SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus. | SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus. Song CC, Liu T, Hogstrand C, Zhong CC, Zheng H, Sun LH, Luo Z., Free PMC Article | 10/7/2024 |
SENP1 knockdown potentiates the apoptosis, cell cycle arrest, and reduces cisplatin resistance of diffuse large B cell lymphoma cells via inducing ferroptosis. | SENP1 knockdown potentiates the apoptosis, cell cycle arrest, and reduces cisplatin resistance of diffuse large B cell lymphoma cells via inducing ferroptosis. Dong J, Zheng X. | 08/4/2024 |
N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2. | N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2. Wen D, Xiao H, Gao Y, Zeng H, Deng J., Free PMC Article | 06/7/2024 |
SENP1-Mediated deSUMOylation Regulates the Tumor Remodeling of Glioma Stem Cells Under Hypoxic Stress. | SENP1-Mediated deSUMOylation Regulates the Tumor Remodeling of Glioma Stem Cells Under Hypoxic Stress. Wen P, Li H, Liu L, Liu X, Xu Z, Dong J., Free PMC Article | 06/3/2024 |
METTL3-mediated m[6]A modification of lncRNA TSPAN12 promotes metastasis of hepatocellular carcinoma through SENP1-depentent deSUMOylation of EIF3I. | METTL3-mediated m(6)A modification of lncRNA TSPAN12 promotes metastasis of hepatocellular carcinoma through SENP1-depentent deSUMOylation of EIF3I. Li B, Xiong X, Xu J, Peng D, Nie G, Wen N, Wang Y, Lu J. | 04/2/2024 |
EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signallingdagger. | EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signalling†. Zhang H, Kong L, Cao Z, Zhu Y, Jiang Y, Wang X, Jiang R, Liu Y, Zhou J, Kang Y, Zhen X, Kong N, Wu M, Yan G, Sun H. | 03/18/2024 |
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1. | SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1. Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J., Free PMC Article | 01/12/2024 |
A role and mechanism for redox sensing by SENP1 in beta-cell responses to high fat feeding. | A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding. Lin H, Suzuki K, Smith N, Li X, Nalbach L, Fuentes S, Spigelman AF, Dai XQ, Bautista A, Ferdaoussi M, Aggarwal S, Pepper AR, Roma LP, Ampofo E, Li WH, MacDonald PE., Free PMC Article | 01/10/2024 |
SENP1-mediated SUMOylation of SIRT1 affects glioma development through the NF-kappaB pathway. | SENP1-mediated SUMOylation of SIRT1 affects glioma development through the NF-κB pathway. Liu X, Zhang S, Dong Y, Xie Y, Li Q. | 12/28/2023 |
SENP1 knockdown-mediated CTCF SUMOylation enhanced its stability and alleviated lipopolysaccharide-evoked inflammatory injury in human lung fibroblasts via regulation of FOXA2 transcription. | SENP1 knockdown-mediated CTCF SUMOylation enhanced its stability and alleviated lipopolysaccharide-evoked inflammatory injury in human lung fibroblasts via regulation of FOXA2 transcription. Kang L, Wang X, Wang J, Guo J, Zhang W, Lei R. | 12/21/2023 |
MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape. | MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape. Lemma RB, Ledsaak M, Fuglerud BM, Rodríguez-Castañeda F, Eskeland R, Gabrielsen OS., Free PMC Article | 10/4/2023 |
SENP1 Decreases RNF168 Phase Separation to Promote DNA Damage Repair and Drug Resistance in Colon Cancer. | SENP1 Decreases RNF168 Phase Separation to Promote DNA Damage Repair and Drug Resistance in Colon Cancer. Wei M, Huang X, Liao L, Tian Y, Zheng X. | 09/6/2023 |
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1alpha axis. | LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis. Sun W, Lei X, Lu Q, Wu Q, Ma Q, Huang D, Zhang Y. | 03/15/2023 |
SENP1-KLF4 signalling regulates LPS-induced macrophage M1 polarization. | SENP1-KLF4 signalling regulates LPS-induced macrophage M1 polarization. Wang K, Xiong J, Lu Y, Wang L, Tian T. | 01/14/2023 |
[SENP1 induced protein deSUMO modification increased the chemotherapy sensitivity of endometrial cancer side population cells]. | [SENP1 induced protein deSUMO modification increased the chemotherapy sensitivity of endometrial cancer side population cells]. Yuan ML, Bai J, Li CY, Xue N, Chen XH, Sheng F, Liu XZ, Li P. | 12/31/2022 |
Insights into the Allosteric Effect of SENP1 Q597A Mutation on the Hydrolytic Reaction of SUMO1 via an Integrated Computational Study. | Insights into the Allosteric Effect of SENP1 Q597A Mutation on the Hydrolytic Reaction of SUMO1 via an Integrated Computational Study. Ji M, Chai Z, Chen J, Li G, Li Q, Li M, Ding Y, Lu S, Ju G, Hou J., Free PMC Article | 07/23/2022 |
SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation. | SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation. Gao Y, Wang R, Liu J, Zhao K, Qian X, He X, Liu H., Free PMC Article | 04/30/2022 |
SENP1 participates in Irinotecan resistance in human colon cancer cells. | SENP1 participates in Irinotecan resistance in human colon cancer cells. Chen MC, Nhan DC, Hsu CH, Wang TF, Li CC, Ho TJ, Mahalakshmi B, Chen MC, Yang LY, Huang CY. | 02/19/2022 |
Circular RNA circ_0089153 acts as a competing endogenous RNA to regulate colorectal cancer development by the miR-198/SUMO-specific peptidase 1 (SENP1) axis. | Circular RNA circ_0089153 acts as a competing endogenous RNA to regulate colorectal cancer development by the miR-198/SUMO-specific peptidase 1 (SENP1) axis. Fang G, Chen T, Mao R, Huang X, Ji L., Free PMC Article | 01/1/2022 |
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway. | Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway. Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S. | 11/13/2021 |
SENP1 is required for the growth, migration, and survival of human adipose-derived stem cells. | SENP1 is required for the growth, migration, and survival of human adipose-derived stem cells. Wu Y, Yu B, Wang M., Free PMC Article | 10/9/2021 |
SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. | SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. Wang JQ, Lin ZC, Li LL, Zhang SF, Li WH, Liu W, Song BL, Luo J., Free PMC Article | 08/28/2021 |
Regulation of ALS-Associated SOD1 Mutant SUMOylation and Aggregation by SENP and PIAS Family Proteins. | Regulation of ALS-Associated SOD1 Mutant SUMOylation and Aggregation by SENP and PIAS Family Proteins. Wada H, Suzuki D, Niikura T. | 08/21/2021 |
Long noncoding RNA MCM3AP-AS1 enhances cell proliferation and metastasis in colorectal cancer by regulating miR-193a-5p/SENP1. | Long noncoding RNA MCM3AP-AS1 enhances cell proliferation and metastasis in colorectal cancer by regulating miR-193a-5p/SENP1. Zhou M, Bian Z, Liu B, Zhang Y, Cao Y, Cui K, Sun S, Li J, Zhang J, Wang X, Li C, Yao S, Yin Y, Fei B, Huang Z., Free PMC Article | 07/24/2021 |
SENP1/HIF-1alpha axis works in angiogenesis of human dental pulp stem cells. | SENP1/HIF-1α axis works in angiogenesis of human dental pulp stem cells. Zhou J, Sun C. | 10/10/2020 |