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    CFH complement factor H [ Homo sapiens (human) ]

    Gene ID: 3075, updated on 17-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Protective role of complement factor H against the development of preeclampsia.

    Protective role of complement factor H against the development of preeclampsia.
    Yasmin H, Agostinis C, Toffoli M, Roy T, Pegoraro S, Balduit A, Zito G, Di Simone N, Ricci G, Madan T, Kishore U, Bulla R., Free PMC Article

    03/14/2024
    Gliosis-dependent expression of complement factor H truncated variants attenuates retinal neurodegeneration following ischemic injury.

    Gliosis-dependent expression of complement factor H truncated variants attenuates retinal neurodegeneration following ischemic injury.
    Biber J, Jabri Y, Glänzer S, Dort A, Hoffelner P, Schmidt CQ, Bludau O, Pauly D, Grosche A., Free PMC Article

    02/28/2024
    Association of KDR (rs2071559, rs1870377), CFH (rs1061170, rs1410996) genes variants and serum levels with pituitary adenoma.

    Association of KDR (rs2071559, rs1870377), CFH (rs1061170, rs1410996) genes variants and serum levels with pituitary adenoma.
    Bruzaite A, Gedvilaite G, Kriauciuniene L, Liutkeviciene R., Free PMC Article

    02/7/2024
    Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy.

    Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy.
    Kang Y, Xu B, Shi S, Zhou X, Chen P, Liu L, Li Y, Leng Y, Lv J, Zhu L, Zhang H.,

    12/21/2023
    Complement factor H attenuates TNF-alpha-induced inflammation by upregulating EIF3C in rheumatoid arthritis.

    Complement factor H attenuates TNF-α-induced inflammation by upregulating EIF3C in rheumatoid arthritis.
    Jia Y, Feng B, Ji X, Tian X, Zhao L, Zhou J, Zhang W, Li M, Fei Y, Wu X., Free PMC Article

    11/28/2023
    Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.

    Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.
    Lokki AI, Ren Z, Triebwasser M, Daly E, FINNPEC, Perola M, Auro K, Burwick R, Salmon JE, Daly M, Laivuori H, Atkinson JP, Java A, Meri S.,

    10/11/2023
    Reduced binding of apoE4 to complement factor H promotes amyloid-beta oligomerization and neuroinflammation.

    Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation.
    Chernyaeva L, Ratti G, Teirilä L, Fudo S, Rankka U, Pelkonen A, Korhonen P, Leskinen K, Keskitalo S, Salokas K, Gkolfinopoulou C, Crompton KE, Javanainen M, Happonen L, Varjosalo M, Malm T, Leinonen V, Chroni A, Saavalainen P, Meri S, Kajander T, Wollman AJ, Nissilä E, Haapasalo K., Free PMC Article

    07/12/2023
    CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.

    CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.
    Sugawara Y, Kato H, Nagasaki M, Yoshida Y, Fujisawa M, Minegishi N, Yamamoto M, Nangaku M., Free PMC Article

    05/30/2023
    Low level of complement factor H increases the risk of cancer-related death in patients with small-cell lung cancer.

    Low level of complement factor H increases the risk of cancer-related death in patients with small-cell lung cancer.
    Xiang M, Zhang H, Kou L, Chen J, Xu Z, He J.

    04/19/2023
    Rare germline complement factor H variants in patients with paroxysmal nocturnal hemoglobinuria.

    Rare germline complement factor H variants in patients with paroxysmal nocturnal hemoglobinuria.
    Prata PH, Galimard JE, Sicre de Fontbrune F, Duval A, Vieira Martins P, Roncelin S, Debureaux PÉ, Lepretre AC, Larcher L, Birsen R, Benhamou Y, Soulier J, Socié G, Fremeaux-Bacchi V, Peffault de Latour R.

    04/19/2023
    CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.

    CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.
    Piras R, Valoti E, Alberti M, Bresin E, Mele C, Breno M, Liguori L, Donadelli R, Rigoldi M, Benigni A, Remuzzi G, Noris M., Free PMC Article

    02/17/2023
    Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.

    Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.
    Fenner BJ, Li H, Gan ATL, Song YS, Tham YC, Jonas JB, Wang YX, Cheng CY, Wong TY, Teo KYC, Tan ACS, Fan Q, Cheung CMG., Free PMC Article

    02/13/2023
    A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.

    A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.
    Hallam TM, Cox TE, Smith-Jackson K, Brocklebank V, Baral AJ, Tzoumas N, Steel DH, Wong EKS, Shuttleworth VG, Lotery AJ, Harris CL, Marchbank KJ, Kavanagh D., Free PMC Article

    01/21/2023
    An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration.

