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    HMGB3 high mobility group box 3 [ Homo sapiens (human) ]

    Gene ID: 3149, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ELAVL1 regulates glycolysis in nasopharyngeal carcinoma cells through the HMGB3/beta-catenin axis.

    ELAVL1 regulates glycolysis in nasopharyngeal carcinoma cells through the HMGB3/β-catenin axis.
    Cui Y, Wen H, Tang J, Chen J, Zhou J, Hou M, Rong X, Lan Y, Wu Q., Free PMC Article

    10/18/2024
    HMGB3 and SUB1 Bind to and Facilitate the Repair of N[2]-Alkylguanine Lesions in DNA.

    HMGB3 and SUB1 Bind to and Facilitate the Repair of N(2)-Alkylguanine Lesions in DNA.
    Zhao T, He X, Liang X, Kellum AH Jr, Tang F, Yin J, Guo S, Wang Y, Gao Z, Wang Y.,

    08/15/2024
    Structure and Functions of HMGB3 Protein.

    Structure and Functions of HMGB3 Protein.
    Chikhirzhina E, Tsimokha A, Tomilin AN, Polyanichko A., Free PMC Article

    07/29/2024
    Exosomal HMGB3 released by glioma cells confers the activation of NLRP3 inflammasome and pyroptosis in tumor-associated macrophages.

    Exosomal HMGB3 released by glioma cells confers the activation of NLRP3 inflammasome and pyroptosis in tumor-associated macrophages.
    Hu P, Yan T, Lv S, Ye M, Wu M, Fang H, Xiao B.

    07/1/2024
    HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.

    HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
    Ma H, Qi G, Han F, Gai P, Peng J, Kong B., Free PMC Article

    06/23/2023
    Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/beta-Catenin Signal Pathway.

    Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/β-Catenin Signal Pathway.
    Gao S, Zhang X, Bai W, Wang J, Jiang B.

    05/30/2023
    SOX9 and HMGB3 co-operatively transactivate NANOG and promote prostate cancer progression.

    SOX9 and HMGB3 co-operatively transactivate NANOG and promote prostate cancer progression.
    Xu Y, Xu M, Li X, Weng X, Su Z, Zhang M, Tan J, Zeng H, Li X, Nie L, Gong J, Chen N, Chen X, Zhou Q.

    02/28/2023
    Long Noncoding RNA Brain Cytoplasmic RNA 1 Induces Cisplatin-Resistance of Cervical Cancer Cells by Sponging MicroRNA-330-5p and Upregulating High-Mobility Group Box 3.

    Long Noncoding RNA Brain Cytoplasmic RNA 1 Induces Cisplatin-Resistance of Cervical Cancer Cells by Sponging MicroRNA-330-5p and Upregulating High-Mobility Group Box 3.
    Sun D, Cao R, Han L, Yu X, Wang H, Wang X, Chen X.

    10/15/2022
    HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.

    HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
    Ma H, Qi G, Han F, Lu W, Peng J, Li R, Yan S, Yuan C, Kong B., Free PMC Article

    04/23/2022
    LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3.

    LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3.
    Yuan L, Tian X, Zhang Y, Huang X, Li Q, Li W, Li S., Free PMC Article

    03/26/2022
    miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells.

    miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells.
    Sharma P, Yadav P, Jain RP, Bera AK, Karunagaran D.

    02/19/2022
    LINC00857 promotes colorectal cancer progression by sponging miR-150-5p and upregulating HMGB3 (high mobility group box 3) expression.

    LINC00857 promotes colorectal cancer progression by sponging miR-150-5p and upregulating HMGB3 (high mobility group box 3) expression.
    Zhou D, He S, Zhang D, Lv Z, Yu J, Li Q, Li M, Guo W, Qi F., Free PMC Article

    02/19/2022
    High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/beta-catenin pathway.

    High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/β-catenin pathway.
    Zhuang S, Yu X, Lu M, Li Y, Ding N, Ding Y., Free PMC Article

    09/4/2021
    MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells.

    MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells.
    Gu M, Jiang Z, Li H, Peng J, Chen X, Tang M.

    09/4/2021
    CircRNA_102179 promotes the proliferation, migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis.

    CircRNA_102179 promotes the proliferation, migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis.
    Zhou ZF, Wei Z, Yao JC, Liu SY, Wang F, Wang Z, Chen XF, Lin H, Ye Y, Zheng QF.

    08/28/2021
    Long Noncoding RNA SOX2-OT Knockdown Inhibits Proliferation and Metastasis of Prostate Cancer Cells Through Modulating the miR-452-5p/HMGB3 Axis and Inactivating Wnt/beta-Catenin Pathway.

    Long Noncoding RNA SOX2-OT Knockdown Inhibits Proliferation and Metastasis of Prostate Cancer Cells Through Modulating the miR-452-5p/HMGB3 Axis and Inactivating Wnt/β-Catenin Pathway.
    Song X, Wang H, Wu J, Sun Y.

    07/17/2021
    The role of high mobility group protein B3 (HMGB3) in tumor proliferation and drug resistance.

    The role of high mobility group protein B3 (HMGB3) in tumor proliferation and drug resistance.
    Wen B, Wei YT, Zhao K.

    07/17/2021
    High-mobility group box 3 (HMGB3) silencing inhibits non-small cell lung cancer development through regulating Wnt/beta-catenin pathway.

    High-mobility group box 3 (HMGB3) silencing inhibits non-small cell lung cancer development through regulating Wnt/β-catenin pathway.
    Li Y, Ma Y, Zhang T, Feng C, Liu Y.

    06/26/2021
    LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA.

    LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA.
    Ren P, Xing L, Hong X, Chang L, Zhang H., Free PMC Article

    05/22/2021
    Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.

    Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
    Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H.

    02/6/2021
    Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis.

    Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis.
    Chen WL, Jiang L, Wang JS, Liao CX.

    12/19/2020
    HMGB3 small interfere RNA suppresses mammosphere formation of MDA-MB-231 cells by down-regulating expression of HIF1alpha.

    HMGB3 small interfere RNA suppresses mammosphere formation of MDA-MB-231 cells by down-regulating expression of HIF1α.
    Gu J, Xu T, Zhang CM, Chen HY, Huang QH, Zhang Q.

    12/19/2020
    LncRNA SNHG5 promotes nasopharyngeal carcinoma progression by regulating miR-1179/HMGB3 axis.

    LncRNA SNHG5 promotes nasopharyngeal carcinoma progression by regulating miR-1179/HMGB3 axis.
    Liu D, Wang Y, Zhao Y, Gu X., Free PMC Article

    10/24/2020
    High HMGB3 expression is associated with Chemo-resistance in Ovarian Cancer.

    Targeting the High-Mobility Group Box 3 Protein Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin.
    Mukherjee A, Huynh V, Gaines K, Reh WA, Vasquez KM., Free PMC Article

    04/11/2020
    HOTTIP was upregulated and miR-615-3p was downregulated in non-small cell lung cancer (NSCLC) tissues and cells. Hypoxia induced glycolysis, increased HOTTIP and HMGB3 mRNA levels and repressed miR-615-3p expression in NSCLC cells. HOTTIP deficiency or miR-615-3p expression restoration repressed hypoxia-induced glycolysis. HOTTIP acted as a molecular sponge for miR-615-3p and HMGB3 was a direct target of miR-615-3p.

    Long non-coding RNA HOTTIP promotes hypoxia-induced glycolysis through targeting miR-615-3p/HMGB3 axis in non-small cell lung cancer cells.
    Shi J, Wang H, Feng W, Huang S, An J, Qiu Y, Wu K.

    03/7/2020
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