| The present findings suggest that prolyl 3-hydroxylation incrementally regulates collagen fibril diameter in tendon. | Developmental Stage-dependent Regulation of Prolyl 3-Hydroxylation in Tendon Type I Collagen.
Taga Y, Kusubata M, Ogawa-Goto K, Hattori S., Free PMC Article | 05/21/2016 |
| These observations support a signaling network among JNKs, Smads, Snail1, and cortactin to regulate the invasion of MDA-MB-231 cells embedded in 3D collagen I, which may be targeted during screening of anti-invasion reagents. | Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation.
Lee MS, Kim S, Kim BG, Won C, Nam SH, Kang S, Kim HJ, Kang M, Ryu J, Song HE, Lee D, Ye SK, Jeon NL, Kim TY, Cho NH, Lee JW. | 09/13/2014 |
| The experiment results demonstrated that the aggregates of collagen incurred in the range of 0.30-0.45 mg/mL, while the more complicated ones emerged at higher concentrations of collagen (0.75 and 1.05 mg/mL). | The aggregation behavior of native collagen in dilute solution studied by intrinsic fluorescence and external probing.
Wu K, Liu W, Li G. | 06/15/2013 |
| Two subsystems of meniscal collagen and their different thermal stabilities. | Two subsystems of meniscal collagen and their different thermal stabilities.
Ignatieva NY, Zakharkina OL, Lunin VV, Baratova LA, Grokhovskaya TE, Balalaeva IV, Sergeeva EA. | 11/17/2012 |
| These results imply that the fibril form of collagen plays a potential role in inhibiting the growth of cancer cells. | Delay of cell cycle progression and induction death of cancer cells on type I collagen fibrils [corrected].
Sasaki J, Fujisaki H, Adachi E, Irie S, Hattori S. | 10/1/2011 |
| Data show that biglycan, collagen type I, collagen type II, decorin, and versican were significantly affected by vibration duration, frequency, and amplitude. | Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi.
Desmoulin GT, Reno CR, Hunter CJ. | 10/4/2010 |
| Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen. | Matrix-specific suppression of integrin activation in shear stress signaling.
Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA., Free PMC Article | 01/21/2010 |
| In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen | Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gammadelta (WC1+) T cells and CD 68+ cells.
Wangoo A, Johnson L, Gough J, Ackbar R, Inglut S, Hicks D, Spencer Y, Hewinson G, Vordermeier M. | 01/21/2010 |
| A molecular model of collagen hydration is used to validate centrifugal dehydration force (CDF) and re-hydration isotherm (RHI) methods to measure and characterize hydration compartments on bovine tendon. | Verification of simple hydration/dehydration methods to characterize multiple water compartments on tendon type 1 collagen.
Cameron IL, Short NJ, Fullerton GD. | 01/21/2010 |
| These results demonstrate a novel and important functional role of the DDR2 extracellular domain that may contribute to collagen regulation via modulation of fibrillogenesis. | Discoidin domain receptor 2 inhibits fibrillogenesis of collagen type 1.
Mihai C, Iscru DF, Druhan LJ, Elton TS, Agarwal G. | 01/21/2010 |
| specific ADAMTS-2 domains cleave the aminopropeptide of fibrillar procollagens types I-III and V | Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V.
Colige A, Ruggiero F, Vandenberghe I, Dubail J, Kesteloot F, Van Beeumen J, Beschin A, Brys L, Lapière CM, Nusgens B. | 01/21/2010 |