TRIB3-TRIM8 complex drives NAFLD progression by regulating HNF4alpha stability. | TRIB3-TRIM8 complex drives NAFLD progression by regulating HNF4α stability. Xiao MC, Jiang N, Chen LL, Liu F, Liu SQ, Ding CH, Wu SH, Wang KQ, Luo YY, Peng Y, Yan FZ, Zhang X, Qian H, Xie WF. | 04/25/2024 |
Association between HNF4A rs1800961 polymorphisms and gallstones in a Taiwanese population. | Association between HNF4A rs1800961 polymorphisms and gallstones in a Taiwanese population. Lin YC, Chen IC, Chen YJ, Lin CT, Chang JC, Wang TJ, Chen YM, Lin CH. | 02/20/2024 |
Elucidating the Proximal Tubule HNF4A Gene Regulatory Network in Human Kidney Organoids. | Elucidating the Proximal Tubule HNF4A Gene Regulatory Network in Human Kidney Organoids. Yoshimura Y, Muto Y, Omachi K, Miner JH, Humphreys BD., | 02/8/2024 |
Insulin Determines Transforming Growth Factor beta Effects on Hepatocyte Nuclear Factor 4alpha Transcription in Hepatocytes. | Insulin Determines Transforming Growth Factor β Effects on Hepatocyte Nuclear Factor 4α Transcription in Hepatocytes. Feng R, Tong C, Lin T, Liu H, Shao C, Li Y, Sticht C, Kan K, Li X, Liu R, Wang S, Wang S, Munker S, Niess H, Meyer C, Liebe R, Ebert MP, Dooley S, Wang H, Ding H, Weng HL. | 01/6/2024 |
Ectopic expression of HNF4alpha in Het1A cells induces an invasive phenotype. | Ectopic expression of HNF4α in Het1A cells induces an invasive phenotype. Grimaldos Rodriguez C, Rimmer EF, Colleypriest B, Tosh D, Slack JMW, Jungwirth U. | 11/30/2023 |
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma. | The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma. Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M., Free PMC Article | 11/7/2023 |
HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer. | HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer. Zhou Q, Liu T, Qian W, Ji J, Cai Q, Jin Y, Jiang J, Zhang J., Free PMC Article | 10/20/2023 |
TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1. | TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1. Wang X, Shi J, Huang M, Chen J, Dan J, Tang Y, Guo Z, He X, Zhao Q., Free PMC Article | 08/9/2023 |
Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4alpha and Promotes Extrahepatic Carcinogenesis. | Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis. Goldman O, Adler LN, Hajaj E, Croese T, Darzi N, Galai S, Tishler H, Ariav Y, Lavie D, Fellus-Alyagor L, Oren R, Kuznetsov Y, David E, Jaschek R, Stossel C, Singer O, Malitsky S, Barak R, Seger R, Erez N, Amit I, Tanay A, Saada A, Golan T, Rubinek T, Sang Lee J, Ben-Shachar S, Wolf I, Erez A., Free PMC Article | 07/24/2023 |
High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy. | High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy. Yin Y, Wu S, Niu L, Huang S., Free PMC Article | 06/26/2023 |
HNF4alpha, SP1 and c-myc are master regulators of CNS autoimmunity. | HNF4α, SP1 and c-myc are master regulators of CNS autoimmunity. Colombo E, Di Dario M, Menon R, Valente MM, Bassani C, Sarno N, Mazza D, Montini F, Moiola L, Comi G, Martinelli V, Farina C. | 06/22/2023 |
Interleukin-1ss Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4alpha Independent of c-Jun. | Interleukin-1ß Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4α Independent of c-Jun. Nimphy J, Ibrahim S, Dayoub R, Kubitza M, Melter M, Weiss TS., Free PMC Article | 06/7/2023 |
Hepatocyte Nuclear Factor 4alpha (HNF4alpha) Plays a Controlling Role in Expression of the Retinoic Acid Receptor beta (RARbeta) Gene in Hepatocytes. | Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes. Zolfaghari R, Bonzo JA, Gonzalez FJ, Ross AC., Free PMC Article | 05/31/2023 |
Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase. | Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase. Besskaya V, Zhang H, Bian Y, Liang J, Bi G, Shan G, Zhan C, Lin Z., Free PMC Article | 05/23/2023 |
Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population. | Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population. Binjawhar DN, Ansari MGA, Sabico S, Hussain SD, Alenad AM, Alokail MS, Al-Masri AA, Al-Daghri NM., Free PMC Article | 04/14/2023 |
HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway. | HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway. Liang J, Zhao G, Bian Y, Bi G, Sui Q, Zhang H, Shi H, Shan G, Huang Y, Chen Z, Wang L, Zhan C., Free PMC Article | 03/21/2023 |
HNF4alpha overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure. | HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure. Yu Y, Zhang Q, Wu N, Xia L, Cao J, Xia Q, Zhao J, Zhang J, Hang H. | 03/5/2023 |
A transcriptional regulatory network of HNF4alpha and HNF1alpha involved in human diseases and drug metabolism. | A transcriptional regulatory network of HNF4α and HNF1α involved in human diseases and drug metabolism. Yang J, Bai X, Liu G, Li X. | 01/11/2023 |
Expression of p-STAT3 and c-Myc correlates with P2-HNF4alpha expression in nonalcoholic fatty liver disease (NAFLD). | Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD). Younes M, Zhang L, Fekry B, Eckel-Mahan K., Free PMC Article | 12/17/2022 |
Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis. | Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis. Argemi J, Kedia K, Gritsenko MA, Clemente-Sanchez A, Asghar A, Herranz JM, Liu ZX, Atkinson SR, Smith RD, Norden-Krichmar TM, Day LZ, Stolz A, Tayek JA, Bataller R, Morgan TR, Jacobs JM, Southern California Alcoholic Hepatitis Consortium and the InTeam Consortium., Free PMC Article | 12/10/2022 |
miR-3154 promotes hepatocellular carcinoma progression via suppressing HNF4alpha. | miR-3154 promotes hepatocellular carcinoma progression via suppressing HNF4α. Wei Y, Wei L, Han T, Ding S. | 12/3/2022 |
Hepatocyte nuclear factor 4alpha in the pathogenesis of non-alcoholic fatty liver disease. | Hepatocyte nuclear factor 4α in the pathogenesis of non-alcoholic fatty liver disease. Pan X, Zhang Y., Free PMC Article | 08/6/2022 |
Progressive loss of hepatocyte nuclear factor 4 alpha activity in chronic liver diseases in humans. | Progressive loss of hepatocyte nuclear factor 4 alpha activity in chronic liver diseases in humans. Gunewardena S, Huck I, Walesky C, Robarts D, Weinman S, Apte U., Free PMC Article | 07/23/2022 |
Clinical profiling and screening for HNF4alpha and GCK gene mutations in Kashmiri patients with maturity-onset diabetes of the young (MODY). | Clinical profiling and screening for HNF4α and GCK gene mutations in Kashmiri patients with maturity-onset diabetes of the young (MODY). Firdous P, Hassan T, Nissar K, Masoodi SR, Ganai BA. | 05/21/2022 |
Comparison of Different Hepatocyte Nuclear Factor 4alpha Clones for Invasive Mucinous Adenocarcinoma of the Lung. | Comparison of Different Hepatocyte Nuclear Factor 4α Clones for Invasive Mucinous Adenocarcinoma of the Lung. Hsia Y, Huang HC, Chang WC. | 05/14/2022 |