| Proanthocyanidins mitigate bile acid-induced changes in GSTT2 levels in a panel of racially diverse patient-derived primary esophageal cell cultures. | Proanthocyanidins mitigate bile acid-induced changes in GSTT2 levels in a panel of racially diverse patient-derived primary esophageal cell cultures.
Weh KM, Turgeon DK, Rubenstein JH, Clarke JL, Howell AB, Chang AC, Kresty LA., Free PMC Article | 04/23/2022 |
| Increased levels of GSTT2 in esophageal tissues of African American individuals might protect them from GERD-induced damage and contribute to the low incidence of esophageal adenocarcinoma in this population. | Constitutively Higher Level of GSTT2 in Esophageal Tissues From African Americans Protects Cells Against DNA Damage.
Ferrer-Torres D, Nancarrow DJ, Steinberg H, Wang Z, Kuick R, Weh KM, Mills RE, Ray D, Ray P, Lin J, Chang AC, Reddy RM, Orringer MB, Canto MI, Shaheen NJ, Kresty LA, Chak A, Wang TD, Rubenstein JH, Beer DG., Free PMC Article | 05/4/2019 |
| analysis of glutathione S-transferase copy number variation alters lung gene expression | Glutathione S-transferase copy number variation alters lung gene expression.
Butler MW, Hackett NR, Salit J, Strulovici-Barel Y, Omberg L, Mezey J, Crystal RG., Free PMC Article | 01/28/2012 |
| Polyphenol metabolites did not affect cell number but significantly upregulated GSTT2 expression and decreased COX-2. | Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97).
Miene C, Weise A, Glei M. | 09/17/2011 |
| GSTM1 (1p13.3) and GSTT2 (22q11.23) showed a statistically significant association of non-null genotypes at both loci with an additive effect for increased vulnerability to schizophrenia | Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia.
Rodríguez-Santiago B, Brunet A, Sobrino B, Serra-Juhé C, Flores R, Armengol L, Vilella E, Gabau E, Guitart M, Guillamat R, Martorell L, Valero J, Gutiérrez-Zotes A, Labad A, Carracedo A, Estivill X, Pérez-Jurado LA, Rodríguez-Santiago B, Brunet A, Sobrino B, Serra-Juhé C, Flores R, Armengol L, Vilella E, Gabau E, Guitart M, Guillamat R, Martorell L, Valero J, Gutiérrez-Zotes A, Labad A, Carracedo A, Estivill X, Pérez-Jurado LA. | 01/15/2011 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia.
Rodríguez-Santiago B, Brunet A, Sobrino B, Serra-Juhé C, Flores R, Armengol L, Vilella E, Gabau E, Guitart M, Guillamat R, Martorell L, Valero J, Gutiérrez-Zotes A, Labad A, Carracedo A, Estivill X, Pérez-Jurado LA, Rodríguez-Santiago B, Brunet A, Sobrino B, Serra-Juhé C, Flores R, Armengol L, Vilella E, Gabau E, Guitart M, Guillamat R, Martorell L, Valero J, Gutiérrez-Zotes A, Labad A, Carracedo A, Estivill X, Pérez-Jurado LA. | 06/24/2009 |
| PAH-DNA adduct formation could be modulated by common genetic variants in GSTT2 in African American, Dominican and Caucasian mothers and newborns. | Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.
Wang S, Chanock S, Tang D, Li Z, Jedrychowski W, Perera FP, Wang S, Chanock S, Tang D, Li Z, Jedrychowski W, Perera FP., Free PMC Articles: PMC3171162, PMC3171162 | 01/21/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | See all PubMed (4) articlesAlcohol, tobacco and genetic susceptibility in relation to cancers of the upper aerodigestive tract in northern Italy.
Canova C, Richiardi L, Merletti F, Pentenero M, Gervasio C, Tanturri G, Garzino-Demo P, Pecorari G, Talamini R, Barzan L, Sulfaro S, Franchini G, Muzzolini C, Bordin S, Pugliese GN, Macrì E, Simonato L. Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns.
