| GPIbalpha-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis. | GPIbα-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis.
Ellis ML, Terreaux A, Alwis I, Smythe R, Perdomo J, Eckly A, Cranmer SL, Passam FH, Maclean J, Schoenwaelder SM, Ruggeri ZM, Lanza F, Taoudi S, Yuan Y, Jackson SP. | 02/14/2024 |
| Integrated Proteomics and Metabolomics Analyses of Serum in Chinese Patients with Severe and Active Graves' Orbitopathy: A Cross-sectional Study. | Integrated Proteomics and Metabolomics Analyses of Serum in Chinese Patients with Severe and Active Graves' Orbitopathy: A Cross-sectional Study.
Shi TT, Liu HY, Zhu XR, Xin Z, Hua L, Xie RR, Sun R, Cao X, Yang JK. | 08/9/2023 |
| Low alpha-Thrombin/GPIbalpha Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients. | Low α-Thrombin/GPIbα Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients.
Zaid Y, Khalki L, Jalali F, Tijani Y, Zaid N, Naya A, Oudghiri M, Akarid K, Agbani EO, Guessous F., Free PMC Article | 07/26/2023 |
| Comprehensive analysis of platelet glycoprotein Ibalpha ectodomain glycosylation. | Comprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation.
Hollenhorst MA, Tiemeyer KH, Mahoney KE, Aoki K, Ishihara M, Lowery SC, Rangel-Angarita V, Bertozzi CR, Malaker SA., Free PMC Article | 03/31/2023 |
| Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia. | Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia.
Dib F, Quéméner A, Bayart S, Boisseau P, Babuty A, Trossaërt M, Sigaud M, Ternisien C, Drillaud N, Eveillard M, Guillet B, Béné MC, Fouassier M. | 12/3/2022 |
| A GP1BA Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome. | A GP1BA Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome.
Skalníková M, Staňo Kozubík K, Trizuljak J, Vrzalová Z, Radová L, Réblová K, Holbová R, Kurucová T, Svozilová H, Štika J, Blaháková I, Dvořáčková B, Prudková M, Stehlíková O, Šmída M, Křen L, Smejkal P, Pospíšilová Š, Doubek M., Free PMC Article | 02/5/2022 |
| Predictive Value of Kozak Gene Polymorphism for Thrombosis in Patients with Philadelphia-Negative MPNs. | Predictive Value of Kozak Gene Polymorphism for Thrombosis in Patients with Philadelphia-Negative MPNs.
El-Ghonemy MS, El-Ashwah S, Denewer M, Soliman EA, El-Baiomy M, Elkerdawy H, El-Sebaie A., Free PMC Article | 11/27/2021 |
| A fibrinolytic snake venom metalloproteinase, mutalysin-II, with antiplatelet activity and targeting capability toward glycoprotein GPIbalpha and glycoprotein GPVI. | A fibrinolytic snake venom metalloproteinase, mutalysin-II, with antiplatelet activity and targeting capability toward glycoprotein GPIbα and glycoprotein GPVI.
Sanchez EF, Alvarenga VG, Oliveira LS, Oliveira DL, Estevao-Costa MI, Flores-Ortiz R, Eble JA. | 07/17/2021 |
| Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis. | Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis.
Yuan D, Shi X, Guo L, Wang G, Zhao Y, Yang Y, Zhang H, Huang Q, Yuan Y., Free PMC Article | 04/17/2021 |
| Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction. | Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction.
Li B, Huang Q, Lin C, Lu R, Wang T, Chen X, Liu Z, Liu Y, Wu J, Wu Y, Liao S, Ding X. | 02/6/2021 |
| von Willebrand Factor and Platelet Glycoprotein Ib: A Thromboinflammatory Axis in Stroke. | von Willebrand Factor and Platelet Glycoprotein Ib: A Thromboinflammatory Axis in Stroke.
Denorme F, Vanhoorelbeke K, De Meyer SF., Free PMC Article | 11/21/2020 |
| Platelet-type von Willebrand disease: Local disorder of the platelet GPIbalpha beta-switch drives high-affinity binding to von Willebrand factor. | Platelet-type von Willebrand disease: Local disorder of the platelet GPIbα β-switch drives high-affinity binding to von Willebrand factor.
Tischer A, Machha VR, Moon-Tasson L, Auton M. | 09/12/2020 |
| T cell-derived soluble glycoprotein GPIbalpha mediates PGE2 production in human monocytes activated with the vaccine adjuvant MDP. | T cell-derived soluble glycoprotein GPIbα mediates PGE(2) production in human monocytes activated with the vaccine adjuvant MDP.
Liu F, Endo Y, Romantseva T, Wu WW, Akue A, Shen RF, Golding H, Zaitseva M. | 08/15/2020 |
| novel missense mutation in a leucine-rich repeat of GPIbalpha in a Bernard-Soulier variant reduces shear-dependent adherence on von Willebrand factor. | A novel missense mutation in a leucine-rich repeat of GPIbα in a Bernard-Soulier variant reduces shear-dependent adherence on von Willebrand factor.
