| Secreted phospholipase PLA2G2E contributes to regulation of T cell immune response against influenza virus infection. | Secreted phospholipase PLA2G2E contributes to regulation of T cell immune response against influenza virus infection.
Bu H, Zhang S, Li P, Liu Z, Liu Y, Li Z, Liu X, Wang Z, Feng L, Chen L, Qu L., Free PMC Article | 06/5/2024 |
| PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke. | PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke.
Nakamura A, Sakai S, Taketomi Y, Tsuyama J, Miki Y, Hara Y, Arai N, Sugiura Y, Kawaji H, Murakami M, Shichita T. | 10/11/2023 |
| The atypical binding mechanism of second calcium on phospholipase A2 group IIE. | The atypical binding mechanism of second calcium on phospholipase A2 group IIE.
Hou S, Bai J, Chen C, Zhang X, Chang F, Cao Z, Xu T, Xie J. | 08/14/2021 |
| [Effect of E54 mutation of human secreted phospholipase A2 GIIE on substrate selectivity]. | [Effect of E54 mutation of human secreted phospholipase A2 GIIE on substrate selectivity].
Hou S, Bai J, Lu X, Zhang Y, Xu T, Xie J. | 08/7/2021 |
| Residue Asn21 acts as a switch for calcium binding to modulate the enzymatic activity of human phospholipase A2 group IIE. | Residue Asn21 acts as a switch for calcium binding to modulate the enzymatic activity of human phospholipase A2 group IIE.
Hou S, Zhang Y, Xu J, Bai J, Liu J, Xie J, Xu T. | 01/9/2021 |
| that are responsible for interacting with inhibitors, and illustrated the difference in the inhibitor binding pocket with other secretory phospholipase A2s. | Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A(2) group IIE.
Hou S, Xu T, Xu J, Qu L, Xu Y, Chen L, Liu J., Free PMC Article | 05/25/2019 |
| expression of PLA2s-IIE and -V correlates with the development of calcification as well as the expression of pro-osteogenic molecules in human aortic valves | The expression of groups IIE and V phospholipase A2 is associated with an increased expression of osteogenic molecules in human calcified aortic valves.
Suzuki K, Takahashi S, Watanabe K, Fujioka D, Nakamura T, Obata JE, Kawabata K, Katoh R, Matsumoto M, Kugiyama K. | 09/5/2015 |
| sPLA(2) -IIE regulates lipolysis in adipocytes, likely through the ERK/HSL signaling pathway | Group IIE secretory phospholipase A2 regulates lipolysis in adipocytes.
Zhi H, Qu L, Wu F, Chen L, Tao J. | 08/29/2015 |
| Single-nucleotide polymorphism in PLA2G2E gene is associated with ulcerative colitis. | Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians.
Yang SK, Hong M, Zhao W, Jung Y, Tayebi N, Ye BD, Kim KJ, Park SH, Lee I, Shin HD, Cheong HS, Kim LH, Kim HJ, Jung SA, Kang D, Youn HS, Liu J, Song K. | 09/28/2013 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.
Segat L, Brandão LAC, Guimarães RL, Pontillo A, Athanasakis E, de Oliveira RM, Arraes LC, de Lima Filho JL, Crovella S. | 06/30/2010 |
| promotes stimulus-induced arachidonic acid release and prostaglandin (PG) production similar to those elicited by HSPG-dependent sPLA(2)s, suggesting that this enzyme plays a role in the inflammatory process. | Arachidonate release and eicosanoid generation by group IIE phospholipase A(2).
Murakami M, Yoshihara K, Shimbara S, Lambeau G, Singer A, Gelb MH, Sawada M, Inagaki N, Nagai H, Kudo I. | 01/21/2010 |