| The m6A reader IGF2BP2 promotes ESCC progression by stabilizing HDGF mRNA. | The m6A reader IGF2BP2 promotes ESCC progression by stabilizing HDGF mRNA.
Jia Y, Liu S, Zhang M, Wu X, Chen X, Xing M, Hou X, Jiang W. | 09/11/2024 |
| Binding Behavior of Human Hepatoma-Derived Growth Factor on SMYD1. | Binding Behavior of Human Hepatoma-Derived Growth Factor on SMYD1.
Wu JK, Lee YY, Hung H, Chang YP, Tai MH, Fan HF., Free PMC Article | 08/21/2024 |
| [miR-29a-3p Targets Hepatoma-Derived Growth Factor to Inhibit the Proliferation and Promote the Apoptosis of E6-1 Cells]. | [miR-29a-3p Targets Hepatoma-Derived Growth Factor to Inhibit the Proliferation and Promote the Apoptosis of E6-1 Cells].
Zhou J, Huang CL, Liu HW, Zeng ZY, Tan J. | 12/17/2022 |
| Extracellular vesicle proteomic analysis leads to the discovery of HDGF as a new factor in multiple myeloma biology. | Extracellular vesicle proteomic analysis leads to the discovery of HDGF as a new factor in multiple myeloma biology.
Hoelzinger DB, Quinton SJ, Walters DK, Vardam-Kaur T, Tschumper RC, Borges da Silva H, Jelinek DF., Free PMC Article | 06/25/2022 |
| Specificity protein 1-induced serine peptidase inhibitor, Kunitz Type 1 antisense RNA1 regulates colorectal cancer cell proliferation, migration, invasion and apoptosis through targeting heparin binding growth factor via sponging microRNA-214. | Specificity protein 1-induced serine peptidase inhibitor, Kunitz Type 1 antisense RNA1 regulates colorectal cancer cell proliferation, migration, invasion and apoptosis through targeting heparin binding growth factor via sponging microRNA-214.
Fang Y, Yang Q., Free PMC Article | 02/26/2022 |
| miR-4323 targets hepatoma-derived growth factor (HDGF) to suppress colorectal cancer cell proliferation. | miR-4323 targets hepatoma-derived growth factor (HDGF) to suppress colorectal cancer cell proliferation.
Xia C, Li Q, Cheng X, Wu T, Gao P. | 02/5/2022 |
| Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis. | Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis.
Fazio M, van Rooijen E, Mito JK, Modhurima R, Weiskopf E, Yang S, Zon LI., Free PMC Article | 01/15/2022 |
| Exosomal lncRNA HEIH promotes cisplatin resistance in tongue squamous cell carcinoma via targeting miR-3619-5p/HDGF axis. | Exosomal lncRNA HEIH promotes cisplatin resistance in tongue squamous cell carcinoma via targeting miR-3619-5p/HDGF axis.
Wang X, Yu H, Yu Z, Wang D. | 09/4/2021 |
| A novel HDGF-ALCAM axis promotes the metastasis of Ewing sarcoma via regulating the GTPases signaling pathway. | A novel HDGF-ALCAM axis promotes the metastasis of Ewing sarcoma via regulating the GTPases signaling pathway.
Yang Y, Ma Y, Gao H, Peng T, Shi H, Tang Y, Li H, Chen L, Hu K, Han A. | 07/31/2021 |
| Long intergenic noncoding RNA LINC01232 contributes to esophageal squamous cell carcinoma progression by sequestering microRNA6543p and consequently promoting hepatomaderived growth factor expression. | Long intergenic non‑coding RNA LINC01232 contributes to esophageal squamous cell carcinoma progression by sequestering microRNA‑654‑3p and consequently promoting hepatoma‑derived growth factor expression.
Zhao M, Cui H, Zhao B, Li M, Man H., Free PMC Article | 07/10/2021 |
| Long noncoding RNA MKLN1AS aggravates hepatocellular carcinoma progression by functioning as a molecular sponge for miR6543p, thereby promoting hepatomaderived growth factor expression. | Long non‑coding RNA MKLN1‑AS aggravates hepatocellular carcinoma progression by functioning as a molecular sponge for miR‑654‑3p, thereby promoting hepatoma‑derived growth factor expression.
Gao W, Chen X, Chi W, Xue M., Free PMC Article | 07/3/2021 |
| Hsa_circ_0079480 promotes tumor progression in acute myeloid leukemia via miR-654-3p/HDGF axis. | Hsa_circ_0079480 promotes tumor progression in acute myeloid leukemia via miR-654-3p/HDGF axis.
Hu Q, Gu Y, Chen S, Tian Y, Yang S., Free PMC Article | 05/8/2021 |
| Hepatoma-Derived Growth Factor: An Overview and Its Role as a Potential Therapeutic Target Molecule for Digestive Malignancies. | Hepatoma-Derived Growth Factor: An Overview and Its Role as a Potential Therapeutic Target Molecule for Digestive Malignancies.
Enomoto H, Nakamura H, Nishikawa H, Nishiguchi S, Iijima H., Free PMC Article | 02/20/2021 |
| METTL3-mediated m(6)A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. | METTL3-mediated m(6)A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance.
