| Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction | Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction.
Janzen C, Lei MYY, Jeong ISD, Ganguly A, Sullivan P, Paharkova V, Capodanno G, Nakamura H, Perry A, Shin BC, Lee KW, Devaskar SU., Free PMC Article | 06/30/2018 |
| these data suggest that cytoplasmic trehalose access is carrier-mediated, and that GLUT8 is a mammalian trehalose transporter required for hepatocyte trehalose-induced autophagy and signal transduction. | SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.
Mayer AL, Higgins CB, Heitmeier MR, Kraft TE, Qian X, Crowley JR, Hyrc KL, Beatty WL, Yarasheski KE, Hruz PW, DeBosch BJ., Free PMC Article | 06/9/2018 |
| glucose/fructose is transported into the cytoplasm of vimentin- or GFAP-positive astrocytic and CD68- or HLA-DR-positive microglial cells located around the lateral ventricle | Glucose transporter 8 immunoreactivity in astrocytic and microglial cells in subependymal areas of human brains.
Mashima M, Chiba Y, Murakami R, Uemura N, Matsumoto K, Kawauchi M, Kanenishi K, Hata T, Ueno M. | 08/26/2017 |
| The findings support the hypothesis of the transport of intravascularGLUT8 through the epithelial cells of the choroid plexus and the ependymal cells. | Immunoreactivity of glucose transporter 8 is localized in the epithelial cells of the choroid plexus and in ependymal cells.
Murakami R, Chiba Y, Tsuboi K, Matsumoto K, Kawauchi M, Fujihara R, Mashima M, Kanenishi K, Yamamoto T, Ueno M. | 06/10/2017 |
| GLUT8 is thus essential for hepatocyte fructose transport and fructose-induced macrosteatosis. | Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis.
DeBosch BJ, Chen Z, Saben JL, Finck BN, Moley KH., Free PMC Article | 06/7/2014 |
| SLC2A8 is upregulated in fast progressing Alzheimer's disease patients, compared to slow progressors. | Gene expression profiling of peripheral blood leukocytes shows consistent longitudinal downregulation of TOMM40 and upregulation of KIR2DL5A, PLOD1, and SLC2A8 among fast progressors in early Alzheimer's disease.
Chong MS, Goh LK, Lim WS, Chan M, Tay L, Chen G, Feng L, Ng TP, Tan CH, Lee TS. | 11/2/2013 |
| Critical roles for novel GLUT family members highlight a therapeutic strategy entailing selective GLUT inhibition to specifically target aberrant glucose metabolism in cancer. | Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy.
McBrayer SK, Cheng JC, Singhal S, Krett NL, Rosen ST, Shanmugam M., Free PMC Article | 07/21/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. | 12/5/2010 |
| The expression pattern of GLUT8 is reported in newly diagnosed esophageal adenocarcinoma by means of immunohistochemistry. | Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.
Fonteyne P, Casneuf V, Pauwels P, Van Damme N, Peeters M, Dierckx R, Van de Wiele C. | 01/21/2010 |
| The recruitment of GLUT8 to the endocytic machinery occurs via direct interaction of the dileucine motif with beta2-adaptin, and that endocytosis might be the main site at which GLUT8 is likely to be regulated. | Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.
Schmidt U, Briese S, Leicht K, Schürmann A, Joost HG, Al-Hasani H. | 01/21/2010 |
| This carrier protein is expressed in human tissues of the testis in a gonadotropin-dependent manner. | The glucose transport facilitator GLUT8 is predominantly associated with the acrosomal region of mature spermatozoa.
Schürmann A, Axer H, Scheepers A, Doege H, Joost HG. | 01/21/2010 |