    An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration.
    Biggs RM, Makou E, Lauder S, Herbert AP, Barlow PN, Katti SK., Free PMC Article

    12/3/2022
    Common complement factor H polymorphisms are linked with periodontitis in elderly patients.

    Common complement factor H polymorphisms are linked with periodontitis in elderly patients.
    Salminen A, Pietiäinen M, Paju S, Sorsa T, Mäntylä P, Buhlin K, Sinisalo J, Pussinen PJ., Free PMC Article

    12/3/2022
    Complement factor H variants are associated with microangiopathy lesions in IgA nephropathy.

    Complement factor H variants are associated with microangiopathy lesions in IgA nephropathy.
    Hou W, Shi S, Zhou X, Wang S, Cai Q, Chen P, Liu L, Zhu L, Lv J, Zhang H.

    10/29/2022
    Phenotypic Expression of CFH Rare Variants in Age-Related Macular Degeneration Patients in the Coimbra Eye Study.

    Phenotypic Expression of CFH Rare Variants in Age-Related Macular Degeneration Patients in the Coimbra Eye Study.
    Farinha C, Barreto P, Coimbra R, Iutis A, Cachulo ML, Cunha-Vaz J, Lechanteur YTE, Hoyng CB, Silva R., Free PMC Article

    10/22/2022
    Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis.

    Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis.
    Gouda HR, Talaat IM, Bouzid A, El-Assi H, Nabil A, Venkatachalam T, Manasa Bhamidimarri P, Wohlers I, Mahdami A, El-Gendi S, ElKoraie A, Busch H, Saber-Ayad M, Hamoudi R, Baddour N., Free PMC Article

    10/15/2022
    Role of CFH Y402H and ARMS2 A69S polymorphisms in susceptibility to post rhegmatogenous retinal detachment macular complications.

    Role of CFH Y402H and ARMS2 A69S polymorphisms in susceptibility to post rhegmatogenous retinal detachment macular complications.
    Aydinlou ZH, Vaezi H, Bonyadi M, Rafat A, Jabbarpoor Bonyadi MH, Soheilian M.

    09/17/2022
    Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish.

    Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish.
    Waksmunski AR, Miskimen K, Song YE, Grunin M, Laux R, Fuzzell D, Fuzzell S, Adams LD, Caywood L, Prough M, Stambolian D, Scott WK, Pericak-Vance MA, Haines JL., Free PMC Article

    08/13/2022
    Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis.

    Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis.
    van Beek AE, Pouw RB, Wright VJ, Sallah N, Inwald D, Hoggart C, Brouwer MC, Galassini R, Thomas J, Calvo-Bado L, Fink CG, Jongerius I, Hibberd M, Wouters D, Levin M, Kuijpers TW., Free PMC Article

    07/2/2022
    Genetic Variants of Complement Factor H Y402H (rs1061170), C2 R102G (rs2230199), and C3 E318D (rs9332739) and Response to Intravitreal Anti-VEGF Treatment in Patients with Exudative Age-Related Macular Degeneration.

    Genetic Variants of Complement Factor H Y402H (rs1061170), C2 R102G (rs2230199), and C3 E318D (rs9332739) and Response to Intravitreal Anti-VEGF Treatment in Patients with Exudative Age-Related Macular Degeneration.
    Kubicka-Trząska A, Żuber-Łaskawiec K, Dziedzina S, Sanak M, Romanowska-Dixon B, Karska-Basta I., Free PMC Article

    06/11/2022
    Systemic complement levels in patients with age-related macular degeneration carrying rare or low-frequency variants in the CFH gene.

    Systemic complement levels in patients with age-related macular degeneration carrying rare or low-frequency variants in the CFH gene.
    de Jong S, de Breuk A, Volokhina EB, Bakker B, Garanto A, Fauser S, Katti S, Hoyng CB, Lechanteur YTE, van den Heuvel LP, den Hollander AI., Free PMC Article

    05/7/2022
    Association of central serous chorioretinopathy with single nucleotide polymorphisms in complement factor H gene in Iranian population.

    Association of central serous chorioretinopathy with single nucleotide polymorphisms in complement factor H gene in Iranian population.
    Karkhaneh R, Toufighi M, Amirfiroozy A, Ahmad-Raji A, Ahmadzadeh O, Mahdavi A, Naderan M., Free PMC Article

    05/7/2022
    Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy.

    Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy.
    de Breuk A, Heesterbeek TJ, Bakker B, Verzijden T, Lechanteur YTE, Klaver CCW, den Hollander AI, Hoyng CB., Free PMC Article

    04/23/2022
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