Wang Q, Chen C, Ding Q, Zhao Y, Wang Z, Chen J, Jiang Z, Zhang Y, Xu G, Zhang J, Zhou J, Sun B, Zou X, Wang S. | 02/20/2021 |
| Prognostic Influence of Cytoplasmic/Nuclear Hepatoma-derived Growth Factor in Head and Neck Cancer. | Prognostic Influence of Cytoplasmic/Nuclear Hepatoma-derived Growth Factor in Head and Neck Cancer.
Lee HP, Tsai KW, Lee CC. | 02/6/2021 |
| Secreted HDGF contributes to the antiapoptosis of pancreatic stellate cells and consequently leads to the synthesis and deposition of extracellular matrix proteins for stabilizing PSC/pancreatic cancer cell tumor foci. | Hepatoma-derived growth factor supports the antiapoptosis and profibrosis of pancreatic stellate cells.
Chen YT, Chen FW, Chang TH, Wang TW, Hsu TP, Chi JY, Hsiao YW, Li CF, Wang JM. | 05/2/2020 |
| High HDGF expression is associated with oral cancer. | Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis.
Lin YW, Huang ST, Wu JC, Chu TH, Huang SC, Lee CC, Tai MH., Free PMC Article | 04/18/2020 |
| HDGF secretion by Helicobacter pylori (Hp) infection promotes the neutrophils infiltration and relays Hp-induced inflammatory signaling. Thus, HDGF may constitute a novel diagnostic marker and therapeutic target for Hp-induced gastritis and carcinogenesis. | Hepatoma-derived growth factor participates in Helicobacter Pylori-induced neutrophils recruitment, gastritis and gastric carcinogenesis.
Chu TH, Huang ST, Yang SF, Li CJ, Lin HW, Weng BC, Yang SM, Huang SC, Wu JC, Chang YC, Wen ZH, Chen YA, Wu WJ, Kung ML, Tai PH, Wu DC, Tai MH. | 02/1/2020 |
| HDGF acts as a coactivator of SREBP-1-mediated transcription of lipogenic genes. The coexpression of HDGF and SREBP-1 is positively correlated with poor prognosis in hepatocellular carcinoma patients. HDGF and SREBP-1 synergistically promote hepatocellular carcinoma development by activating lipid biosynthesis. The HDGF/SREBP-1 axis might be used to develop new diagnostic and therapeutic targets. | Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
Min X, Wen J, Zhao L, Wang K, Li Q, Huang G, Liu J, Zhao X., Free PMC Article | 08/24/2019 |
| AGAP2-AS1 promoted glioma cell proliferation by sponging miR-15a/b-5p to upregulate the expression of HDGF | Long non-coding RNA AGAP2-AS1 promotes the proliferation of glioma cells by sponging miR-15a/b-5p to upregulate the expression of HDGF and activating Wnt/β-catenin signaling pathway.
Zheng Y, Lu S, Xu Y, Zheng J. | 06/29/2019 |
| miR139 was downregulated in epithelial ovarian cancer, and acted as a tumor suppressor by directly targeting HDGF. | MicroRNA‑139 suppressed tumor cell proliferation, migration and invasion by directly targeting HDGF in epithelial ovarian cancer.
Liu J, Jin S, Wang R. | 04/21/2018 |
| high serum levels of HDGF were significantly correlated to bone metastasis and poorer prognosis of non-small cell lung cancer. | High Serum HDGF Levels Are Predictive of Bone Metastasis and Unfavorable Prognosis in Non-Small Cell Lung Cancer.
Zhang G, Liu Z, Chen Y, Zhang Y. | 03/31/2018 |
| Data suggested that HDGF knockdown inhibits cellular migration and invasion in vitro of prostate cancer via modulating epithelial-mesenchymal transition signaling pathway, as well as MMP2 and MMP9 signaling pathway. These results supported that HDGF is a relevant protein in the progression of prostate cancer and may serve as a potentially therapeutic target for prostate cancer as well as its downstream targets. | Downregulated expression of hepatoma-derived growth factor inhibits migration and invasion of prostate cancer cells by suppressing epithelial-mesenchymal transition and MMP2, MMP9.
Yang F, Yu N, Wang H, Zhang C, Zhang Z, Li Y, Li D, Yan L, Liu H, Xu Z., Free PMC Article | 02/3/2018 |
| HDGF is overexpressed in both androgen-sensitive and androgen-insensitive cell lines. Forced overexpression enhanced cell viability but knockdown reduced proliferation of benign prostate cells.Ectopic HDGF overexpression of HDGF in up-regulated cyclin E and BCL-2, but down-regulated BAX. Treatment with a HDGF monoclonal antibody and vitamin K2 reduced proliferation and inhibited NF-kB expression in a tumor cell line. | Hepatoma-derived growth factor: A survival-related protein in prostate oncogenesis and a potential target for vitamin K2.
Shetty A, Dasari S, Banerjee S, Gheewala T, Zheng G, Chen A, Kajdacsy-Balla A, Bosland MC, Munirathinam G., Free PMC Article | 01/20/2018 |
| functional diversity of HDGF isoforms | Intra- or extra-exosomal secretion of HDGF isoforms: the extraordinary function of the HDGF-A N-terminal peptide.
Nüße J, Blumrich EM, Mirastschijski U, Kappelmann L, Kelm S, Dietz F. | 07/22/2017 |