| Effect of Taspine hydrochloride on the repair of rat skin wounds by regulating keratinocyte growth factor signal. | Effect of Taspine hydrochloride on the repair of rat skin wounds by regulating keratinocyte growth factor signal.
Wang X, Gao Y, Sun X., Free PMC Article | 02/19/2022 |
| MiR-199a-3p inhibits the proliferation, migration, and invasion of endothelial cells and retinal pericytes of diabetic retinopathy rats through regulating FGF7 via EGFR/PI3K/AKT pathway. | MiR-199a-3p inhibits the proliferation, migration, and invasion of endothelial cells and retinal pericytes of diabetic retinopathy rats through regulating FGF7 via EGFR/PI3K/AKT pathway.
Zhou L, Zhang S, Zhang L, Li F, Sun H, Feng J. | 11/27/2021 |
| Silencing fibroblast growth factor 7 inhibits krypton laser-induced choroidal neovascularization in a rat model. | Silencing fibroblast growth factor 7 inhibits krypton laser-induced choroidal neovascularization in a rat model.
Zhang C, Han M, Wu S. | 08/15/2020 |
| findings illustrate a role for miR-455-3p-1 in modulating FGF7-RAS/ERK signaling and suggest that an agomir of miR-455-3p-1 could inhibit the proliferation of PASMCs and mitigate PAH in vivo. | Mir-455-3p-1 represses FGF7 expression to inhibit pulmonary arterial hypertension through inhibiting the RAS/ERK signaling pathway.
Zhou C, Chen Y, Kang W, Lv H, Fang Z, Yan F, Li L, Zhang W, Shi J. | 06/20/2020 |
| findings demonstrate that KGF-1 promotes fibroblast contraction and accelerates wound contraction via the TGF-beta1/Smad signaling pathway in a double-paracrine manner. | KGF-1 accelerates wound contraction through the TGF-β1/Smad signaling pathway in a double-paracrine manner.
Peng Y, Wu S, Tang Q, Li S, Peng C., Free PMC Article | 12/14/2019 |
| HGF and KGF gene silencing inhibits ultraviolet raysinduced corneal epithelial proliferation and corneal neovascularization and may function as novel targets for corneal wound healing. | Effects of HGF and KGF gene silencing on vascular endothelial growth factor and its receptors in rat ultraviolet radiation‑induced corneal neovascularization.
He M, Han T, Wang Y, Wu YH, Qin WS, Du LZ, Zhao CQ. | 08/3/2019 |
| The findings of the present study indicated that KGF, CTGF and TGF-beta have biological roles in progression of CsA- and PNT- induced GO. KGF plays a greater role in CsA- induced GO than in PNT- induced GO. Meanwhile, CTGF and TGF-beta play a role in PNT- induced GO greater than in CsA- induced GO. | Biological roles of KGF, CTGF and TGF-β in cyclosporine-A- and phenytoin- induced gingival overgrowth: A comparative experimental animal study.
Al-Hamilly NS, Radwan LR, Abdul-Rahman M, Mourad MI, Grawish ME. | 02/18/2017 |
| These data demonstrate that administration of MSCs to the inflammation-insulted AT-II cells may ameliorate the impairments through a KGF-dependent PI3K/AKT/mTOR signaling pathway. | Mesenchymal stem cells ameliorate inflammatory cytokine-induced impairment of AT-II cells through a keratinocyte growth factor-dependent PI3K/Akt/mTOR signaling pathway.
Li J, Huang S, Zhang J, Feng C, Gao D, Yao B, Wu X, Fu X., Free PMC Article | 02/18/2017 |
| The primary role of both KGF1 and FGF2 appeared to be in the proliferation and migration of keratinocytes | Keratinocyte growth factor 1, fibroblast growth factor 2 and 10 in the healing tympanic membrane following perforation in rats.
Santa Maria PL, Redmond SL, Atlas MD, Ghassemifar R. | 07/16/2011 |
| KGF may have a role in ameliorating radiation-induced pulmonary injury in rats | Keratinocyte growth factor (KGF) gene therapy mediated by an attenuated form of Salmonella typhimurium ameliorates radiation induced pulmonary injury in rats.
