| CCDC66 mutations are associated with high myopia through affected cell mitosis. | CCDC66 mutations are associated with high myopia through affected cell mitosis.
Chen X, Tong P, Jiang Y, Cheng Z, Zang L, Yang Z, Lan W, Xia K, Hu Z, Tian Q. | 02/23/2024 |
| CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins. | CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins.
Odabasi E, Conkar D, Deretic J, Batman U, Frikstad KM, Patzke S, Firat-Karalar EN. | 02/11/2023 |
| Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer. | Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer.
Mo Y, Lu Q, Zhang Q, Chen J, Deng Y, Zhang K, Tao R, Liu W, Wang Y., Free PMC Article | 03/5/2022 |
| Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression. | Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression.
Qi L, Wang W, Zhao G, Jiang H, Zhang Y, Zhao D, Jin H, Xu H, Yu H., Free PMC Article | 08/7/2021 |
| Circular RNA CCDC66 facilitates abdominal aortic aneurysm through the overexpression of CCDC66. | Circular RNA CCDC66 facilitates abdominal aortic aneurysm through the overexpression of CCDC66.
Yang R, Wang Z, Meng G, Hua L. | 05/8/2021 |
| CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis. | CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis.
Zhang Q, Miao Y, Fu Q, Hu H, Chen H, Zeng A, Jin Y, Jiang Y, Qian L, Wu L, Xu L, Wang G, Qiu L, Huang X, Xia Y. | 12/19/2020 |
| Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors. | Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Conkar D, Bayraktar H, Firat-Karalar EN., Free PMC Article | 11/21/2020 |
| Circ-CCDC66 accelerates proliferation and invasion of gastric cancer via binding to miRNA-1238-3p. | Circ-CCDC66 accelerates proliferation and invasion of gastric cancer via binding to miRNA-1238-3p.
Yang M, Wang GY, Qian H, Ji XY, Liu CY, Zeng XH, Lv J, Shi YX. | 09/19/2020 |
| this is the first report revealing that cir-CCDC66 modulates DCX expression through sponging miR-488-3p and thus participates in the onset of Hirschsprung's disease. | Circular RNA CCDC66 targets DCX to regulate cell proliferation and migration by sponging miR-488-3p in Hirschsprung's disease.
Wen Z, Shen Q, Zhang H, Su Y, Zhu Z, Chen G, Peng L, Li H, Du C, Xie H, Xu X, Tang W. | 05/16/2020 |
| HGF/c-Met regulates expression of SAE2 and cirRNA CCDC66 to increase epithelial-to-mesenchymal transition and drug resistance of lung adenocarcinoma cells. | The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells.
Joseph NA, Chiou SH, Lung Z, Yang CL, Lin TY, Chang HW, Sun HS, Gupta SK, Yen L, Wang SD, Chow KC., Free PMC Article | 10/26/2019 |
| Results associate a distinct retinal dystrophy phenotype with nicotinamide-nucleotide adenylyltransferase 1 protein (NMNAT1) mutation and suggest coiled-coil domain containing 66 (CCDC66) should not be considered a retinal dystrophy candidate gene. | Genome-wide linkage and sequence analysis challenge CCDC66 as a human retinal dystrophy candidate gene and support a distinct NMNAT1-related fundus phenotype.
Khan AO, Budde BS, Nürnberg P, Kawalia A, Lenzner S, Bolz HJ. | 08/11/2018 |
| In-depth characterization revealed that circCCDC66 exerts its function via regulation of a subset of oncogenes, and knockdown of circCCDC66 inhibited tumor growth and cancer invasion in xenograft and orthotopic mouse models, respectively. Taken together, these findings highlight a novel oncogenic function of circRNA in cancer progression and metastasis. | Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis.
Hsiao KY, Lin YC, Gupta SK, Chang N, Yen L, Sun HS, Tsai SJ., Free PMC Article | 09/16/2017 |
| this study identifies CCDC66 as a targeting factor for centrosome and cilium proteins | The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking.
Conkar D, Culfa E, Odabasi E, Rauniyar N, Yates JR 3rd, Firat-Karalar EN., Free PMC Article | 05/6/2017 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |