| The relationship between miRNA-210 and SCN1B in fetal rats with hypoxic-ischemic brain injury. | The relationship between miRNA-210 and SCN1B in fetal rats with hypoxic-ischemic brain injury.
Al-Ward H, Liu N, Omorou M, Huang Y, Chen W, Liu CY, Lv S, Murshed A, Shaher F, Li Y, Zhang Y, Lu L, Gao W, Sun YE, Xu H., Free PMC Article | 01/28/2023 |
| Nav1.1 and Nav1.2 are highly expressed in axon terminals in central hilus compared to stratum radiatum and in dendrites and spines in stratum radiatum compared to central hilus | Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.
Johnson KW, Herold KF, Milner TA, Hemmings HC Jr, Platholi J., Free PMC Article | 05/26/2018 |
| the role of the intracellular IFM motif of rNav1.4 (skeletal muscle isoform of the rat Na(+) channel) on the alpha-beta1 functional interaction | Characterization of specific allosteric effects of the Na(+) channel β1 subunit on the Na(v)1.4 isoform.
Sánchez-Solano A, Islas AA, Scior T, Paiz-Candia B, Millan-PerezPeña L, Salinas-Stefanon EM. | 09/9/2017 |
| the presences of Nav1.1, Nav1.6, Navbeta1 and Navbeta3 mRNA and their reduced levels in rat SAN during aging. | Age-dependent alterations of voltage-gated Na(+) channel isoforms in rat sinoatrial node.
Huang X, Du Y, Yang P, Lin S, Xi Y, Yang Z, Ma A. | 09/24/2016 |
| The beta1 subunit silencing reduced the expression of Nav1.1, Nav1.3 and Nav1.6 isoforms, whereas the Nav 1.2 isoform expression remained unaltered. | Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression.
Baroni D, Picco C, Barbieri R, Moran O. | 08/23/2014 |
| the existence of the putative disulfide bridge in the Ig-like extracellular domain of the beta1 subunit and its disruption in the epileptogenic C121W mutant was demonstrated. | Identification of an intra-molecular disulfide bond in the sodium channel β1-subunit.
Barbieri R, Baroni D, Moran O. | 05/26/2012 |
| Wild-type (WT) NaVbeta1 subunit is protective against increased channel excitability of seizure-causing mechanism induced by elevated temperature; protection is lost in the absence of WT beta1 subunit or with expression of beta1 (Cys121Trp) mutation. | A thermoprotective role of the sodium channel β1 subunit is lost with the β1 (C121W) mutation.
Egri C, Vilin YY, Ruben PC. | 04/28/2012 |
| Gene silencing also produces a reduction in potassiun channel interacting protein 2(KChIP2) messenger RNA and protein as well as potassium channels. | Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents.
Deschênes I, Armoundas AA, Jones SP, Tomaselli GF., Free PMC Article | 01/21/2010 |
| that sodium channel Na(v)1.1, Na(v)1.3 and beta(1) subunit up-regulation at the mRNA and protein levels of SER hippocampus might contribute to the generation of epileptiform activity and underlie the observed seizure phenotype in SER. | Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat.
Guo F, Yu N, Cai JQ, Quinn T, Zong ZH, Zeng YJ, Hao LY. | 01/21/2010 |
| Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons | Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons.
Davis TH, Chen C, Isom LL. | 01/21/2010 |
| beta1 voltage-gated sodium channel gene expression in the axotomized facial nucleus decreased compared to controls as soon as day post-lesion 3. | Modulation of the beta1-3 voltage-gated sodium channels in rat vestibular and facial nuclei after unilateral labyrinthectomy and facial nerve section: an in situ hybridization study.
Vassias I, Patko T, Vidal PP, de Waele C. | 01/21/2010 |