Liu CJ, Ha XQ, Jiang JJ, Lv TD, Wu C. | 07/9/2011 |
| KGF promotes preadipocyte proliferation by an autocrine mechanism that involves activation of the PI3K/Akt signaling pathway | Keratinocyte growth factor promotes preadipocyte proliferation via an autocrine mechanism.
Zhang T, Guan H, Yang K. | 08/16/2010 |
| the effects of KGF on duct cell proliferation are mediated by the MEK-ERK1/2 pathway, while the KGF-induced cell differentiation is mediated by the PI3K/AKT pathway | Mechanisms of KGF mediated signaling in pancreatic duct cell proliferation and differentiation.
Uzan B, Figeac F, Portha B, Movassat J., Free PMC Article | 01/21/2010 |
| retention of the AT2 cell phenotype by KGF involves c-Jun and suggest that activation of c-Jun kinase may be an important determinant of maintenance of AT2 cell phenotype | Effects of KGF on alveolar epithelial cell transdifferentiation are mediated by JNK signaling.
Qiao R, Yan W, Clavijo C, Mehrian-Shai R, Zhong Q, Kim KJ, Ann D, Crandall ED, Borok Z., Free PMC Article | 01/21/2010 |
| FGF-7, most likely through its effect on the vascular bed, is required for normal early postnatal alveolar formation from secondary crests. | A critical role for fibroblast growth factor-7 during early alveolar formation in the neonatal rat.
Padela S, Yi M, Cabacungan J, Shek S, Belcastro R, Masood A, Jankov RP, Tanswell AK. | 01/21/2010 |
| Keratinocyte growth factor may promote alveolar epithelial repair through several mechanisms involved in cell migration | Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro.
Galiacy S, Planus E, Lepetit H, Féréol S, Laurent V, Ware L, Isabey D, Matthay M, Harf A, d'Ortho MP. | 01/21/2010 |
| Exogenous administered KGF cDNA causes increases in IGF-I, IGF-BP3, FGF, and collagen IV and decreases TGF-beta concentration. KGF gene transfer accelerates wound healing without causing an increase in collagen I or III. | Liposomal gene transfer of keratinocyte growth factor improves wound healing by altering growth factor and collagen expression.
Pereira CT, Herndon DN, Rocker R, Jeschke MG. | 01/21/2010 |
| stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3 | Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3.
Karvinen S, Pasonen-Seppänen S, Hyttinen JM, Pienimäki JP, Törrönen K, Jokela TA, Tammi MI, Tammi R. | 01/21/2010 |
| KGF improves alterations of lung permeability and bronchial epithelium in allergic rats | Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats.
Tillie-Leblond I, Gosset P, Le Berre R, Janin A, Prangère T, Tonnel AB, Guery BP. | 01/21/2010 |
| data suggest that fibroblast growth factors FGF-7 and FGF-10 contribute to the regeneration and differentiation of acinar cells and angiogenesis in acute pancreatitis through the keratinocyte growth factor receptor | Differential distribution of fibroblast growth factor (FGF)-7 and FGF-10 in L-arginine-induced acute pancreatitis.
Ishiwata T, Naito Z, Lu YP, Kawahara K, Fujii T, Kawamoto Y, Teduka K, Sugisaki Y. | 01/21/2010 |
| KGF stimulates lipogenesis in alveolar type II cells by a coordinated expression of lipogenic enzymes and transport proteins regulated by C/EBP isoforms and SREBP-1c | Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells.
Mason RJ, Pan T, Edeen KE, Nielsen LD, Zhang F, Longphre M, Eckart MR, Neben S., Free PMC Article | 01/21/2010 |
| Decreased gene expression of FGF-7 in the rat hypoplastic lung suggests that pulmonary hypoplasia in nitrofen-induced congenital diaphragmatic hernia rat may be caused by reduced synthesis of FGF-7 during lung morphogenesis. | Gene expression of fibroblast growth factors 10 and 7 is downregulated in the lung of nitrofen-induced diaphragmatic hernia in rats.
Teramoto H, Yoneda A, Puri P. | 01/21/2010 |