Wang S, Chanock S, Tang D, Li Z, Edwards S, Jedrychowski W, Perera FP. Methods for detecting interactions between genetic polymorphisms and prenatal environment exposure with a mother-child design.
Wang S, Zheng T, Chanock S, Jedrychowski W, Perera FP. Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.
Wang S, Chanock S, Tang D, Li Z, Jedrychowski W, Perera FP, Wang S, Chanock S, Tang D, Li Z, Jedrychowski W, Perera FP. | 04/3/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (12) articlesGlutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.
Moyer AM, Sun Z, Batzler AJ, Li L, Schaid DJ, Yang P, Weinshilboum RM. Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism.
Gemignani F, Neri M, Bottari F, Barale R, Canessa PA, Canzian F, Ceppi M, Spitaleri I, Cipollini M, Ivaldi GP, Mencoboni M, Scaruffi P, Tonini GP, Ugolini D, Mutti L, Bonassi S, Landi S. Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori.
Tatemichi M, Iwasaki M, Sasazuki S, Tsugane S. Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.
Canova C, Hashibe M, Simonato L, Nelis M, Metspalu A, Lagiou P, Trichopoulos D, Ahrens W, Pigeot I, Merletti F, Richiardi L, Talamini R, Barzan L, Macfarlane GJ, Macfarlane TV, Holcátová I, Bencko V, Benhamou S, Bouchardy C, Kjaerheim K, Lowry R, Agudo A, Castellsagué X, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy CM, Marron M, Brennan P. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.
Velez DR, Fortunato S, Thorsen P, Lombardi SJ, Williams SM, Menon R. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ. Association study between the genetic polymorphisms of glutathione-related enzymes and schizophrenia in a Japanese population.
Matsuzawa D, Hashimoto K, Hashimoto T, Shimizu E, Watanabe H, Fujita Y, Iyo M. A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.
Zienolddiny S, Campa D, Lind H, Ryberg D, Skaug V, Stangeland LB, Canzian F, Haugen A. Association study between polymorphisms in glutathione-related genes and methamphetamine use disorder in a Japanese population.
Hashimoto T, Hashimoto K, Miyatake R, Matsuzawa D, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Iyo M. GSTT2 promoter polymorphisms and colorectal cancer risk.
Jang SG, Kim IJ, Kang HC, Park HW, Ahn SA, Yoon HJ, Kim K, Shin HR, Lee JS, Park JG, Jang SG, Kim IJ, Kang HC, Park HW, Ahn SA, Yoon HJ, Kim K, Shin HR, Lee JS, Park JG. A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Landi S, Gemignani F, Moreno V, Gioia-Patricola L, Chabrier A, Guino E, Navarro M, de Oca J, Capellà G, Canzian F, Bellvitge Colorectal Cancer Study Group. Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples.
Liu Y, Yoshimura K, Hanaoka T, Ohnami S, Ohnami S, Kohno T, Yoshida T, Sakamoto H, Sobue T, Tsugane S. | 03/13/2008 |
| single nucleotide polymorphisms and haplotypes of the GSTT2 promoter region are associated with colorectal cancer risk in the Korean population | GSTT2 promoter polymorphisms and colorectal cancer risk.
Jang SG, Kim IJ, Kang HC, Park HW, Ahn SA, Yoon HJ, Kim K, Shin HR, Lee JS, Park JG, Jang SG, Kim IJ, Kang HC, Park HW, Ahn SA, Yoon HJ, Kim K, Shin HR, Lee JS, Park JG., Free PMC Articles: PMC1793996, PMC1793996 | 01/21/2010 |
| dinitrosyl-diglutathionyl-iron complex, a natural carrier of nitric oxide, binds with extraordinary affinity to GSTA1-1, which is explained by molecular modeling and related to molecular evolution | The specific interaction of dinitrosyl-diglutathionyl-iron complex, a natural NO carrier, with the glutathione transferase superfamily: suggestion for an evolutionary pressure in the direction of the storage of nitric oxide.
De Maria F, Pedersen JZ, Caccuri AM, Antonini G, Turella P, Stella L, Lo Bello M, Federici G, Ricci G. | 01/21/2010 |