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    METTL5 methyltransferase 5, N6-adenosine [ Homo sapiens (human) ]

    Gene ID: 29081, updated on 26-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    METTL5: A Potential Biomarker for Nonsmall Cell Lung Cancer That Promotes Cancer Cell Proliferation by Interacting with IGF2BP3.

    METTL5: A Potential Biomarker for Nonsmall Cell Lung Cancer That Promotes Cancer Cell Proliferation by Interacting with IGF2BP3.
    Gong S, Liu H, Gou H, Sun W.

    09/20/2024
    Biological significance of METTL5 in atherosclerosis: comprehensive analysis of single-cell and bulk RNA sequencing data.

    Biological significance of METTL5 in atherosclerosis: comprehensive analysis of single-cell and bulk RNA sequencing data.
    Wu J, Wang L, Xi S, Ma C, Zou F, Fang G, Liu F, Wang X, Qu L., Free PMC Article

    06/1/2024
    The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.

    The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.
    Wang Q, Huang Y, Zhu Y, Zhang W, Wang B, Du X, Dai Q, Zhang F, Fang Z., Free PMC Article

    05/20/2024
    Knockdown of METTL5 inhibits the Myc pathway to downregulate PD-L1 expression and inhibits immune escape of hepatocellular carcinoma cells.

    Knockdown of METTL5 inhibits the Myc pathway to downregulate PD-L1 expression and inhibits immune escape of hepatocellular carcinoma cells.
    Xu W, Liu S, Zhang G, Liu J, Cao G.

    08/2/2023
    METTL5 stabilizes c-Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression.

    METTL5 stabilizes c-Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression.
    Xia P, Zhang H, Lu H, Xu K, Jiang X, Jiang Y, Gongye X, Chen Z, Liu J, Chen X, Ma W, Zhang Z, Yuan Y., Free PMC Article

    03/16/2023
    Three Afghani siblings with a novel homozygous variant and further delineation of the clinical features of METTL5 related intellectual disability syndrome.

    Three Afghani siblings with a novel homozygous variant and further delineation of the clinical features of METTL5 related intellectual disability syndrome.
    Torun D, Arslan M, Çavdarlı B, Akar H, Cram DS.

    01/28/2023
    The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma.

    The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma.
    Liu X, Ma H, Ma L, Li K, Kang Y., Free PMC Article

    04/16/2022
    Ribosome 18S m(6)A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.

    Ribosome 18S m(6)A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.
    Rong B, Zhang Q, Wan J, Xing S, Dai R, Li Y, Cai J, Xie J, Song Y, Chen J, Zhang L, Yan G, Zhang W, Gao H, Han JJ, Qu Q, Ma H, Tian Y, Lan F.

    12/25/2021
    Analysis of the role of METTL5 as a hub gene in lung adenocarcinoma based on a weighted gene co-expression network.

    Analysis of the role of METTL5 as a hub gene in lung adenocarcinoma based on a weighted gene co-expression network.
    Yan X, Zhao X, Yan Q, Wang Y, Zhang C.

    09/25/2021
    Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima.

    Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima.
    Yu D, Kaur G, Blumenthal RM, Zhang X, Cheng X., Free PMC Article

    08/28/2021
    METTL5-TRMT112 partners act by extruding the adenosine to be modified from a double-stranded nucleic acid.

    The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
    van Tran N, Ernst FGM, Hawley BR, Zorbas C, Ulryck N, Hackert P, Bohnsack KE, Bohnsack MT, Jaffrey SR, Graille M, Lafontaine DLJ., Free PMC Article

    12/7/2019
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