Proulle V, Strassel C, Perrault C, Baas MJ, Moog S, Mangin P, Nurden P, Nurden A, Adam F, Bryckaert M, Kauskot A, Li R, Lanza F. | 06/6/2020 |
| Mouse platelets lacking the extracellular domain of GPIbalpha and human platelets treated with GPIbalpha-blocking antibodies display a reduced aggregation response to synthetic glycopolymers. We found that synthetic sulfated glycopolymers bind directly to GPIbalpha, substantiating that GPIbalpha facilitates the interaction of synthetic glycopolymers with CLEC-2 or PEAR1. | Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα.
Kardeby C, Fälker K, Haining EJ, Criel M, Lindkvist M, Barroso R, Påhlsson P, Ljungberg LU, Tengdelius M, Rainger GE, Watson S, Eble JA, Hoylaerts MF, Emsley J, Konradsson P, Watson SP, Sun Y, Grenegård M., Free PMC Article | 03/21/2020 |
| Platelet protein disulfide isomerase-facilitated cleavage of the allosteric disulfide bonds tightly regulates GPIbalpha function, promoting platelet-neutrophil interactions, vascular occlusion, and tissue damage under thromboinflammatory conditions. | Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions.
Li J, Kim K, Jeong SY, Chiu J, Xiong B, Petukhov PA, Dai X, Li X, Andrews RK, Du X, Hogg PJ, Cho J., Free PMC Article | 12/21/2019 |
| A new heterozygous mutation in GP1BA gene responsible for macrothrombocytopenia. | A new heterozygous mutation in GP1BA gene responsible for macrothrombocytopenia.
Ghalloussi D, Saut N, Bernot D, Pillois X, Rameau P, Sébahoun G, Alessi MC, Raslova H, Baccini V. | 07/20/2019 |
| In GPIbalpha-deficient human Bernard-Soulier syndrome patients, a decrease occurred in circulating TPO. | GPIbα is required for platelet-mediated hepatic thrombopoietin generation.
Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus AH, Ruggeri ZM, Freedman J, Ni H. | 07/20/2019 |
| An autosomal dominant mode of inheritance, a family history of mild bleeding episodes, aggregation pattern in affected individuals together with evidence of mutation occurring in part of the GP1BA gene encoding the leucine-rich repeat region suggest a novel variant causing monoallelic Bernard-Soulier syndrome. | A novel germline mutation in GP1BA gene N-terminal domain in monoallelic Bernard-Soulier syndrome.
Trizuljak J, Kozubík KS, Radová L, Pešová M, Pál K, Réblová K, Stehlíková O, Smejkal P, Zavřelová J, Pacejka M, Mayer J, Pospíšilová Š, Doubek M. | 12/22/2018 |
| Combined deficiency of factors V and VIII by chance coinheritance of parahaemophilia and haemophilia A, but not by mutations of either LMAN1 or MCFD2 | Bernard-Soulier syndrome in Pakistan: Biochemical and molecular analyses leading to identification of a novel mutation in GP1BA.
Böckelmann D, Naz A, Siddiqi MYJ, Lerner E, Sandrock-Lang K, Shamsi TS, Zieger B. | 09/15/2018 |
| A review of mutations associated with Bernard-Soulier Syndrome and platelet type von Willebrand disease (review). | Gene of the issue: GP1BA gene mutations associated with bleeding.
Othman M, Emsley J. | 07/14/2018 |
| ERK5 associates with CKII to play essential roles in GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway. | Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway.
Cheng Z, Gao W, Fan X, Chen X, Mei H, Liu J, Luo X, Hu Y. | 05/5/2018 |
| There was no evidence to suggest that polymorphisms of GP VI T13254C and GP Ibalpha VNTR were associated with CAD. | Association of Platelet Membrane Glycoprotein HPA-2a/b, GP VI T13254C, and GP Ibα VNTR Polymorphisms with Risk of Coronary Artery Disease: A Meta-Analysis.
Ni W, He J, Wang H, Liu T., Free PMC Article | 03/17/2018 |
| analysis of an artificial botrocetin that can inhibit the VWF-GPIb interaction | Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.
Matsui T, Hori A, Hamako J, Matsushita F, Ozeki Y, Sakurai Y, Hayakawa M, Matsumoto M, Fujimura Y. | 02/3/2018 |
| Loss of the platelet surface receptors GPIbalpha and GPVI in heart failure, CF-VAD and ECMO patients may contribute to ablated platelet adhesion/activation, and limit thrombus formation under high/pathologic shear conditions | Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI.
Lukito P, Wong A, Jing J, Arthur JF, Marasco SF, Murphy DA, Bergin PJ, Shaw JA, Collecutt M, Andrews RK, Gardiner EE, Davis AK. | 01/6/2018 |