| SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance. | SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.
Vokshi BH, Davidson G, Tawanaie Pour Sedehi N, Helleux A, Rippinger M, Haller AR, Gantzer J, Thouvenin J, Baltzinger P, Bouarich R, Manriquez V, Zaidi S, Rao P, Msaouel P, Su X, Lang H, Tricard T, Lindner V, Surdez D, Kurtz JE, Bourdeaut F, Tannir NM, Davidson I, Malouf GG., Free PMC Article | 05/30/2023 |
| The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System. | The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System.
Sohn EJ, Nam YK. | 04/9/2022 |
| The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells. | The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells.
Zhang M, Ji J, Wang X, Zhang X, Zhang Y, Li Y, Wang X, Li X, Ban Q, Ye SD., Free PMC Article | 11/27/2021 |
| Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development. | Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development.
Hancock GV, Liu W, Peretz L, Chen D, Gell JJ, Collier AJ, Zamudio JR, Plath K, Clark AT., Free PMC Article | 10/30/2021 |
| Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis. | Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis.
Heo J, Noh BJ, Lee S, Lee HY, Kim Y, Lim J, Ju H, Yu HY, Ryu CM, Lee PC, Jeong H, Oh Y, Kim K, Kim SY, Son J, Hong B, Kim JS, Cho YM, Shin DM., Free PMC Article | 07/31/2021 |
| These findings indicate that TFCP2L1 functions differently in naive and primed pluripotency, insights that may help elucidate the different states of pluripotency. | The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.
Wang X, Wang X, Zhang S, Sun H, Li S, Ding H, You Y, Zhang X, Ye SD., Free PMC Article | 10/19/2019 |
| these findings reveal the unique and crucial role of Tfcp2l1 in the determination of human embryonic stem cell fate. | Tfcp2l1 safeguards the maintenance of human embryonic stem cell self-renewal.
Sun H, You Y, Guo M, Wang X, Zhang Y, Ye S. | 10/5/2019 |
| Studies reveal that TFCP2, TFCP2L1, UBP1 belong to a transcription factors subfamily and involved in various aspects of cancer types and development as either proto-oncogenes or tumor suppressors. They can directly interact with each other; TFCP2, TFCP2L1 and UBP1 can form heteromeric DNA-binding complexes. In addition, TFCP2L1 can modulate the activity of TFCP2 and UBP1. [review] | TFCP2/TFCP2L1/UBP1 transcription factors in cancer.
Kotarba G, Krzywinska E, Grabowska AI, Taracha A, Wilanowski T. | 03/23/2019 |
| Study show that CRTR-1 is generally an activator of transcription and that it modulates the activity of other family members, CP2, NF2d9 and altNF2d9, in a cell specific manner. | Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation.
To S, Rodda SJ, Rathjen PD, Keough RA., Free PMC Article | 10/30/2010 |
| LBP-1b and LBP-9 both stimulate LBP-32/MGR promoter activity. | LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation.
Henderson YC, Frederick MJ, Wang MT, Hollier LM, Clayman GL. | 01/21/2010 |
| LBP-1b is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of LBP-1b, exerting both positive and negative effects | LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.
Huang N, Miller WL. | 01/21/2010 |