| Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium. | Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium.
Casini A, Vivacqua G, Vaccaro R, Renzi A, Leone S, Pannarale L, Franchitto A, Onori P, Mancinelli R, Gaudio E., Free PMC Article | 11/13/2023 |
| Blockade of the orexin 1-receptors and 'cocaine- and amphetamine-regulated transcript' in the nucleus accumbens shell alters impulse control in rats. | Blockade of the orexin 1-receptors and 'cocaine- and amphetamine-regulated transcript' in the nucleus accumbens shell alters impulse control in rats.
Schuller J, Koch M. | 01/14/2023 |
| CART decreases islet blood flow, but has no effect on total pancreatic blood flow and glucose tolerance in anesthetized rats. | CART decreases islet blood flow, but has no effect on total pancreatic blood flow and glucose tolerance in anesthetized rats.
Drott CJ, Norman D, Espes D. | 11/22/2021 |
| Overcoming Stress, Hunger, and Pain: Cocaine- and Amphetamine-Regulated Transcript Peptide's Promise. | Overcoming Stress, Hunger, and Pain: Cocaine- and Amphetamine-Regulated Transcript Peptide's Promise.
Samson WK, Salvemini D, Yosten GLC., Free PMC Article | 10/23/2021 |
| Cocaine- and amphetamine-regulated transcript peptide promotes reward seeking behavior in socially isolated rats. | Cocaine- and amphetamine-regulated transcript peptide promotes reward seeking behavior in socially isolated rats.
Somalwar AR, Choudhary AG, Balasubramanian N, Sakharkar AJ, Subhedar NK, Kokare DM. | 04/24/2021 |
| Study proposes that CARTp acting in the rostral ventrolateral medulla may involvement in the cardiovascular regulation either by increases in the blood pressure or by decreases in the baroreflex sensitivity in rats. | Roles of cocaine- and amphetamine-regulated transcript peptide in the rostral ventrolateral medulla in cardiovascular regulation in rats.
Lai CC, Yuan ZF, Chu LY, Chuang KT, Lin HH. | 06/27/2020 |
| impaired CART mRNA expression in the anterior Paraventricular nucleus and Lateral hypothalamic area could be related to the aberrant feeding behaviour of dehydration-induced anorexic rats but not to their deregulated HPT axis function. | Impaired hypothalamic cocaine- and amphetamine-regulated transcript expression in lateral hypothalamic area and paraventricular nuclei of dehydration-induced anorexic rats.
García-Luna C, Soberanes-Chávez P, de Gortari P. | 07/14/2018 |
| The results indicate that Cocaine and Amphetamine-Regulated Transcript (CART) can directly affect the physiological release of hormones in pituitary cells of starved animals. | The effect of CART on pituitary hormones release from cultured pituitary cells harvested from fasted and fed ad libitum male rats.
Chmielowska M, Baranowska B, Wolinska-Witort E, Martynska L, Kalisz M, Litwiniuk A, Bik W. | 02/24/2018 |
| As the observed results are in agreement with data regarding the CART mRNA and protein expression in the brain reward pathway in opioid addiction phases, it may be suggested that evaluation of CART peptide level in CSF or plasma could be a suitable marker which reflects the rises and falls of the peptide concentration in brain in the development of opioid addiction | Evaluation of CART peptide level in rat plasma and CSF: Possible role as a biomarker in opioid addiction.
Bakhtazad A, Vousooghi N, Garmabi B, Zarrindast MR. | 01/27/2018 |
| Results suggest that CART plays an important role in recognition memory and that these effects may be mediated by NMDA receptors-ERK signaling in the entorhinal/perirhinal -hippocampal circuit. | Pro-cognitive action of CART is mediated via ERK in the hippocampus.
Bharne AP, Borkar CD, Bodakuntla S, Lahiri M, Subhedar NK, Kokare DM. | 01/13/2018 |
| CART is important for maintaining the beta-cell phenotype. | Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes.
Shcherbina L, Edlund A, Esguerra JL, Abels M, Zhou Y, Ottosson-Laakso E, Wollheim CB, Hansson O, Eliasson L, Wierup N. | 11/25/2017 |
| Study found that the distribution and intensity of CART staining in the nodose ganglion looked identical in fed and fasted rats when observed under blinded conditions and the density of CART-positive profiles across the ganglion was not significantly different in fed and fasted rats. | Levels of Cocaine- and Amphetamine-Regulated Transcript in Vagal Afferents in the Mouse Are Unaltered in Response to Metabolic Challenges.
