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    Kiss1 KiSS-1 metastasis-suppressor [ Mus musculus (house mouse) ]

    Gene ID: 280287, updated on 9-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The role of placental kisspeptin in trophoblast invasion and migration: an assessment in Kiss1r knockout mice, BeWo cell lines and human term placenta.

    The role of placental kisspeptin in trophoblast invasion and migration: an assessment in Kiss1r knockout mice, BeWo cell lines and human term placenta.
    Panting EN, Weight JH, Sartori JA, Coall DA, Smith JT.

    08/1/2024
    Adipose Kiss1 controls aerobic exercise-related adaptive responses in adipose tissue energy homeostasis.

    Adipose Kiss1 controls aerobic exercise-related adaptive responses in adipose tissue energy homeostasis.
    Liang C, Li X, Song G, Schmidt SF, Sun L, Chen J, Pan X, Zhao H, Yan Y.

    06/28/2024
    STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway.

    STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway.
    Zhang X, Wang Y, Lv J.

    04/11/2024
    Deletion of Androgen Receptors From Kisspeptin Neurons Prevents PCOS Features in a Letrozole Mouse Model.

    Deletion of Androgen Receptors From Kisspeptin Neurons Prevents PCOS Features in a Letrozole Mouse Model.
    Decourt C, Watanabe Y, Evans MC, Inglis MA, Fisher LC, Jasoni CL, Campbell RE, Anderson GM., Free PMC Article

    06/18/2023
    Kisspeptin regulates airway hyperresponsiveness and remodeling in a mouse model of asthma.

    Kisspeptin regulates airway hyperresponsiveness and remodeling in a mouse model of asthma.
    Borkar NA, Ambhore NS, Balraj P, Ramakrishnan YS, Sathish V., Free PMC Article

    06/15/2023
    Kisspeptin induces Kiss-1 and GnRH gene expression in mHypoA-55 hypothalamic cell models: Involvement of the ERK and PKA signaling pathways.

    Kisspeptin induces Kiss-1 and GnRH gene expression in mHypoA-55 hypothalamic cell models: Involvement of the ERK and PKA signaling pathways.
    Tumurbaatar T, Kanasaki H, Yacca SS, Cairang Z, Tumurgan Z, Oride A, Okada H, Kyo S.

    05/13/2023
    SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.

    SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
    Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y., Free PMC Article

    04/12/2023
    Deletion of GABAB receptors from Kiss1 cells affects glucose homeostasis without altering reproduction in male mice.

    Deletion of GABAB receptors from Kiss1 cells affects glucose homeostasis without altering reproduction in male mice.
    Di Giorgio NP, Bizzozzero-Hiriart M, Surkin PN, Repetto E, Bonaventura MM, Tabares FN, Bourguignon NS, Converti A, Gomez JMR, Bettler B, Lux-Lantos V.

    03/24/2023
    Optogenetic stimulation of Kiss1[ARC] terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice.

    Optogenetic stimulation of Kiss1(ARC) terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice.
    Shen X, Liu Y, Li XF, Long H, Wang L, Lyu Q, Kuang Y, O'Byrne KT., Free PMC Article

    12/3/2022
    Socs3 ablation in kisspeptin cells partially prevents lipopolysaccharide-induced body weight loss.

    Socs3 ablation in kisspeptin cells partially prevents lipopolysaccharide-induced body weight loss.
    Bohlen TM, de Paula DG, Teixeira PDS, da Silva Mansano N, Andrade Alves G, Donato J Jr, Frazao R.

    10/1/2022
    Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice.

    Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice.
    Jamieson BB, Moore AM, Lohr DB, Thomas SX, Coolen LM, Lehman MN, Campbell RE, Piet R., Free PMC Article

    09/17/2022
    Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.

    Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
    Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M., Free PMC Article

    08/20/2022
    Developmental sex differences in the peri-pubertal pattern of hypothalamic reproductive gene expression, including Kiss1 and Tac2, may contribute to sex differences in puberty onset.

    Developmental sex differences in the peri-pubertal pattern of hypothalamic reproductive gene expression, including Kiss1 and Tac2, may contribute to sex differences in puberty onset.
    Semaan SJ, Kauffman AS., Free PMC Article

    06/18/2022
    Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1.

    Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1.
    Lavalle SN, Chou T, Hernandez J, Naing NCP, Tonsfeldt KJ, Hoffmann HM, Mellon PL., Free PMC Article

    01/15/2022
    Kisspeptin-54 injection induces a physiological luteinizing hormone surge and ovulation in mice.

    Kisspeptin-54 injection induces a physiological luteinizing hormone surge and ovulation in mice.
    Owen CM, Zhou X, Bernard DJ, Jaffe LA., Free PMC Article

    01/8/2022
    Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism.

    Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism.
    Nandankar N, Negrón AL, Wolfe A, Levine JE, Radovick S., Free PMC Article

    09/25/2021
    Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion.

    Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion.
    Berthon A, Settas N, Delaney A, Giannakou A, Demidowich A, Faucz FR, Seminara SB, Chen ME, Stratakis CA., Free PMC Article

    09/4/2021
    MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway.

    MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway.
    Li X, Xiao J, Li K, Zhou Y.

    07/3/2021
    Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice.

    Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice.
    Minabe S, Nakamura S, Fukushima E, Sato M, Ikegami K, Goto T, Sanbo M, Hirabayashi M, Tomikawa J, Imamura T, Inoue N, Uenoyama Y, Tsukamura H, Maeda KI, Matsuda F., Free PMC Article

    07/3/2021
    Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice.

    Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice.
    Ikegami K, Goto T, Nakamura S, Watanabe Y, Sugimoto A, Majarune S, Horihata K, Nagae M, Tomikawa J, Imamura T, Sanbo M, Hirabayashi M, Inoue N, Maeda KI, Tsukamura H, Uenoyama Y., Free PMC Article

    07/3/2021
    KISS1/KISS1R mediates Sertoli cell apoptosis via the PI3K/AKT signalling pathway in a highglucose environment.

    KISS1/KISS1R mediates Sertoli cell apoptosis via the PI3K/AKT signalling pathway in a high‑glucose environment.
    Gan DM, Zhang PP, Zhang JP, Ding SX, Fang J, Liu Y.

    05/15/2021
    Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases luteinising hormone pulse frequency in female mice.

    Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases luteinising hormone pulse frequency in female mice.
    Lass G, Li XF, de Burgh RA, He W, Kang Y, Hwa-Yeo S, Sinnett-Smith LC, Manchishi SM, Colledge WH, Lightman SL, O'Byrne KT., Free PMC Article

    05/15/2021
    ERalpha Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty.

    ERα Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty.
    Garcia-Galiano D, Cara AL, Tata Z, Allen SJ, Myers MG Jr, Schipani E, Elias CF., Free PMC Article

    02/13/2021
    MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.

    MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.
    Abreu AP, Toro CA, Song YB, Navarro VM, Bosch MA, Eren A, Liang JN, Carroll RS, Latronico AC, Rønnekleiv OK, Aylwin CF, Lomniczi A, Ojeda S, Kaiser UB., Free PMC Article

    02/6/2021
    Testosterone Supplementation Rescues Spermatogenesis and In Vitro Fertilizing Ability of Sperm in Kiss1 Knockout Mice.

    Testosterone Supplementation Rescues Spermatogenesis and In Vitro Fertilizing Ability of Sperm in Kiss1 Knockout Mice.
    Goto T, Hirabayashi M, Watanabe Y, Sanbo M, Tomita K, Inoue N, Tsukamura H, Uenoyama Y.

    01/9/2021
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