.

    Tumor-Promoting Actions of HNRNP A1 in HCC Are Associated with Cell Cycle, Mitochondrial Dynamics, and Necroptosis.
    Zhao B, Lv X, Zhao X, Maimaitiaili S, Zhang Y, Su K, Yu H, Liu C, Qiao T., Free PMC Article

    10/8/2022
    Expression of HnRNP A1, ZEB1, and E-cadherin in Hepatocellular carcinoma and their impact on patients' prognosis and survival.

    Expression of HnRNP A1, ZEB1, and E-cadherin in Hepatocellular carcinoma and their impact on patients' prognosis and survival.
    Abouhashem NS, Elwan A, El Hefnawy AS, Atwa HA.

    08/6/2022
    Protein Phosphatase 2A-Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping.

    Protein Phosphatase 2A-Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping.
    Sui JD, Tang Z, Chen BPC, Huang P, Yang MQ, Wang NH, Yang HN, Tu HL, Jiang QM, Zhang J, Wang Y, Wu YZ.

    08/6/2022
    Critical Role for Cap-Independent c-MYC Translation in Progression of Multiple Myeloma.

    Critical Role for Cap-Independent c-MYC Translation in Progression of Multiple Myeloma.
    Shi Y, Sun F, Cheng Y, Holmes B, Dhakal B, Gera JF, Janz S, Lichtenstein A., Free PMC Article

    07/9/2022
    hnRNP-A1 binds to the IRES of MELOE-1 antigen to promote MELOE-1 translation in stressed melanoma cells.

    hnRNP-A1 binds to the IRES of MELOE-1 antigen to promote MELOE-1 translation in stressed melanoma cells.
    Charpentier M, Dupré E, Fortun A, Briand F, Maillasson M, Com E, Pineau C, Labarrière N, Rabu C, Lang F., Free PMC Article

    07/9/2022
    Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication.

    Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication.
    Kaur R, Batra J, Stuchlik O, Reed MS, Pohl J, Sambhara S, Lal SK., Free PMC Article

    03/12/2022
    Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation.

    Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation.
    Beijer D, Kim HJ, Guo L, O'Donovan K, Mademan I, Deconinck T, Van Schil K, Fare CM, Drake LE, Ford AF, Kochański A, Kabzińska D, Dubuisson N, Van den Bergh P, Voermans NC, Lemmers RJ, van der Maarel SM, Bonner D, Sampson JB, Wheeler MT, Mehrabyan A, Palmer S, De Jonghe P, Shorter J, Taylor JP, Baets J., Free PMC Article

    02/26/2022
    Identification of an mRNA isoform switch for HNRNPA1 in breast cancers.

    Identification of an mRNA isoform switch for HNRNPA1 in breast cancers.
    Erdem M, Ozgul İ, Dioken DN, Gurcuoglu I, Guntekin Ergun S, Cetin-Atalay R, Can T, Erson-Bensan AE., Free PMC Article

    01/29/2022
    The role of frontotemporal dementia associated genes in patients with Alzheimer's disease.

    The role of frontotemporal dementia associated genes in patients with Alzheimer's disease.
    Xiao X, Yuan Z, Guo L, Liao X, Zhou Y, Zhang W, Zhou L, Wang X, Liu X, Liu H, Wang J, Li J, Shen L, Jiao B.

    01/29/2022
    Thermodynamic stability of hnRNP A1 low complexity domain revealed by high-pressure NMR.

    Thermodynamic stability of hnRNP A1 low complexity domain revealed by high-pressure NMR.
    Levengood JD, Peterson J, Tolbert BS, Roche J., Free PMC Article

    01/8/2022
    Electrostatic modulation of hnRNPA1 low-complexity domain liquid-liquid phase separation and aggregation.

    Electrostatic modulation of hnRNPA1 low-complexity domain liquid-liquid phase separation and aggregation.
    Tsoi PS, Quan MD, Choi KJ, Dao KM, Ferreon JC, Ferreon ACM., Free PMC Article

    12/25/2021
    Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells.

    Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells.
    Liao X, Zhan W, Li R, Tian T, Yu L, Yang Q.

    11/13/2021
    iTRAQ-based proteomic analysis of the molecular mechanisms and downstream effects of fatty acid synthase in osteosarcoma cells.

    iTRAQ-based proteomic analysis of the molecular mechanisms and downstream effects of fatty acid synthase in osteosarcoma cells.
    Fu D, Liu S, Liu J, Chen W, Long X, Chen X, Zhou Y, Zheng Y, Huang S., Free PMC Article

    11/6/2021
    RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing.

    RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing.
    Yan Q, Zeng P, Zhou X, Zhao X, Chen R, Qiao J, Feng L, Zhu Z, Zhang G, Chen C., Free PMC Article

    10/23/2021
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