Yuan X, Huang Y, Shah S, Wu H, Gautron L., Free PMC Article | 10/28/2017 |
| Cocaine- and amphetamine-regulated transcript (CART) mRNA and protein were both up-regulated in morphine-administered animals and also in the withdrawal group in the nucleus accumbens (NAc), striatum and prefrontal cortex (PFC). In the addicted group, CART mRNA and protein were both down-regulated in NAc and striatum. | CART peptide and opioid addiction: Expression changes in male rat brain.
Bakhtazad A, Vousooghi N, Garmabi B, Zarrindast MR. | 06/10/2017 |
| These findings suggest that islet-derived CART is involved, at least in part, in high glucose-potentiated pancreatic beta-cell function. | Glucose enhances rat islet function via stimulating CART expression.
Xu W, Zhang Y, Bai M, Zhou F, Deng R, Ji X, Zhang J, Liu Y, Zhou L, Wang X. | 05/27/2017 |
| These results suggest that endogenous CART might closely interact with the dopamine containing substantia nigra-striatal pathway which is known to profoundly influence the motor system | CART modulates the effects of levodopa in rat model of Parkinson's disease.
Upadhya MA, Shelkar GP, Subhedar NK, Kokare DM. | 10/22/2016 |
| The study gives rise to the assumption that high blood pressure can be a factor that intensifies CART secretion | Quantitative evaluation of CART-containing cells in urinary bladder of rats with renovascular hypertension.
Janiuk I, Kasacka I., Free PMC Article | 04/23/2016 |
| Results suggest that there might be two partly overlapping brain circuits involved in the neurobiology of binge eating, both driven by CART | Differential expression of CART in feeding and reward circuits in binge eating rat model.
Bharne AP, Borkar CD, Subhedar NK, Kokare DM. | 04/2/2016 |
| Results suggest that oxidative stress in the brain participates in regulating NPY/CART-mediated appetite control in amphetamine-treated rats. | Involvement of oxidative stress in the regulation of NPY/CART-mediated appetite control in amphetamine-treated rats.
Hsieh YS, Chen PN, Yu CH, Chen CH, Tsai TT, Kuo DY. | 02/27/2016 |
| Elevated circulating progesterone concentration up-regulated NPY and down-regulated CART genes expression in hypothalamus of females and caused an increase in food intake and white adipose tissue mass. | Enhanced food intake by progesterone-treated female rats is related to changes in neuropeptide genes expression in hypothalamus.
Stelmańska E, Sucajtys-Szulc E. | 10/31/2015 |
| Renal vascular reactivity is associated with up regulation of renal endothelin receptors type A. | Lipopolysaccharide enhanced renal vascular response to endothelin-1 through ETA overexpression in portal hypertensive rats.
Chuang CL, Huang HC, Chang CC, Lee FY, Wu JC, Lee JY, Hsieh HG, Lee SD. | 09/12/2015 |
| Cart expression decreased in the arcuate nucleus of the hypothalamus in polydipsic rats. | Differences in the structure of drinking, cart expression and dopamine turnover between polydipsic and non polydipsic rats in the quinpirole model of psychotic polydipsia.
Schepisi C, Cianci S, Bedse G, Fu J, Gaetani S, Nencini P. | 08/29/2015 |
| Acumbal-CART peptide reduces anxiety-like behavior in a dose-dependent manner. | Microinjection of cocaine- and amphetamine-regulated transcript 55-102 peptide into the nucleus accumbens could modulate anxiety-related behavior in rats.
Yoon HS, Adachi N, Kunugi H. | 08/8/2015 |
| We demonstrated that renovascular hypertension alters the number and immunoreactivity of CART-containing cells in adrenal glands | Quantitative and qualitative evaluation of CART-containing cells in adrenal glands of male rats with hypertension.
Kasacka I, Piotrowska Ż, Knaś M, Lewandowska A. | 05/23/2015 |
| These data demonstrate that CART peptide-expressing neurons are belong to a sparcely branched neuronal system. | [Structural and functional organization of cart peptide-expressing neurons in brain amygdala].
Akhmadeev AV, Kalimullina LB. | 02/14/2015 |
| CART peptide is effective in blunting dopaine- and cocaine-mediated locomoter activity in both males and females. | Cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine- and cocaine-mediated locomotor activity in both male and female rats: lack of sex differences.
Job MO, Perry J, Shen LL, Kuhar MJ., Free PMC Article | 12/6/2014 |